Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kate Madigan"'
Autor:
Stéphane de Botton, Thomas Cluzeau, Carlos Vigil, Rachel J. Cook, Philippe Rousselot, David A. Rizzieri, Jane L. Liesveld, Pierre Fenaux, Thorsten Braun, Anne Banos, Joseph G. Jurcic, Mikkael A. Sekeres, Michael R. Savona, Gail J. Roboz, Dale Bixby, Kate Madigan, Angela Volkert, Kristin Stephens, Qing Kang-Fortner, Kristen Baker, Sofia Paul, Michael McKeown, John Carulli, Matthew Eaton, Graeme Hodgson, Christopher Fiore, Michael J. Kelly, David A. Roth, Eytan M. Stein
Publikováno v:
Blood Advances. 7:1858-1870
A superenhancer at the retinoic acid receptor alpha (RARA) gene is associated with RARA mRNA overexpression in ∼30% of non-acute promyelocytic leukemia acute myeloid leukemia (AML) and in ∼50% of myelodysplastic syndromes (MDS). RARA overexpressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf7414920f4b50d1024fa6139bfaa558
https://doi.org/10.1182/bloodadvances.2022008806
https://doi.org/10.1182/bloodadvances.2022008806
Autor:
Ghayas C. Issa, Ibrahim Aldoss, John F. DiPersio, Branko Cuglievan, Richard M. Stone, Martha L. Arellano, Michael J. Thirman, Manish R. Patel, David Dickens, Shalini Shenoy, Neerav Shukla, Galit Rosen, Rebecca G. Bagley, Michael L. Meyers, Kate Madigan, Peter Ordentlich, Yu Gu, Steven Smith, Gerard M. McGeehan, Eytan Stein
Publikováno v:
Blood. 140:150-152
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::885a2d3d98a82924ef3913b11c4926a4
https://doi.org/10.1182/blood-2022-164849
https://doi.org/10.1182/blood-2022-164849
Autor:
Ghayas C. Issa, Branko Cuglievan, Eytan Stein, Martha L. Arellano, Andrius Žucenka, Nandita Khera, Richard M. Stone, Michael J. Thirman, John F. DiPersio, Nicole Karras, Yu Gu, Rebecca G. Bagley, Galit Rosen, David Tamang, Kimberly Dishman, Sushama Scalera, Michael L. Meyers, Kate Madigan, Nicole McNeer, Ibrahim Aldoss
Publikováno v:
Blood. 140:914-916
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8de19932f8a29ddba13169e64695a07
https://doi.org/10.1182/blood-2022-164600
https://doi.org/10.1182/blood-2022-164600
Autor:
Liana Gercheva-Kyuchukova, Huy Van Nguyen, Tim Mant, Catherine Bagot, Baisong Mei, Qifeng Yu, Margaret V. Ragni, Craig Benson, Kate Madigan, Toshko Lissitchkov, K. John Pasi, Margarita Timofeeva, Pratima Chowdary, Pencho Georgiev, Vasily Mamonov
Publikováno v:
Journal of Thrombosis and Haemostasis
Background Fitusiran, an investigational small interfering RNA therapy, reduces antithrombin production to rebalance hemostasis in people with hemophilia A or B, with or without inhibitors. Objectives To evaluate the safety and efficacy of fitusiran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8c4dd37dee07aac554599d82ced9e17
https://pubmed.ncbi.nlm.nih.gov/33587824
https://pubmed.ncbi.nlm.nih.gov/33587824
Autor:
Kun Qian, Gili Kenet, Alfica Sehgal, Benny Sørensen, Kate Madigan, Tami Livnat, Huy Van Nguyen
Publikováno v:
Blood cells, moleculesdiseases. 82
Antithrombin (AT) reduction has been shown to improve thrombin generation (TG) in haemophilia with or without inhibitors. As treatment with bypassing agents (BPAs) may be required in patients with breakthrough bleeding while receiving AT-lowering the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e27460f89aa5b380a76056d1bdf37a80
https://pubmed.ncbi.nlm.nih.gov/32066048
https://pubmed.ncbi.nlm.nih.gov/32066048
Autor:
Li Zhou, Matthew L. Eaton, Kate Madigan, Qing Kang-Fortner, Graeme Hodgson, Michael Kelly, Angela Volkert, David A. Roth, Christopher Fiore
Publikováno v:
Blood. 136:15-16
Introduction: Super-enhancer (SE) mapping in non-APL AML patient (pt) blasts identified RARα as a novel therapeutic target in approximately 30% of pts, who have elevated RARA gene expression. It was observed that the enhancer profile of this novel p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ba3e711e5a344c68f53b39a6ec4ca04
https://doi.org/10.1182/blood-2020-137323
https://doi.org/10.1182/blood-2020-137323
Autor:
Pallavi Jain, Toshko Lissitchkov, Savita Rangarajan, Inga Hegemann, Meredith C. Foster, Craig Benson, Margaret V. Ragni, Syed Rashid Saeed Kazmi, Kate Madigan, K. John Pasi, Qifeng Yu, Michael Desmond Creagh, Huy Van Nguyen, Ketaki Kadam, Charles R. M. Hay, Pratima Chowdary, Pencho Georgiev, Steve Austin, Shariq Ali
Publikováno v:
Blood. 132:2477-2477
Introduction Hemophilia A and hemophilia B are rare bleeding disorders characterized by insufficient thrombin generation due to deficiencies in factors VIII or IX, respectively. Standard treatment for hemophilia is currently based on replacement of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66b23701311216d56fdc7f888e080790
https://doi.org/10.1182/blood-2018-99-112998
https://doi.org/10.1182/blood-2018-99-112998