Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Katelyn J Smith"'
Publikováno v:
Journal of pharmaceutical sciences. 111(3)
The presence of subvisible or visible particles in mAb formulations can create significant challenges to the pharmaceutical development as it can lead to reduced shelf life, batch rejection, and recalls. Among all type of particles, proteinaceous par
Autor:
Michael A. Bertucci, Katelyn J. Smith
Publikováno v:
Peptide Science. 112
Autor:
Yong Liu, Yuejie Zhao, Katelyn J. Smith, Michelle Chen, Andreas Abend, Xiujuan Jia, Angela M. Wagner, Justin Pennington, Dan Some
Publikováno v:
Journal of Chromatography B. 1186:123015
The potential of lipid nanoparticles (LNPs) as nucleic acid delivery vehicles has been demonstrated in recent years, culminating in the emergency use approval of LNP-based mRNA SARS-CoV-2 vaccines in late 2020. The determination of RNA content relati
Autor:
Venkata S. Mandala, Mei Hong, Yongchao Su, Katelyn J. Smith, Yu Tian, Darrin J. Pochan, Wei Xu, Martin D. Gelenter, Shu-Yu Liao, Matthew S. Lamm, Thomas J. Tucker, Aurelio J. Dregni
Publikováno v:
PMC
Nature structural & molecular biology
Nature structural & molecular biology
Glucagon and insulin maintain blood glucose homeostasis and are used to treat hypoglycemia and hyperglycemia, respectively, in patients with diabetes. Whereas insulin is stable for weeks in its solution formulation, glucagon fibrillizes rapidly at th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58b852b09be0223b81ec95416d0fda9a
https://hdl.handle.net/1721.1/125383
https://hdl.handle.net/1721.1/125383
Autor:
Leo A. Joyce, Yogita Krishnamachari, Alexandra Andrews, Sandhya Kashi, Katelyn J Smith, Jameson R. Bothe
Publikováno v:
Molecular pharmaceutics. 16(5)
Peptides and proteins commonly have complex structural landscapes allowing for transformation into a wide array of species including oligomers, aggregates, and fibrils. The formation of undesirable forms including aggregates and fibrils poses serious
Publikováno v:
Volume 1B: Codes and Standards.
The 2014 Edition of ASME B31.3, Process Piping [1], introduced significant changes to the post weld heat treatment (PWHT) requirements for P-No. 1 carbon steel materials. In particular, PWHT is no longer a mandatory requirement for any wall thickness
Publikováno v:
Muscle & Nerve. 43:716-725
Introduction: Bergstrom needle muscle biopsies have been used by exercise physiologists for over 35 years but have been less accepted by neuromuscular clinicians due to size concerns. Methods: We retrospectively reviewed over 13,500 muscle Bergstrom
Autor:
David J. Dewees, Katelyn J. Smith
Publikováno v:
Volume 1: Codes and Standards.
Guidance for weld residual stress (WRS) in flaw assessments of in-service equipment is given in Annex E of the Fitness-for-Service (FFS) standard, API 579-1/ASME FFS-1. Recent progress in the simulation of weld residual stress, and in its verificatio