Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Kate de Mattos-Shipley"'
Autor:
Risa Nofiani, Kate de Mattos-Shipley, Karen E. Lebe, Li-Chen Han, Zafar Iqbal, Andrew M. Bailey, Christine L. Willis, Thomas J. Simpson, Russell J. Cox
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Strobilurins are fungal metabolites that inspired the creation of β-methoxyacrylate agricultural fungicides. Here, Nofiani et al. identify the strobilurin biosynthesis gene cluster, encoding a polyketide synthase as well as an FAD-dependent oxygenas
Externí odkaz:
https://doaj.org/article/71b50d3e4230482bbedb9a03d418d152
Autor:
David S. Pitcher, Kate de Mattos-Shipley, Konstantinos Tzortzis, Holger W. Auner, Anastasios Karadimitris, Maurits F. Kleijnen
Publikováno v:
EBioMedicine, Vol 2, Iss 7, Pp 642-648 (2015)
The proteasome inhibitor Bortezomib is used to treat multiple myeloma (MM). Bortezomib inhibits protein degradation by inactivating proteasomes' active-sites. MM cells are exquisitely sensitive to Bortezomib – exhibiting a low-nanomolar IC50 – su
Externí odkaz:
https://doaj.org/article/dac0543ad72f41d1be390db0bd98e837
Autor:
Kate de Mattos-Shipley
Publikováno v:
Nature chemical biology. 18(12)
Autor:
Kate De Mattos-Shipley, Thomas Simpson
Publikováno v:
Natural product reports.
A large and diverse family of fungal compounds are those related to the anthraquinone emodin. By viewing this family as a whole and combining our genetic and chemical understanding, we gain detailed insights into their biosynthetic origins.
Autor:
Kate de Mattos-Shipley
Publikováno v:
Nature chemical biology. 18(3)
Autor:
Kate de Mattos-Shipley
Publikováno v:
Nature Chemical Biology. 19:251-251
Autor:
Kate de Mattos-Shipley
Publikováno v:
Nature chemical biology. 18(1)
Autor:
Kate, de Mattos-Shipley
Publikováno v:
Nature Chemical Biology. 18:679-679
Autor:
Kate, de Mattos-Shipley
Publikováno v:
Nature Chemical Biology. 18:354-354
Autor:
David S. Pitcher, Amin Rahemtulla, Irene Roberts, Maurits F. Kleijnen, Ziming Wang, Kate de Mattos-Shipley, Katerina Goudevenou, Ambrosius P. Snijders, Georg Bohn, Konstantinos N. Tzortzis, Anastasios Karadimitris, Helen R. Flynn
Publikováno v:
Europe PubMed Central
We report that subunits of human nuclear proteasomes carry a previously unrecognised, constitutive posttranslational modification. Subunits with this modification are not visualised by SDS-PAGE, which is used in almost all denaturing protein gel elec