Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Kate L Osman"'
Autor:
Suzanne N King, Nada Kaissieh, Chandler Haxton, Marjan Shojaei, Luke Malott, Lekha Devara, Rebecca Thompson, Kate L Osman, Jessica Millward, Megan Blackburn, Teresa E Lever
Publikováno v:
PLoS ONE, Vol 18, Iss 6, p e0287044 (2023)
Swallowing impairment is a major complication of radiation treatment for oropharyngeal cancers. Developing targeted therapies that improve swallowing outcomes relies on an understanding of the mechanisms that influence motor function after radiation
Externí odkaz:
https://doaj.org/article/d74efc39f53542a79b9e2979b37782a6
Autor:
Erika R. Murphy, Rebecca Thompson, Kate L. Osman, Chandler Haxton, Margaret Brothers, Li Lee, Kristen Warncke, Catherine L. Smith, Amy N. Keilholz, Ali Hamad, Mojgan Golzy, Filiz Bunyak, Lixin Ma, Nicole L. Nichols, Teresa E. Lever
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
The tongue plays a crucial role in the swallowing process, and impairment can lead to dysphagia, particularly in motor neuron diseases (MNDs) resulting in hypoglossal-tongue axis degeneration (e.g., amyotrophic lateral sclerosis and progressive bulba
Externí odkaz:
https://doaj.org/article/42cced8f5f0544f0b16bc704e7fb0608
Autor:
Elijah D. Lowenstein, Pierre-Louis Ruffault, Aristotelis Misios, Kate L. Osman, Huimin Li, Rachel S. Greenberg, Rebecca Thompson, Kun Song, Stephan Dietrich, Xun Li, Nikita Vladimirov, Andrew Woehler, Jean-François Brunet, Niccolò Zampieri, Ralf Kühn, Stephen D. Liberles, Shiqi Jia, Gary R. Lewin, Nikolaus Rajewsky, Teresa E. Lever, Carmen Birchmeier
Vagal sensory neurons monitor mechanical and chemical stimuli in the gastrointestinal tract. Major efforts are underway to assign physiological functions to the many distinct subtypes of vagal sensory neurons. Here, we use genetically guided anatomic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87ba8278c17d81033e0193fd29f42d53
http://edoc.mdc-berlin.de/23368/1/23368oa.pdf
http://edoc.mdc-berlin.de/23368/1/23368oa.pdf
Autor:
Elijah D. Lowenstein, Pierre-Louis Ruffault, Aristotelis Misios, Kate L. Osman, Huimin Li, Rebecca Thompson, Kun Song, Stephan Dietrich, Xun Li, Nikita Vladimirov, Jean-François Brunet, Andrew Woehler, Niccolò Zampieri, Ralf Kühn, Shiqi Jia, Gary R. Lewin, Nikolaus Rajewsky, Teresa E. Lever, Carmen Birchmeier
SummarySensory neurons of the vagus nerve monitor distention and stretch in the gastrointestinal tract. Major efforts are underway to assign physiological functions to the many distinct subtypes of vagal sensory neurons. Here, we used genetically gui
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e6cf2d0215bda175f0e45c8bbd1d98b
https://doi.org/10.1101/2022.07.07.499111
https://doi.org/10.1101/2022.07.07.499111
Autor:
Brayton Ballenger, Elsie Barry, Jing Wang, Chandler Haxton, Ian Deninger, Rebecca Thompson, Kate L. Osman, Teresa E. Lever
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f6ab8caa8323917c94895fd990e45d3
https://doi.org/10.1096/fasebj.2022.36.s1.r4239
https://doi.org/10.1096/fasebj.2022.36.s1.r4239
Autor:
Marissa Mueller, Rebecca Thompson, Kate L. Osman, Ellyn Andel, Chandler A. DeJonge, Sophia Kington, Zola Stephenson, Ali Hamad, Filiz Bunyak, Nicole L. Nichols, Teresa E. Lever
Publikováno v:
Dysphagia
Current treatments for dysphagia in ALS do not target the underlying tongue weakness and denervation atrophy that is prevalent in spinal and bulbar ALS cases. To address this clinical gap, we studied the low copy number SOD1-G93A (LCN-SOD1) mouse mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d80bd533ee78675c9409f917cb65ce53
https://europepmc.org/articles/PMC9568622/
https://europepmc.org/articles/PMC9568622/
Autor:
Bridget L. Hopewell, Megan M Haney, Victoria Caywood, Teresa E. Lever, Brayton Ballenger, Aaron Thiessen, Marlena Szewczyk, Alexis Mok, Daniel Ohlhausen, Ian Deninger, Christopher Ian Newberry, Emily Leary, Jakob Allen, Kate L Osman, Bradford P. Zitsch
Publikováno v:
Dysphagia
Iatrogenic recurrent laryngeal nerve (RLN) injury is a morbid complication of anterior neck surgical procedures. Existing treatments are predominantly symptomatic, ranging from behavioral therapy to a variety of surgical approaches. Though laryngeal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5cf0ee029e60066ed5554aed750fcac
https://doi.org/10.1007/s00455-019-10045-6
https://doi.org/10.1007/s00455-019-10045-6
Autor:
Sabrina Kohlberg, Alexis Mok, Andries Ferreira, Joan R. Coates, Kate L Osman, Katelyn McCormack, Elizabeth A. Bearce, Matan D. Kadosh, Mary K. Fagan, Teresa E. Lever, Nicole L. Nichols, Lori A Lind, Ryan T. Brooks
Publikováno v:
Dysphagia
The goal of this study was to compare dysphagia phenotypes in low and high copy number (LCN and HCN) transgenic superoxide dismutase 1 (SOD1) mouse models of ALS to accelerate the discovery of novel and effective treatments for dysphagia and early am
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39107e97a8f1b727c9579dc86e9d9fc0
https://doi.org/10.1007/s00455-019-10034-9
https://doi.org/10.1007/s00455-019-10034-9
Autor:
Kate L Osman, Ian Deninger, Ellyn M Andel, Megan M Haney, Teresa E. Lever, Brayton Ballenger, Joseph R Sinnott, Kevin J. Cummings, Lori A. Thombs, Victoria Caywood, Alexis Mok
Publikováno v:
Otolaryngol Head Neck Surg
The intricate sensorimotor neural circuits that control swallowing are heavily reliant on serotonin (5-hydroxytryptamine [5-HT]); however, the impact of 5-HT deficiency on swallow function remains largely unexplored. We investigated this using mice d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::853414461cd1335ff8d01d3ed15e79e0
https://pubmed.ncbi.nlm.nih.gov/31035861
https://pubmed.ncbi.nlm.nih.gov/31035861
Autor:
Amy N. Keilholz, Ishan Pathak, Catherine L. Smith, Kate L. Osman, Lauren Smith, Grace Oti, Mojgan Golzy, Lixin Ma, Teresa E. Lever, Nicole L. Nichols
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
IntroductionTongue weakness and atrophy can lead to deficits in the vital functions of breathing and swallowing in patients with motor neuron diseases (MNDs; e.g., amyotrophic lateral sclerosis (ALS) and pseudobulbar palsy), often resulting in aspira
Externí odkaz:
https://doaj.org/article/bd704596fda541c590c6727ea41c2f81