Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Kate Lauder"'
Autor:
Daniele Castagnolo, Kate Lauder
Publikováno v:
Lauder, K & Castagnolo, D 2020, ' Photo-Biocatalytic Cascades for the Synthesis of Volatile Sulfur Compounds and Chemical Building Blocks ', SYNLETT, vol. 31, no. 8, pp. 737-744 . https://doi.org/10.1055/s-0039-1690784
Biocatalysis is a branch of catalysis that exploits enzymes to perform highly stereoselective chemical transformations under mild and sustainable conditions. This Synpact highlights how biocatalysis can be used in the synthesis of chiral 1,3-mercapto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28e2926ac3963c2f6abff19dc5560430
https://doi.org/10.1055/s-0039-1690784
https://doi.org/10.1055/s-0039-1690784
Autor:
Fei Zhao, Kate Lauder, Siyu Liu, James D. Finnigan, Simon B. R. Charnock, Simon J. Charnock, Daniele Castagnolo
Publikováno v:
Angewandte Chemie (International ed. in English). 61(31)
Chiral β-hydroxysulfides are an important class of organic compounds which find broad application in organic and pharmaceutical chemistry. Herein we describe the development of novel biocatalytic and chemoenzymatic methods for the enantioselective s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aa4b5cc3e363c09c9b770f3c66de840
https://pubmed.ncbi.nlm.nih.gov/35576553
https://pubmed.ncbi.nlm.nih.gov/35576553
Autor:
Kate Lauder, Gary W. Black, Nicholas J. Turner, Aya Al Mekdad, Renzo Luisi, Daniele Castagnolo, Anita Toscani, Nicola Brown, Domiziana Masci
Publikováno v:
Organic & Biomolecular Chemistry. 17:8982-8986
A facile microwave assisted three-component protocol allows the synthesis of chiral aryl-1,2-mercaptoamines in water in a few minutes with high yields, bypassing the use of toxic aziridine intermediates. The chiral 1,2-mercaptoamines were then derace
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70016530d2392ee797523f1120fce5be
https://doi.org/10.1039/c9ob01962f
https://doi.org/10.1039/c9ob01962f
Publikováno v:
Chemistry (Weinheim an Der Bergstrasse, Germany)
The enantioselective synthesis of α‐thiocarboxylic acids by biocatalytic dynamic kinetic resolution (DKR) of nitrile precursors exploiting nitrilase enzymes is described. A panel of 35 nitrilase biocatalysts were screened and enzymes Nit27 and Nit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86591ff7a1ba0cacf954757bce5fc1e4
https://pubmed.ncbi.nlm.nih.gov/32239730
https://pubmed.ncbi.nlm.nih.gov/32239730
Autor:
Etienne Decroly, Suzanne J.F. Kaptein, Romano Silvestri, Johan Neyts, Bruno Canard, Carl Graham, Sharon Spizzichino, Giulio Mattedi, Daniele Castagnolo, Wahiba Aouadi, Coralie Valle, David J. Barlow, Zakary Sule, Kate Lauder
Publikováno v:
ChemMedChem
ChemMedChem, Wiley-VCH Verlag, 2020, 15 (4), pp.385-390. ⟨10.1002/cmdc.201900533⟩
ChemMedChem, 2020, 15 (4), pp.385-390. ⟨10.1002/cmdc.201900533⟩
Chemmedchem
ChemMedChem, Wiley-VCH Verlag, 2020, 15 (4), pp.385-390. ⟨10.1002/cmdc.201900533⟩
ChemMedChem, 2020, 15 (4), pp.385-390. ⟨10.1002/cmdc.201900533⟩
Chemmedchem
The recent outbreaks of Zika virus (ZIKV) infection worldwide make the discovery of novel antivirals against flaviviruses a research priority. This work describes the identification of novel inhibitors of ZIKV through a structure‐based virtual scre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1adf1f97c56e87b6c50f0009d8cb12d
https://hal.archives-ouvertes.fr/hal-02890596/document
https://hal.archives-ouvertes.fr/hal-02890596/document
Autor:
Simon J. Charnock, Anita Toscani, Krupa Korah, Daniele Castagnolo, Yuyin Qi, Jesmine Lim, Kate Lauder
Publikováno v:
Lauder, K, Toscani, A, Qi, Y, Lim, J, Charnock, S J, Korah, K & Castagnolo, D 2018, ' Photo-biocatalytic One-Pot Cascades for the Enantioselective Synthesis of 1,3-Mercaptoalkanol Volatile Sulfur Compounds ', ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 57, no. 20 . https://doi.org/10.1002/anie.201802135
The synthesis of enantiomerically pure 1,3-mercaptoalkanol volatile sulfur compounds through a one-pot photo-biocatalytic cascade reaction is described. Two new KRED biocatalysts with opposite enantioselectivity were discovered and proved to be effic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68595913d0d88b60c8beff8667ea2d29
https://doi.org/10.1002/ange.201802135
https://doi.org/10.1002/ange.201802135
Publikováno v:
Lauder, K, Toscani, A, Scalacci, N & Castagnolo, D 2017, ' Synthesis and Reactivity of Propargylamines in Organic Chemistry ', Chemical Reviews, vol. 117, no. 24, pp. 14091-14200 . https://doi.org/10.1021/acs.chemrev.7b00343
Propargylamines are a versatile class of compounds which find broad application in many fields of chemistry. This review aims to describe the different strategies developed so far for the synthesis of propargylamines and their derivatives as well as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::377897b9ee777cdbe0240d3657fe11a9
https://doi.org/10.1021/acs.chemrev.7b00343
https://doi.org/10.1021/acs.chemrev.7b00343
Autor:
Marcus C. Durrant, Kate Lauder, Anjana M. D. S. Delpe Acharige, Mark P. C. Brennan, Adesola O. Odebunmi, Fiona McMahon
During the red blood cell phase of their life cycle, malaria parasites digest their host's haemoglobin, with concomitant release of potentially toxic iron(iii) protoporphyrin IX (FePPIX). The parasites' strategy for detoxification of FePPIX involves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::435602d246b2837a934c22594e4ce34a
https://nrl.northumbria.ac.uk/id/eprint/38061/1/c8dt03369b.pdf
https://nrl.northumbria.ac.uk/id/eprint/38061/1/c8dt03369b.pdf