Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Kate Heesom"'
Autor:
Frank Dickson Antwi, Tufaha Awad, Meghan Larin, Kate Heesom, Phil Lewis, Paul Reddell, Zaruhi Poghosyan, Sharon Dewitt, Ryan Moseley, Vera Knäuper
Publikováno v:
Cells, Vol 13, Iss 11, p 982 (2024)
Tigilanol tiglate (TT, also known as EBC-46) is a novel, plant-derived diterpene ester possessing anticancer and wound-healing properties. Here, we show that TT-evoked PKC-dependent S985 phosphorylation of the tyrosine kinase MET leads to subsequent
Externí odkaz:
https://doaj.org/article/b063e5e14f0d4f9c81d992bdcf3a437c
Autor:
Benjamin Clennell, Tom G.J. Steward, Kaliya Hanman, Tom Needham, Janette Benachour, Mark Jepson, Meg Elley, Nathan Halford, Kate Heesom, Eunju Shin, Elek Molnár, Bruce W. Drinkwater, Daniel J. Whitcomb
Publikováno v:
Brain Stimulation, Vol 16, Iss 2, Pp 540-552 (2023)
Background: Focused ultrasound stimulation (FUS) has the potential to provide non-invasive neuromodulation of deep brain regions with unparalleled spatial precision. However, the cellular and molecular consequences of ultrasound stimulation on neuron
Externí odkaz:
https://doaj.org/article/6cddc2561d5d435595f4962a56b3ee87
Autor:
Georgina Glover, Margaritis Voliotis, Urszula Łapińska, Brandon M. Invergo, Darren Soanes, Paul O’Neill, Karen Moore, Nela Nikolic, Peter G. Petrov, David S. Milner, Sumita Roy, Kate Heesom, Thomas A. Richards, Krasimira Tsaneva-Atanasova, Stefano Pagliara
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022)
The combined nutritional and salinity limitation is shown to increase glucose uptake and degradation rates in individual E. coli bacteria.
Externí odkaz:
https://doaj.org/article/2cd7bdb833f24378a636ee87d42a81d4
Autor:
Yvonne Naegelin, Jens Kuhle, Sabine Schädelin, Alexandre N. Datta, Stefano Magon, Michael Amann, Christian Barro, Gian Paolo Ramelli, Kate Heesom, Yves-Alain Barde, Peter Weber, Ludwig Kappos
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 16, Iss 1, Pp 1-9 (2021)
Abstract Background Rett syndrome (RS) is a severe neurodevelopmental disorder for which there is no approved therapy. This study aimed to assess safety and efficacy of oral fingolimod in children with RS using a pre-post and case–control design. M
Externí odkaz:
https://doaj.org/article/a3d1a388d4d84ef2a037ea1f987411e8
Autor:
Maho Yokoyama, Emily Stevens, Maisem Laabei, Leann Bacon, Kate Heesom, Sion Bayliss, Nicola Ooi, Alex J. O’Neill, Ewan Murray, Paul Williams, Anneke Lubben, Shaun Reeksting, Guillaume Meric, Ben Pascoe, Samuel K. Sheppard, Mario Recker, Laurence D. Hurst, Ruth C. Massey
Publikováno v:
Genome Biology, Vol 19, Iss 1, Pp 1-12 (2018)
Abstract Background Fitness costs imposed on bacteria by antibiotic resistance mechanisms are believed to hamper their dissemination. The scale of these costs is highly variable. Some, including resistance of Staphylococcus aureus to the clinically i
Externí odkaz:
https://doaj.org/article/162cfa4889354d5c9c2a89a796e7d357
Autor:
Chris Traylen, Sharada Ramasubramanyan, Jianmin Zuo, Martin Rowe, Rajaei Almohammad, Kate Heesom, Steve M. M. Sweet, David A. Matthews, Alison J. Sinclair
Publikováno v:
Pathogens, Vol 4, Iss 4, Pp 739-751 (2015)
The working model to describe the mechanisms used to replicate the cancer-associated virus Epstein-Barr virus (EBV) is partly derived from comparisons with other members of the Herpes virus family. Many genes within the EBV genome are homologous acro
Externí odkaz:
https://doaj.org/article/8878eaa160da42d2b779d53a9545209a
Publikováno v:
ERJ Open Research, Vol 3, Iss 3 (2017)
Bronchiectasis (BR) and smoking are risk factors for rheumatoid arthritis (RA) development. The mechanisms by which smoking and BR trigger RA are unknown, but are associated with concurrent rheumatoid factor (RF) and anti-cyclic citrullinated peptide
Externí odkaz:
https://doaj.org/article/411f599ad44c4c949a3de70c6053dc7a
Autor:
Ben Littlejohns, Philippe Pasdois, Simon Duggan, Andrew R Bond, Kate Heesom, Christopher L Jackson, Gianni D Angelini, Andrew P Halestrap, M-Saadeh Suleiman
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100579 (2014)
High-fat diet with obesity-associated co-morbidities triggers cardiac remodeling and renders the heart more vulnerable to ischemia/reperfusion injury. However, the effect of high-fat diet without obesity and associated co-morbidities is presently unk
Externí odkaz:
https://doaj.org/article/df9dab9275f54eb1904a4e874a09670a
Autor:
Tomer M. Yaron, Brook E. Heaton, Tyler M. Levy, Jared L. Johnson, Tristan X. Jordan, Benjamin M. Cohen, Alexander Kerelsky, Ting-Yu Lin, Katarina M. Liberatore, Danielle K. Bulaon, Samantha J. Van Nest, Nikos Koundouros, Edward R. Kastenhuber, Marisa N. Mercadante, Kripa Shobana-Ganesh, Long He, Robert E. Schwartz, Shuibing Chen, Harel Weinstein, Olivier Elemento, Elena Piskounova, Benjamin E. Nilsson-Payant, Gina Lee, Joseph D. Trimarco, Kaitlyn N. Burke, Cait E. Hamele, Ryan R. Chaparian, Alfred T. Harding, Aleksandra Tata, Xinyu Zhu, Purushothama Rao Tata, Clare M. Smith, Anthony P. Possemato, Sasha L. Tkachev, Peter V. Hornbeck, Sean A. Beausoleil, Shankara K. Anand, François Aguet, Gad Getz, Andrew D. Davidson, Kate Heesom, Maia Kavanagh-Williamson, David A. Matthews, Benjamin R. tenOever, Lewis C. Cantley, John Blenis, Nicholas S. Heaton
Publikováno v:
Science signaling, vol 15, iss 757
Multiple coronaviruses have emerged independently in the past 20 years that cause lethal human diseases. Although vaccine development targeting these viruses has been accelerated substantially, there remain patients requiring treatment who cannot be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99f52febef82f67d02ed9c0d55e48f84
https://escholarship.org/uc/item/44d513nc
https://escholarship.org/uc/item/44d513nc
Autor:
Safa Abdul‑Ghani, Katie Skeffington, Minjoo Kim, Marco Moscarelli, Philip Lewis, Kate Heesom, Francesca Fiorentino, Costanza Emanueli, Barnaby Reeves, Prakash Punjabi, Gianni Angelini, M-Saadeh Suleiman
Publikováno v:
Abdul-Ghani, S, Skeffington, K L, Kim, M, Moscarelli, M, Lewis, P A, Heesom, K J, Fiorentino, F, Emanueli, C, Reeves, B C, Punjabi, P, Angelini, G D & Suleiman, M-S 2022, ' Effect of cardioplegic arrest and reperfusion on left and right ventricular proteome/phosphoproteome in patients undergoing surgery for coronary or aortic valve disease ', International Journal of Molecular Medicine, vol. 49, no. 6, 77 . https://doi.org/10.3892/ijmm.2022.5133
Our earlier work has shown inter‑disease and intra‑disease differences in the cardiac proteome between right (RV) and left (LV) ventricles of patients with aortic valve stenosis (AVS) or coronary artery disease (CAD). Whether disease remodeling a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6779ebc999e58d43032278b910f02eac
https://research-information.bris.ac.uk/ws/files/321769496/ijmm_49_6_5133_PDF.pdf
https://research-information.bris.ac.uk/ws/files/321769496/ijmm_49_6_5133_PDF.pdf