Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Kate E. Foley"'
Autor:
Kate E. Foley, Donna M. Wilcock
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
The targeting of amyloid-beta (Aβ) plaques therapeutically as one of the primary causes of Alzheimer’s disease (AD) dementia has been an ongoing effort spanning decades. While some antibodies are extremely promising and have been moved out of clin
Externí odkaz:
https://doaj.org/article/ef7b32b7df0b4620ae84eca716092d46
Publikováno v:
Molecular Neurodegeneration, Vol 18, Iss 1, Pp 1-3 (2023)
Externí odkaz:
https://doaj.org/article/3368cacf9be5426bb9f757462b81c540
Autor:
Kate E. Foley, Amanda A. Hewes, Dylan T. Garceau, Kevin P. Kotredes, Gregory W. Carter, Michael Sasner, Gareth R. Howell
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
IntroductionRestrictions on existing APOE mouse models have impacted research toward understanding the strongest genetic risk factor contributing to Alzheimer’s disease (AD) and dementia, APOEε4, by hindering observation of a key, common genotype
Externí odkaz:
https://doaj.org/article/16f49bfb7bd8496bb1e3d17d7297f768
Autor:
Harriet M. Jackson, Kate E. Foley, Rita O’Rourke, Timothy M. Stearns, Dina Fathalla, B. Paul Morgan, Gareth R. Howell
Publikováno v:
BMC Genetics, Vol 21, Iss 1, Pp 1-16 (2020)
Abstract Background The complement cascade is increasingly implicated in development of a variety of diseases with strong immune contributions such as Alzheimer’s disease and Systemic Lupus Erythematosus. Mouse models have been used to determine fu
Externí odkaz:
https://doaj.org/article/614e55b302c34685b237b64274f950f7
Autor:
Kevin P. Kotredes, Adrian Oblak, Ravi S. Pandey, Peter Bor-Chian Lin, Dylan Garceau, Harriet Williams, Asli Uyar, Rita O'Rourke, Sarah O'Rourke, Cynthia Ingraham, Daria Bednarczyk, Melisa Belanger, Zackary Cope, Kate E. Foley, Benjamin A. Logsdon, Lara M. Mangravite, Stacey J. Sukoff Rizzo, Paul R. Territo, Gregory W. Carter, Michael Sasner, Bruce T. Lamb, Gareth R. Howell
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Externí odkaz:
https://doaj.org/article/e82314194efb4e0cb333030d27dfb73d
Autor:
Kate E. Foley, Cory A. Diemler, Amanda A. Hewes, Dylan T. Garceau, Michael Sasner, Gareth R. Howell
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 8, Iss 1, Pp n/a-n/a (2022)
Abstract Introduction Apolipoprotein E (APOE) ε4 is the strongest genetic risk factor for Alzheimer's disease and related dementias (ADRDs), affecting many different pathways that lead to cognitive decline. Exercise is one of the most widely propose
Externí odkaz:
https://doaj.org/article/dcd697927eed453f8598e777194b09ac
Autor:
Kevin P. Kotredes, Adrian Oblak, Ravi S. Pandey, Peter Bor-Chian Lin, Dylan Garceau, Harriet Williams, Asli Uyar, Rita O’Rourke, Sarah O’Rourke, Cynthia Ingraham, Daria Bednarczyk, Melisa Belanger, Zackary Cope, Kate E. Foley, Benjamin A. Logsdon, Lara M. Mangravite, Stacey J. Sukoff Rizzo, Paul R. Territo, Gregory W. Carter, Michael Sasner, Bruce T. Lamb, Gareth R. Howell
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Late-onset Alzheimer’s disease (AD; LOAD) is the most common human neurodegenerative disease, however, the availability and efficacy of disease-modifying interventions is severely lacking. Despite exceptional efforts to understand disease progressi
Externí odkaz:
https://doaj.org/article/73c95daef488457a898befbeee08ddc2
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-14 (2019)
Abstract Background The incidence of dementia and cognitive decline is increasing with no therapy or cure. One of the reasons treatment remains elusive is because there are various pathologies that contribute to age-related cognitive decline. Specifi
Externí odkaz:
https://doaj.org/article/3449a7a91dc84316826634288649313d
Autor:
Anthony C. Fiumera, Pamela C. Lovejoy, Kate E. Foley, Melissa M. Conti, Samantha M. Meadows, Christopher Bishop
Publikováno v:
Molecular Ecology. 30:2040-2053
Toxicant resistance is a complex trait, affected both by genetics and the environment. Like most complex traits, it can exhibit sexual dimorphism, yet sex is often overlooked as a factor in studies of toxicant resistance. Paraquat, one such toxicant,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c70907c2967ea474ae89a70a555ab868
https://doi.org/10.1111/mec.15878
https://doi.org/10.1111/mec.15878
Autor:
Kate E. Foley, Cory A. Diemler, Amanda A. Hewes, Dylan T. Garceau, Michael Sasner, Gareth R. Howell
INTRODUCTIONAPOEε4 is the strongest genetic risk factor for Alzheimer’s disease and related dementias (ADRDs) affecting many different pathways that lead to cognitive decline. Exercise is one of the most widely proposed prevention, and interventio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e7d7ee918a8386cfc69fbaedd742aa7
https://doi.org/10.1101/2022.03.01.480612
https://doi.org/10.1101/2022.03.01.480612
