Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Kate H Gartlan"'
Autor:
Annemiek B van Spriel, Mariam Sofi, Kate H Gartlan, Alie van der Schaaf, Ineke Verschueren, Ruurd Torensma, Reinier A P Raymakers, Bruce E Loveland, Mihai G Netea, Gosse J Adema, Mark D Wright, Carl G Figdor
Publikováno v:
PLoS Pathogens, Vol 5, Iss 3, p e1000338 (2009)
Immunoglobulin A (IgA) secretion by plasma cells in the immune system is critical for protecting the host from environmental and microbial infections. However, the molecular mechanisms underlying the generation of IgA(+) plasma cells remain poorly un
Externí odkaz:
https://doaj.org/article/2d710e37a74e4f89a83faca68b52c341
Autor:
Kate H. Gartlan, Motoko Koyama, Katie E. Lineburg, Karshing Chang, Kathleen S. Ensbey, Rachel D. Kuns, Andrea S. Henden, Luke D. Samson, Andrew D. Clouston, Angel F. Lopez, Kelli P.A. MacDonald, Geoffrey R. Hill
Publikováno v:
Blood Advances, Vol 3, Iss 19, Pp 2859-2865 (2019)
Abstract: Granulocyte-macrophage colony-stimulating factor (GM-CSF) has recently emerged as an important pathogenic cytokine in acute graft-versus-host disease (GVHD), but the nature of the T-cell lineages secreting the cytokine and the mechanisms of
Externí odkaz:
https://doaj.org/article/d76e1a4d6bf14802a597a6f718045478
Autor:
Kate H. Gartlan, Antiopi Varelias, Motoko Koyama, Renee J. Robb, Kate A. Markey, Karshing Chang, Andrew N. Wilkinson, David Smith, Md Ashik Ullah, Rachel D. Kuns, Neil C. Raffelt, Stuart D. Olver, Katie E. Lineburg, Bianca E. Teal, Melody Cheong, Michele W.L. Teng, Mark J. Smyth, Siok-Keen Tey, Kelli P.A. MacDonald, Geoffrey R. Hill
Publikováno v:
Blood Advances, Vol 1, Iss 6, Pp 341-351 (2017)
Abstract: T-helper 17 (Th17) cells have been widely implicated as drivers of autoimmune disease. In particular, Th17 cytokine plasticity and acquisition of an interleukin-17A+(IL-17A+)interferon γ(IFNγ)+ cytokine profile is associated with increase
Externí odkaz:
https://doaj.org/article/df05b8e5031c4704855ef42d306ae5c3
Autor:
Geoffrey R. Hill, Motoko Koyama, Mariapia A. Degli-Esposti, Joseph A. Trapani, Kelli P.A. MacDonald, Christian R. Engwerda, Mark J. Smyth, Glen M. Boyle, Kate A. Markey, Slavica Vuckovic, Antiopi Varelias, Greg Kelly, Vivien R. Sutton, Karshing Chang, Jose Paulo Martins, Christopher E. Andoniou, Rachel D. Kuns, Ping Zhang, Siok-Keen Tey, Jason S. Lee, Kate H. Gartlan, Melody Cheong
Supplementary Figure S1: GVHD survival of lethally-irradiated (day 0, 1000cGy split dose) B6.WT, B6.ASC-/- or B6.NLRP3-/- recipients transplanted with BALB/c BM (5x106) and T cells (5x106). The non-GVHD control group received TCD BM cells (5x106) onl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12c670406bdd6e90ec2d85cea9452ca1
https://doi.org/10.1158/2326-6066.22543108
https://doi.org/10.1158/2326-6066.22543108
Autor:
Geoffrey R. Hill, Motoko Koyama, Mariapia A. Degli-Esposti, Joseph A. Trapani, Kelli P.A. MacDonald, Christian R. Engwerda, Mark J. Smyth, Glen M. Boyle, Kate A. Markey, Slavica Vuckovic, Antiopi Varelias, Greg Kelly, Vivien R. Sutton, Karshing Chang, Jose Paulo Martins, Christopher E. Andoniou, Rachel D. Kuns, Ping Zhang, Siok-Keen Tey, Jason S. Lee, Kate H. Gartlan, Melody Cheong
The adaptor protein ASC (apoptosis-associated speck-like protein containing a CARD) is known to facilitate caspase-1 activation, which is essential for innate host immunity via the formation of the inflammasome complex, a multiprotein structure respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7145b9fd80a40cc0741b069c6d960d1
https://doi.org/10.1158/2326-6066.c.6550138.v1
https://doi.org/10.1158/2326-6066.c.6550138.v1
Autor:
Geoffrey R. Hill, Motoko Koyama, Mariapia A. Degli-Esposti, Joseph A. Trapani, Kelli P.A. MacDonald, Christian R. Engwerda, Mark J. Smyth, Glen M. Boyle, Kate A. Markey, Slavica Vuckovic, Antiopi Varelias, Greg Kelly, Vivien R. Sutton, Karshing Chang, Jose Paulo Martins, Christopher E. Andoniou, Rachel D. Kuns, Ping Zhang, Siok-Keen Tey, Jason S. Lee, Kate H. Gartlan, Melody Cheong
Supplementary Table S1 (related to Fig. 4A): (A) Ingenuity Pathway Analysis derived from the uncorrected dataset displaying top canonical signaling pathways involving differentially regulated genes in recipients as described in Fig.4A. (B) 10 selecte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b81f04af8f07416c8522368ebdbf6e4
https://doi.org/10.1158/2326-6066.22543105.v1
https://doi.org/10.1158/2326-6066.22543105.v1
Autor:
Geoffrey R. Hill, Steven W. Lane, Mariapia A. Degli-Esposti, Thomas Brocker, Gabrielle T. Belz, Raymond J. Steptoe, Mark J. Smyth, Motoko Koyama, Melody Cheong, Simone A. Minnie, Andrea S. Henden, J. Paulo Martins, Renee J. Robb, Kate H. Gartlan, Daniel J. Browne, Rachel D. Kuns, Kate A. Markey
Supplementary table 1: Supplementary Table 1: Gene expression measured in QIAGEN Apoptosis Array; Supplementary Table 2: Antibodies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::042dfc3f266b06f081aef1749f01cb6a
https://doi.org/10.1158/1078-0432.22464882.v1
https://doi.org/10.1158/1078-0432.22464882.v1
Autor:
Siok-Keen Tey, Geoffrey R. Hill, Cameron I. Curley, A. James Morton, Glen A. Kennedy, Gary R. Pratt, Cheryl Hutchins, Devika Ganesamoorthy, Lachlan J. Coin, Michael P. Brown, Tessa Gargett, Judy Avery, Nienke Zomerdijk, Elise Sturgeon, Luke D. Samson, Stuart D. Olver, Kate H. Gartlan, Antiopi Varelias, Raymond Au, Md Ashik Ullah, Jyothy Raju, Ping Zhang
Supplemental Material
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61dce7f3501497710be1558e6ff443ae
https://doi.org/10.1158/1078-0432.22474131.v1
https://doi.org/10.1158/1078-0432.22474131.v1
Autor:
Siok-Keen Tey, Geoffrey R. Hill, Cameron I. Curley, A. James Morton, Glen A. Kennedy, Gary R. Pratt, Cheryl Hutchins, Devika Ganesamoorthy, Lachlan J. Coin, Michael P. Brown, Tessa Gargett, Judy Avery, Nienke Zomerdijk, Elise Sturgeon, Luke D. Samson, Stuart D. Olver, Kate H. Gartlan, Antiopi Varelias, Raymond Au, Md Ashik Ullah, Jyothy Raju, Ping Zhang
Purpose:Inducible caspase 9 (iCasp9) is a cellular safety switch that can make T-cell therapy safer. The purpose of this phase I trial was to investigate the use of iCasp9-transduced T-cell addback in adult patients undergoing haploidentical stem cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07c44c90e4fc94038c1bb12ce74abe40
https://doi.org/10.1158/1078-0432.c.6528696.v1
https://doi.org/10.1158/1078-0432.c.6528696.v1
Autor:
Geoffrey R. Hill, Steven W. Lane, Mariapia A. Degli-Esposti, Thomas Brocker, Gabrielle T. Belz, Raymond J. Steptoe, Mark J. Smyth, Motoko Koyama, Melody Cheong, Simone A. Minnie, Andrea S. Henden, J. Paulo Martins, Renee J. Robb, Kate H. Gartlan, Daniel J. Browne, Rachel D. Kuns, Kate A. Markey
Purpose: Allogeneic bone marrow transplantation (BMT) provides curative therapy for leukemia via immunologic graft-versus-leukemia (GVL) effects. In practice, this must be balanced against life threatening pathology induced by graft-versus-host disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2311323d00efc28d48e4bbf248a1df81
https://doi.org/10.1158/1078-0432.c.6525849.v1
https://doi.org/10.1158/1078-0432.c.6525849.v1