Zobrazeno 1 - 9
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pro vyhledávání: '"Kate T. Davis"'
Relative differences in expression of circadian clock genes between cell lines remains the same at different time points after synchronisation. A. Western blot analysis showing similarly downregulated CLOCK and CRY1 protein levels in HeLa cells compa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57cfa8402448d1063beabf5fcd0600ae
https://doi.org/10.1158/1541-7786.22514451.v1
https://doi.org/10.1158/1541-7786.22514451.v1
Microarray analysis showing significant downregulation of circadian clock gene, PER2, in cervical cancer tissue specimens (n = 16) compared to normal cervical epithelium (n = 8); *p < 0.0005.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cad027ca3d1b054b53ec576851a9e78
https://doi.org/10.1158/1541-7786.22514463.v1
https://doi.org/10.1158/1541-7786.22514463.v1
Real-time RT-PCR analysis reveals expression of certain circadian clock genes to be unaltered in cancer/transformed cells compared to normal. A. Relative expression of REV-ERBβ and RORβ in transformed SVWI38 compared to normal WI38 fibroblast cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56a3191842e252cc615ec84fe1a30154
https://doi.org/10.1158/1541-7786.22514457.v1
https://doi.org/10.1158/1541-7786.22514457.v1
Correlations between gene expression fold changes (R values are shown)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3caaaa0a010a39d56f4e8661fa778f6d
https://doi.org/10.1158/1541-7786.22514433.v1
https://doi.org/10.1158/1541-7786.22514433.v1
CpG island prediction software, MethPrimer (www.urogene.org), identifies CpG islands in the 5' regulatory sequences of circadian clock genes, CLOCK, RORα, CRY1 and PER2. The regions from -2000 to +2000 were analysed, relative to the transcription st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cc26e02756e087caba7e677c35c899c
https://doi.org/10.1158/1541-7786.22514448
https://doi.org/10.1158/1541-7786.22514448
Supplementary figure legends
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https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e25efc297ea41fa890848148866c5a8
https://doi.org/10.1158/1541-7786.22514436.v1
https://doi.org/10.1158/1541-7786.22514436.v1
WI38 and SVWI38 cell sensitivities to REV-ERBα and RORα agonists, SR9011 and SR1078. A. MTT analysis reveals transformed SVWI38 cells to be more sensitive to REV-ERBα activation, compared to normal WI38 cells. B. WI38 and SVWI38 cells are both sen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b9b90ca295444dc1b2c292ca0b1bf1e
https://doi.org/10.1158/1541-7786.22514442.v1
https://doi.org/10.1158/1541-7786.22514442.v1
Real-time bioluminescence monitoring showing PER2-dLUC activity in unsynchronised HeLa (A) and WHCO5 (B) cells over time. Bioluminescence readings were obtained using an IVIS Lumina II (PerkinElmer).
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https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d509bede3b413eead2c218e39f5a6c2
https://doi.org/10.1158/1541-7786.22514439
https://doi.org/10.1158/1541-7786.22514439
Relative circadian clock gene expression in normal and cancer tissue, as calculated based on data generated by the TCGA Research Network (https://www.cancer.gov/tcga) and The Genotype Tissue Expression (GTEx) project (https://www.gtexportal.org/home/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a4ea6009e417e0ed5b24374da5487ab
https://doi.org/10.1158/1541-7786.22514460
https://doi.org/10.1158/1541-7786.22514460