Alteration of microbiota antibody‐mediated immune selection contributes to dysbiosis in inflammatory bowel diseases

Autor: Eva Michaud, Louis Waeckel, Rémi Gayet, Roman Goguyer‐Deschaumes, Blandine Chanut, Fabienne Jospin, Katell Bathany, Magali Monnoye, Coraline Genet, Amelie Prier, Caroline Tokarski, Philippe Gérard, Xavier Roblin, Nicolas Rochereau, Stéphane Paul

Publikováno v: EMBO Molecular Medicine, Vol 14, Iss 8, Pp 1-21 (2022)

Abstract Human secretory immunoglobulins (SIg) A1 and SIgA2 guide mucosal responses toward tolerance or inflammation, notably through reverse‐transcytosis, the apical‐to‐basal transport of IgA2 immune complexes via M cells of gut Peyer's patche

Externí odkaz: https://doaj.org/article/412ce5dad93d49a68a3f2f1a2bf9f560

Oxidative Transformation of Dihydroflavonols and Flavan-3-ols by Anthocyanidin Synthase from Vitis vinifera

Autor: Jia-Rong Zhang, Claudine Trossat-Magnin, Katell Bathany, Luc Negroni, Serge Delrot, Jean Chaudière

Publikováno v: Molecules, Vol 27, Iss 3, p 1047 (2022)

Twelve polyphenols from three distinct families (dihydroflavonols, flavan-3-ols, and flavanones) were studied as potential substrates of anthocyanidin synthase from Vitis vinifera (VvANS). Only flavan-3-ols of (2R,3S) configuration having either a ca

Externí odkaz: https://doaj.org/article/54488813a913466988b219e6ebccde71

Nucleic acids complexation with cationic elastin-like polypeptides: Stoichiometry and stability of nano-assemblies

Autor: Julien Rosselgong, Bertrand Garbay, Y. Xia, Elisabeth Garanger, F. Carvajal Ramos, J.L.E. Nando-Rodríguez, Katell Bathany, Sébastien Lecommandoux, Emmanuel Ibarboure, Gilles Joucla, L.M. Bravo-Anaya

Publikováno v: Journal of Colloid and Interface Science
Journal of Colloid and Interface Science, Elsevier, 2019, 557, pp.777-792. ⟨10.1016/j.jcis.2019.09.054⟩

International audience; Positively charged elastin-like polypeptides (ELPs) were synthesized for the compaction of genetic material. A recombinant ELP (VPGXG)40 with X = V,M (3:1) was post-modified in two steps to introduce chemoselectively either pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96a6591548620e89c0b965e78a3727a4
https://doi.org/10.1016/j.jcis.2019.09.054

Selective Tuning of Elastin-like Polypeptide Properties via Methionine Oxidation

Autor: Elisabeth Garanger, Wilfrid Dieryck, Timothy J. Deming, Laure Bataille, Rosine Petitdemange, Katell Bathany, Bertrand Garbay, Sébastien Lecommandoux

Publikováno v: Biomacromolecules
Biomacromolecules, American Chemical Society, 2017, 18 (2), pp.544-550. ⟨10.1021/acs.biomac.6b01696⟩
pubs.acs.org/doi/abs/10.1021/acs.biomac.6b01696
Biomacromolecules, vol 18, iss 2

International audience; We have designed and prepared a recombinant elastin-like polypeptide (ELP) containing precisely positioned methionine residues, and performed the selective and complete oxidation of its methionine thioether groups to both sulf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::971cf66940c31d6e87b5de4f208d35dd
https://doi.org/10.1021/acs.biomac.6b01696

The transmembrane domain of the SNARE protein VAMP2 is highly sensitive to its lipid environment

Autor: Zahia Fezoua-Boubegtiten, Bernard Desbat, Reiko Oda, Jochen Lang, Katell Bathany, Alexandra Milochau, Sabine Castano, Benoit Hastoy, Pier Scotti

Publikováno v: Biochimica et Biophysica Acta:Biomembranes
Biochimica et Biophysica Acta:Biomembranes, Elsevier, 2019, 1861 (3), pp.670-676. ⟨10.1016/j.bbamem.2018.12.011⟩
Biochimica et Biophysica Acta:Biomembranes, Elsevier, 2019, 1861 (3), pp.670-676

International audience; Neurotransmitter and hormone exocytosis depends on SNARE protein transmembrane domains and membrane lipids but their interplay is poorly understood. We investigated the interaction of the structure of VAMP2, a vesicular transm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc1c494488f0cfab12a5a2b0bc89bdf1
https://doi.org/10.1016/j.bbamem.2018.12.011