Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Kate Medetgul-Ernar"'
Autor:
Nikolaos Vakirlis, Omer Acar, Brian Hsu, Nelson Castilho Coelho, S. Branden Van Oss, Aaron Wacholder, Kate Medetgul-Ernar, Ray W. Bowman, Cameron P. Hines, John Iannotta, Saurin Bipin Parikh, Aoife McLysaght, Carlos J. Camacho, Allyson F. O’Donnell, Trey Ideker, Anne-Ruxandra Carvunis
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
There is increasing evidence that protein-coding genes can emerge de novo from noncoding genomic regions. Vakirlis et al. propose that sequences encoding transmembrane polypeptides can emerge de novo in thymine-rich genomic regions and provide organi
Externí odkaz:
https://doaj.org/article/faf179aee3974a3a939a01b1132508f8
Autor:
Mizuo Ando, Yuki Saito, Guorong Xu, Nam Q. Bui, Kate Medetgul-Ernar, Minya Pu, Kathleen Fisch, Shuling Ren, Akihiro Sakai, Takahito Fukusumi, Chao Liu, Sunny Haft, John Pang, Adam Mark, Daria A. Gaykalova, Theresa Guo, Alexander V. Favorov, Srinivasan Yegnasubramanian, Elana J. Fertig, Patrick Ha, Pablo Tamayo, Tatsuya Yamasoba, Trey Ideker, Karen Messer, Joseph A. Califano
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
In tumours aberrant epigenetic modifications can alter the transcriptional state. Here, the authors identify a common tumour-specific shift to transcriptional repression associated with DNA methylation and chromatin dysregulation at the transcription
Externí odkaz:
https://doaj.org/article/92171efeb0c747ec87436ef09a8ab860
Autor:
Nikolaos Vakirlis, Omer Acar, Brian Hsu, Nelson Castilho Coelho, S. Branden Van Oss, Aaron Wacholder, Kate Medetgul-Ernar, Ray W. Bowman, Cameron P. Hines, John Iannotta, Saurin Bipin Parikh, Aoife McLysaght, Carlos J. Camacho, Allyson F. O’Donnell, Trey Ideker, Anne-Ruxandra Carvunis
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
A Correction to this paper has been published: https://doi.org/10.1038/s41467-020-20609-y.
Externí odkaz:
https://doaj.org/article/5b04002d1b06458bb822acc60c420688
Autor:
Mizuo Ando, Yuki Saito, Guorong Xu, Nam Q. Bui, Kate Medetgul-Ernar, Minya Pu, Kathleen Fisch, Shuling Ren, Akihiro Sakai, Takahito Fukusumi, Chao Liu, Sunny Haft, John Pang, Adam Mark, Daria A. Gaykalova, Theresa Guo, Alexander V. Favorov, Srinivasan Yegnasubramanian, Elana J. Fertig, Patrick Ha, Pablo Tamayo, Tatsuya Yamasoba, Trey Ideker, Karen Messer, Joseph A. Califano
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
The original version of this Article contained an error in the author affiliations. Trey Ideker was incorrectly associated with ‘Department of Medicine (Oncology), Stanford University School of Medicine, 875 Blake Wilbur Dr, Palo Alto, CA 94304, US
Externí odkaz:
https://doaj.org/article/bb424e1b699744da92ba17c599482181
Autor:
Alexander V. Favorov, Joseph A. Califano, Nam Bui, Pablo Tamayo, Elana J. Fertig, John Pang, Kathleen M. Fisch, Trey Ideker, Yuki Saito, Daria A. Gaykalova, Chao Liu, Mizuo Ando, Patrick K. Ha, Adam Mark, Karen Messer, Tatsuya Yamasoba, Guorong Xu, Srinivasan Yegnasubramanian, Shuling Ren, Minya Pu, Akihiro Sakai, Takahito Fukusumi, Sunny Haft, Kate Medetgul-Ernar, Theresa Guo
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Nature communications, vol 10, iss 1
Nature Communications
Nature communications, vol 10, iss 1
Nature Communications
Although promoter-associated CpG islands have been established as targets of DNA methylation changes in cancer, previous studies suggest that epigenetic dysregulation outside the promoter region may be more closely associated with transcriptional cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81336fc4ce9ad84747875161659b7948
https://doaj.org/article/92171efeb0c747ec87436ef09a8ab860
https://doaj.org/article/92171efeb0c747ec87436ef09a8ab860
Autor:
Kathleen M. Fisch, Srinivasan Yegnasubramanian, Minya Pu, John Pang, Kate Medetgul-Ernar, Trey Ideker, Tatsuya Yamasoba, Alexander V. Favorov, Guorong Xu, Nam Bui, Sunny Haft, Yuki Saito, Akihiro Sakai, Elana J. Fertig, Adam Mark, Takahito Fukusumi, Pablo Tamayo, Chao Liu, Shuling Ren, Theresa Guo, Karen Messer, Daria A. Gaykalova, Joseph A. Califano, Mizuo Ando, Patrick K. Ha
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
Nature communications, vol 10, iss 1
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
Nature communications, vol 10, iss 1
Although promoter-associated CpG islands have been established as targets of DNA methylation changes in cancer, previous studies suggest that epigenetic dysregulation outside the promoter region may be more closely associated with transcriptional cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccffd13ae77805770e90515de1f63fbe
http://europepmc.org/articles/PMC6541594
http://europepmc.org/articles/PMC6541594
Autor:
Nikolaos Vakirlis, Aaron C. Wacholder, Aoife McLysaght, Carlos J. Camacho, Trey Ideker, John Iannotta, Omer Acar, Allyson F. O'Donnell, Nelson C. Coelho, Anne-Ruxandra Carvunis, Brian Hsu, S. Branden Van Oss, Kate Medetgul-Ernar
SummaryRecent evidence demonstrates that novel protein-coding genes can arisede novofrom intergenic loci. This evolutionary innovation is thought to be facilitated by the pervasive translation of intergenic transcripts, which exposes a reservoir of v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5295357fa7e3f8ead0e42877e42a00ba
Autor:
Trey Ideker, Brian Hsu, Ray W. Bowman, Aoife McLysaght, Cameron P. Hines, John Iannotta, Nikolaos Vakirlis, Kate Medetgul-Ernar, Allyson F. O'Donnell, Carlos J. Camacho, Omer Acar, Nelson C. Coelho, Anne-Ruxandra Carvunis, Aaron C. Wacholder, S. Branden Van Oss, Saurin Bipin Parikh
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
A Correction to this paper has been published: https://doi.org/10.1038/s41467-020-20609-y.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91abac803f5609d1e006539e64dc355a
https://doaj.org/article/5b04002d1b06458bb822acc60c420688
https://doaj.org/article/5b04002d1b06458bb822acc60c420688
Autor:
Jonathan Liang, Andrew J. Aguirre, David A. Barbie, Jong Wook Kim, Huwate Yeerna, Karina Meneses-Cime, Pablo Tamayo, Emily Damato, Mahmoud Ghandi, Jason Park, Kate Medetgul-Ernar, Chen-Hsiang Yeang, Michelle Stewart, Barbara A. Weir, Aviad Tsherniak, Jill P. Mesirov, David Thomas, Gabriella Alexe, William C. Hahn, Eliezer M. Van Allen, Taylor B. Cavazos, Paul A. Clemons, Russell W. Jenkins, Jesse S. Boehm, John G. Doench, Ofir Cohen, Stephanie Ting, Shunsuke Kitajima, Levi A. Garraway, Arthur Liberzon, Omar O. Abudayyeh, David J. Konieczkowski, John H McDermott, Clarence K. Mah, Aravind Subramanian, Francisca Vazquez
Publikováno v:
Cell systems, vol 5, iss 2
The systematic sequencing of the cancer genome has led to the identification of numerous genetic alterations in cancer. However, a deeper understanding of the functional consequences of thesealterations is necessary to guide appropriatetherapeutic st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::310a1a1d0a98f04bf241ee93696299f1
https://doi.org/10.1016/j.cels.2017.08.002
https://doi.org/10.1016/j.cels.2017.08.002