Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Kate Hartland"'
Autor:
Yang Jiao, Umer Ahmed, M.F. Michelle Sim, Andrea Bejar, Xiaolan Zhang, M. Mesbah Uddin Talukder, Robert Rice, Jason Flannick, Anna I. Podgornaia, Dermot F. Reilly, Jesse M. Engreitz, Maria Kost-Alimova, Kate Hartland, Josep-Maria Mercader, Sara Georges, Vilas Wagh, Marija Tadin-Strapps, John G. Doench, J. Michael Edwardson, Justin J. Rochford, Evan D. Rosen, Amit R. Majithia
Publikováno v:
Molecular Metabolism, Vol 24, Iss , Pp 108-119 (2019)
Objective: Impaired expansion of peripheral fat contributes to the pathogenesis of insulin resistance and Type 2 Diabetes (T2D). We aimed to identify novel disease–gene interactions during adipocyte differentiation. Methods: Genes in disease-associ
Externí odkaz:
https://doaj.org/article/3a9d99e0cb264ba4a908d1ccdfe713f0
Autor:
Yi Li, Lina Wei, Marie-Charlotte Meinsohn, Rana Suliman, Maeva Chauvin, Jim Berstler, Kate Hartland, Mark M. Jensen, Natalie A. Sicher, Nicholas Nagykery, Patricia K. Donahoe, David Pepin
Publikováno v:
Proceedings of the National Academy of Sciences. 119
We identified the anti-Mullerian hormone (also known as Müllerian inhibiting substance or MIS) as an inhibitory hormone that induces long-term contraception in mammals. The type II receptor to this hormone, AMHR2 (also known as MISR2), represents a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f525aa6d19587dadd09ff6ef2d6b3e0
https://doi.org/10.1073/pnas.2122512119
https://doi.org/10.1073/pnas.2122512119
Autor:
Maria Kost-Alimova, Anne E. Carpenter, Kate Hartland, Aravind Subramanian, Beth A. Cimini, Ted Natoli, Marzieh Haghighi, Xiaodong Lu, Gregory P. Way, David J. Logan, Lev Litichevskiy, Niranj Chandrasekaran, Michael Bornholdt, Mohammad Hossein Rohban, Shantanu Singh, Adeniyi Adeboye, Juan C. Caicedo, Kyle W. Karhohs, Andrew Yang
Publikováno v:
Cell Systems. 13:911-923.e9
Deep profiling of cell states can provide a broad picture of biological changes that occur in disease, mutation, or in response to drug or chemical treatments. Morphological and gene expression profiling, for example, can cost-effectively capture tho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::156d5a36420dbff4586cc53ab7bd008e
https://doi.org/10.1016/j.cels.2022.10.001
https://doi.org/10.1016/j.cels.2022.10.001
Autor:
Josep-Maria Mercader, Jason Flannick, John G. Doench, M.F. Michelle Sim, J. Michael Edwardson, Kate Hartland, Sara A Georges, Dermot F. Reilly, Maria Kost-Alimova, Anna I. Podgornaia, Andrea Bejar, Vilas Wagh, Amit R. Majithia, Evan D. Rosen, Justin J. Rochford, Marija Tadin-Strapps, Yang Jiao, Jesse M. Engreitz, Xiaolan Zhang, Robert H. Rice, Mesbah Uddin Talukder, Umer Ahmed
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 24, Iss, Pp 108-119 (2019)
Molecular Metabolism, Vol 24, Iss, Pp 108-119 (2019)
Objective Impaired expansion of peripheral fat contributes to the pathogenesis of insulin resistance and Type 2 Diabetes (T2D). We aimed to identify novel disease–gene interactions during adipocyte differentiation. Methods Genes in disease-associat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f005658af400d94d686ecffbb138ea30
Autor:
Stuart L. Schreiber, Philip N. Moquist, Michelle Palmer, Louis DiDone, Jun Pu, Sivaraman Dandapani, Damian J. Krysan, Kate Hartland, Benito Munoz
Publikováno v:
ACS Infectious Diseases
Cryptococcus neoformans is one of the most important human fungal pathogens; however, no new therapies have been developed in over 50 years. Fungicidal activity is crucially important for an effective anticryptococal agent and, therefore, we screened
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc67c8bad144fc0b5f0432fa3cfb3beb
http://europepmc.org/articles/PMC4709821
http://europepmc.org/articles/PMC4709821
Autor:
Yuan Yuan, Kate Hartland, Etienne Sokal, Yikai Wang, Bridget K. Wagner, Young-kwon Kim, Cheng Zhong, Philippe A. Lysy, Nicola Tolliday, Stuart L. Schreiber, Zarko V. Boskovic, Deepika Walpita, Damian W. Young
Publikováno v:
Chemistry & Biology. 21(2)
SummaryPancreatic and duodenal homeobox 1 (PDX1), a member of the homeodomain-containing transcription factor family, is a key transcription factor important for both pancreas development and mature β cell function. The ectopic overexpression of Pdx
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d92217d9bea853607c304fde8d75cb6