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pro vyhledávání: '"Katelyn J. Nagy"'
Publikováno v:
Biomaterials. 37:62-72
Hydrogels formed from self-assembling peptides are finding use in tissue engineering and drug delivery applications. Given the notorious difficulties associated with producing self-assembling peptides by recombinant expression, most are typically pre
Publikováno v:
Biomaterials. 33(30)
Iterative peptide design was used to generate two peptide-based hydrogels to study the effect of network electrostatics on primary chondrocyte behavior. MAX8 and HLT2 peptides have formal charge states of +7 and +5 per monomer, respectively. These pe
Publikováno v:
Journal of the American Chemical Society. 133(38)
Chirality can be used as a design tool to control the mechanical rigidity of hydrogels formed from self-assembling peptides. Hydrogels prepared from enantiomeric mixtures of self-assembling β-hairpins show non-additive, synergistic, enhancement in m
Autor:
Katelyn J. Nagy, Daniel J. Smith, Joel P. Schneider, Dedi Tong, Gerald Brandacher, Johanna Grahammer, Gabriel A. Brat, Yong Huang
Publikováno v:
Journal of the American College of Surgeons. 219:e90-e91
Publikováno v:
Chemistry & Biology. (4):604-613
The dynamic, posttranslational modification of proteins with a SUMO tag has been recognized as an important cellular regulatory mechanism relevant to a number of cancers as well as normal embryonic development. As part of a program aimed towards the