Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Kate Lansdell"'
Publikováno v:
European Journal of Surgical Oncology. 48:e237
Publikováno v:
European Journal of Surgical Oncology. 46:e18
Effects of the antiepileptic drugs lamotrigine, topiramate and gabapentin on hERG potassium currents
Publikováno v:
Epilepsy Research. 63:17-25
Drugs that inhibit the cardiac rapid delayed rectifier potassium ion current (I(Kr)) can be proarrhythmic and their clinical use has been associated with sudden unexpected death (SUD) due to cardiac arrhythmia. SUD is 20-40 times more common among pe
Publikováno v:
Epilepsy Research. 55:147-157
Drugs that inhibit the cardiac rapid delayed rectifier potassium ion current (IKr) channel can be proarrhythmic and their clinical use has been associated with sudden unexpected death (SUD). Since SUD is about 20 times more common among people with e
Publikováno v:
European journal of pharmacology. 510(1-2)
Trazodone has been associated with prolonged QT-interval and increased risk of polymorphous ventricular tachycardias clinically and has demonstrated in vitro inhibition of hERG (human ether-a-go-go-related gene) channel current. This study attempts t
Autor:
Junko Kimura, Hiroshi Mizuno, Yoshio Sawa, William David Kerns, Mamoru Saito, Hideyuki Adachi, Motoharu Kakiki, Kate Lansdell
Publikováno v:
Biologicalpharmaceutical bulletin. 26(12)
The aim of this study was to assess the cardiovascular effects of a selective phosphodiesterase 5 inhibitor ER-118585, 4-[(3-chloro-4-methoxybenzyl)amino]-1-(2-hydroxy-7-azaspiro[3.5]non-7-yl)-6-phthalazinecarbonitrile monohydrochloride. The present
Publikováno v:
Thorax. 65:A106-A107
Introduction Malignant mesothelioma (MM) is a cancer that most commonly arises within the pleura, and carries a poor prognosis. There is a strong association with past asbestos exposure so incidence varies across the UK. In the South West of the UK t
Publikováno v:
Journal of Thoracic Oncology. 2:S817