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Autor:
Kate Fodor, Akira Kinoshita, Baoli Yang, Arianna L. Smith, Youssef A. Kousa, Brian C. Schutte
Publikováno v:
genesis. 55:e23038
Interferon Regulatory Factor 6 (IRF6) is a critical regulator of differentiation, proliferation and migration of keratinocytes. Mutations in IRF6 cause two autosomal dominant disorders characterized by cleft lip with or without cleft palate. In addit