Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kate E, Royle"'
Publikováno v:
Synthetic and Systems Biotechnology, Vol 3, Iss 1, Pp 64-75 (2018)
Adaptation allows organisms to maintain a constant internal environment, which is optimised for growth. The unfolded protein response (UPR) is an example of a feedback loop that maintains endoplasmic reticulum (ER) homeostasis, and is characteristic
Externí odkaz:
https://doaj.org/article/946be861930b44bb94f3bfa50fb457f3
Publikováno v:
Synthetic and Systems Biotechnology, Vol 3, Iss 1, Pp 64-75 (2018)
Adaptation allows organisms to maintain a constant internal environment, which is optimised for growth. The unfolded protein response (UPR) is an example of a feedback loop that maintains endoplasmic reticulum (ER) homeostasis, and is characteristic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c61d43f7d1090a977a1aaafc4f788d36
http://hdl.handle.net/10044/1/56668
http://hdl.handle.net/10044/1/56668
Publikováno v:
Synthetic and systems biotechnology. 3(1)
Adaptation allows organisms to maintain a constant internal environment, which is optimised for growth. The unfolded protein response (UPR) is an example of a feedback loop that maintains endoplasmic reticulum (ER) homeostasis, and is characteristic
Publikováno v:
Drug Discovery Today. 18:1250-1255
Despite decades of clinical and commercial success, the current paradigm for drug discovery and development is still empirical and costly. The many hundreds of therapeutic proteins (TPs) in the development pipeline and the FDA-led quality-by-design i
Autor:
Cleo Kontoravdi, Kate E. Royle
Publikováno v:
Biotechnology letters. 35(12)
The vast number of expression hosts available for recombinant protein production have a variety of advantages and disadvantages; none, however, is globally optimal and host selection is frequently a compromise. Strain development requires a holistic