Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Katelyn McCabe Willis"'
Autor:
Joe Ryan Delaney, Chandni B. Patel, Katelyn McCabe Willis, Mina Haghighiabyaneh, Joshua Axelrod, Isabelle Tancioni, Dan Lu, Jaidev Bapat, Shanique Young, Octavia Cadassou, Alena Bartakova, Parthiv Sheth, Carley Haft, Sandra Hui, Cheryl Saenz, David D. Schlaepfer, Olivier Harismendy, Dwayne G. Stupack
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Cancers accumulate multiple single copy number alterations, but their impact is unclear. Here, the authors computationally demonstrate a disruption of genes associated with autophagy in ovarian cancer, show impact on autophagic flux, and note the eff
Externí odkaz:
https://doaj.org/article/4693ab4669b34978ad4a226632a7b4a7
Autor:
Chandni Patel, Dan Lu, Joshua Axelrod, Katelyn McCabe Willis, Dwayne G. Stupack, Isabelle Tancioni, Sandra Hui, David D. Schlaepfer, Shanique Young, Octavia Cadassou, Parthiv Sheth, Carley Haft, Jaidev Bapat, Cheryl C. Saenz, Mina Haghighiabyaneh, Olivier Harismendy, Alena Bartakova, Joe R. Delaney
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Nature communications, vol 8, iss 1
Delaney, JR; Patel, CB; Willis, KM; Haghighiabyaneh, M; Axelrod, J; Tancioni, I; et al.(2017). Haploinsufficiency networks identify targetable patterns of allelic deficiency in low mutation ovarian cancer. NATURE COMMUNICATIONS, 8. doi: 10.1038/ncomms14423. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/5vp9070r
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Nature communications, vol 8, iss 1
Delaney, JR; Patel, CB; Willis, KM; Haghighiabyaneh, M; Axelrod, J; Tancioni, I; et al.(2017). Haploinsufficiency networks identify targetable patterns of allelic deficiency in low mutation ovarian cancer. NATURE COMMUNICATIONS, 8. doi: 10.1038/ncomms14423. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/5vp9070r
Identification of specific oncogenic gene changes has enabled the modern generation of targeted cancer therapeutics. In high-grade serous ovarian cancer (OV), the bulk of genetic changes is not somatic point mutations, but rather somatic copy-number
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f6f59052e1381187b497e2e9e6fa0f1
https://pubmed.ncbi.nlm.nih.gov/28198375
https://pubmed.ncbi.nlm.nih.gov/28198375