Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Kate M Parsons"'
Autor:
Chue Vin Chin, Jisha Antony, Sarada Ketharnathan, Anastasia Labudina, Gregory Gimenez, Kate M Parsons, Jinshu He, Amee J George, Maria Michela Pallotta, Antonio Musio, Antony Braithwaite, Parry Guilford, Ross D Hannan, Julia A Horsfield
Publikováno v:
eLife, Vol 9 (2020)
Mutations in genes encoding subunits of the cohesin complex are common in several cancers, but may also expose druggable vulnerabilities. We generated isogenic MCF10A cell lines with deletion mutations of genes encoding cohesin subunits SMC3, RAD21,
Externí odkaz:
https://doaj.org/article/468478a941f34ce89b0313a4e6cc727f
Autor:
Anne Steins, Christina Carroll, Fui Jiun Choong, Amee J George, Jin-Shu He, Kate M Parsons, Shouya Feng, Si Ming Man, Cathelijne Kam, Lex M van Loon, Perlita Poh, Rita Ferreira, Graham J Mann, Russell L Gruen, Katherine M Hannan, Ross D Hannan, Klaus-Martin Schulte
Publikováno v:
Life Science Alliance. 6:e202201875
Povidone-iodine (PVP-I) inactivates a broad range of pathogens. Despite its widespread use over decades, the safety of PVP-I remains controversial. Its extended use in the current SARS-CoV-2 virus pandemic urges the need to clarify safety features of
Autor:
Katherine M. Hannan, Priscilla Soo, Mei S. Wong, Justine K. Lee, Nadine Hein, Perlita Poh, Kira D. Wysoke, Tobias D. Williams, Christian Montellese, Lorey K. Smith, Sheren J. Al-Obaidi, Lorena Núñez-Villacís, Megan Pavy, Jin-Shu He, Kate M. Parsons, Karagh E. Loring, Tess Morrison, Jeannine Diesch, Gaetan Burgio, Rita Ferreira, Zhi-Ping Feng, Cathryn M. Gould, Piyush B. Madhamshettiwar, Johan Flygare, Thomas J. Gonda, Kaylene J. Simpson, Ulrike Kutay, Richard B. Pearson, Christoph Engel, Nicholas J. Watkins, Ross D. Hannan, Amee J. George
Publikováno v:
Cell reports. 41(5)
The nucleolar surveillance pathway monitors nucleolar integrity and responds to nucleolar stress by mediating binding of ribosomal proteins to MDM2, resulting in p53 accumulation. Inappropriate pathway activation is implicated in the pathogenesis of
Autor:
Justine K. Lee, Ulrike Kutay, Sheren Al-Obaidi, Mei S. Wong, Priscilla Soo, Lorena Núñez-Villacís, Christian Montellese, Ross D. Hannan, Rita Ferreira, Kate M Parsons, Amee J George, Gaetan Burgio, Kaylene J. Simpson, Christoph Engel, Nicholas J. Watkins, Katherine M. Hannan, Tobias D. Williams, Johan Flygare, Cathryn M. Gould, Kira D. Wysoke, Maurits Evers, Zhi-Ping Feng, Thomas J. Gonda, Lorey K. Smith, Nadine Hein, Richard B. Pearson, Jeannine Diesch, Perlita Poh, Piyush B. Madhamshettiwar, Megan Pavy, Jin-Shu He
The nucleolar surveillance pathway (NSP) monitors nucleolar fidelity and responds to nucleolar stresses (i.e., inactivation of ribosome biogenesis) by mediating the inhibitory binding of ribosomal proteins (RPs) to mouse double minute 2 homolog (MDM2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27f004f573c723ed975ca1ebf9c31b2e
https://doi.org/10.1101/2021.01.21.427535
https://doi.org/10.1101/2021.01.21.427535
Autor:
Jin-Shu He, Antony W. Braithwaite, Ross D. Hannan, Antonio Musio, Kate M Parsons, Parry Guilford, Jisha Antony, Amee J George, Julia A. Horsfield, Anastasia Labudina, Gregory Gimenez, Sarada Ketharnathan, Chue Vin Chin, Maria Michela Pallotta
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
Mutations in genes encoding subunits of the cohesin complex are common in several cancers, but may also expose druggable vulnerabilities. We generated isogenic MCF10A cell lines with deletion mutations of genes encoding cohesin subunits SMC3, RAD21,
Autor:
Jisha Antony, Julia A. Horsfield, Kate M Parsons, Anastasia Labudina, Ross D. Hannan, Antonio Musio, Chue Vin Chin, Maria Michela Pallotta, Sarada Ketharnathan, Gregory Gimenez, Parry Guilford, Amee J George, Jin-Shu He, Antony W. Braithwaite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::931de0773dc69925b6e40553cbe953ab
https://doi.org/10.7554/elife.61405.sa2
https://doi.org/10.7554/elife.61405.sa2
Autor:
Thi H. O. Nguyen, Nicholas Coatsworth, Teresa Neeman, Jin-Shu He, Sarah M. Hicks, Florian Kurth, Kate M Parsons, Ian A. Cockburn, Hayley A. McNamara, Graham J. Mann, Carola G. Vinueas, Amee J George, Sidra A Ali, Samina Nazir, Kai Pohl, Elizabeth E. Gardiner, Louise C. Rowntree, Paul S. Myles, Leif E. Sander, Denise L. Doolan, Katherine Kedzierska, Matthew C. Cook, Russell L. Gruen
Estimates of seroprevalence of SARS-CoV-2 antibodies have been hampered by inadequate assay sensitivity and specificity. Using an ELISA-based approach to that combines data about IgG responses to both the Nucleocapsid and Spike-receptor binding domai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f86bf813793546366a6477bc775b3715
https://doi.org/10.1101/2020.09.09.20191031
https://doi.org/10.1101/2020.09.09.20191031
Autor:
Ross D. Hannan, Jin-Shu He, Amee J George, Kate M Parsons, Nadine Hein, Maurits Evers, Priscilla Soo, Katherine M. Hannan
Publikováno v:
ASSAY and Drug Development Technologies. 16:320-332
The nucleolus is a dynamic subnuclear compartment that has a number of different functions, but its primary role is to coordinate the production and assembly of ribosomes. For well over 100 years, pathologists have used changes in nucleolar number an