Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Kate M Warde"'
Senescence-induced immune remodeling facilitates metastatic adrenal cancer in a sex-dimorphic manner
Autor:
Kate M. Warde, Lorenzo J. Smith, Lihua Liu, Chris J. Stubben, Brian K. Lohman, Parker W. Willett, Julia L. Ammer, Guadalupe Castaneda-Hernandez, Sikiru O. Imodoye, Chenge Zhang, Kara D. Jones, Kimber Converso-Baran, H. Atakan Ekiz, Marc Barry, Michael R. Clay, Katja Kiseljak-Vassiliades, Thomas J. Giordano, Gary D. Hammer, Kaitlin J. Basham
Publikováno v:
Nature Aging.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2aa39a9d406572a35132f281304625e
https://doi.org/10.1038/s43587-023-00420-2
https://doi.org/10.1038/s43587-023-00420-2
Autor:
Nathan Mullen, Padraig T Donlon, Jan Sebek, Katen Duffy, Grazia Cappiello, Sarah Feely, Kate M Warde, Brendan Harhen, David P Finn, Paula M O'Shea, Punit Prakash, Martin O’Halloran, Michael C Dennedy
Publikováno v:
Endocrinology. 164
Primary aldosteronism is the most common cause of secondary hypertension. The first-line treatment adrenalectomy resects adrenal nodules and adjacent normal tissue, limiting suitability to those who present with unilateral disease. Use of thermal abl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c8d93694a58d9046e11da1e23fd04eb
https://doi.org/10.1210/endocr/bqad046
https://doi.org/10.1210/endocr/bqad046
Autor:
Kate M Warde, Yi Jan Lim, Eduardo Ribes Martinez, Felix Beuschlein, Paula O’Shea, Constanze Hantel, Michael Conall Dennedy
Introduction Adrenocortical carcinoma (ACC) is a rare aggressive cancer with low overall survival. Adjuvant mitotane improves survival but is limited by poor response rates and resistance. Mitotane’s efficacy is attributed to the accumulation of to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24265ee50ff9644224ca8c11319f00d0
https://www.zora.uzh.ch/id/eprint/228187/
https://www.zora.uzh.ch/id/eprint/228187/
Autor:
Nathan Mullen, Padraig T Donlon, Katen Duffy, Sarah Feely, Kate M Warde, Punit Prakash, Michael Conall Dennedy, Martin O’Halloran
Publikováno v:
Journal of the Endocrine Society. 6:A122-A123
Introduction Primary Aldosteronism is the most common cause of secondary hypertension. First-line treatment; adrenalectomy resects adrenal nodules and adjacent normal tissue, limiting suitability to those who present with unilateral disease. Use of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac60de5cdcf9011af7bfc352d77b6318
https://doi.org/10.1210/jendso/bvac150.250
https://doi.org/10.1210/jendso/bvac150.250
Autor:
Nathan Mullen, Padraig Donlon, Katen Duffy, Sarah Feely, Kate M Warde, Anna Sorushanova, Punit Prakash, Martin O'Halloran, Michael Conall Dennedy
Publikováno v:
Endocrine Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::041e477279c52e0e532e6a3cd605f4b8
https://doi.org/10.1530/endoabs.81.p644
https://doi.org/10.1530/endoabs.81.p644
Senescence-Induced Immune Remodeling Facilitates Metastatic Adrenal Cancer in a Sex-Dimorphic Manner
Autor:
Kate M. Warde, Lihua Liu, Lorenzo J. Smith, Brian K. Lohman, Chris J. Stubben, H. Atakan Ekiz, Julia L. Ammer, Kimber Converso-Baran, Thomas J. Giordano, Gary D. Hammer, Kaitlin J. Basham
Aging is a carcinogen that markedly increases cancer risk, yet we have limited mechanistic understanding of cancer initiation in aged cells. Here, we demonstrate induction of the hallmark aging process cellular senescence, triggered by loss of Wnt in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5cfadeccc109b321b91df3229686702
https://doi.org/10.1101/2022.04.29.488426
https://doi.org/10.1101/2022.04.29.488426