Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Kate D Ryman"'
Publikováno v:
PLoS Pathogens, Vol 12, Iss 7, p e1005786 (2016)
A gold standard of antiviral vaccination has been the safe and effective live-attenuated 17D-based yellow fever virus (YFV) vaccines. Among more than 500 million vaccinees, only a handful of cases have been reported in which vaccinees developed a vir
Externí odkaz:
https://doaj.org/article/673e81f7346e4d449cae3e4bf2dbd3ea
Autor:
Christina L Gardner, Jozef Hritz, Chengqun Sun, Dana L Vanlandingham, Timothy Y Song, Elodie Ghedin, Stephen Higgs, William B Klimstra, Kate D Ryman
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 2, p e2719 (2014)
Mosquito-borne chikungunya virus (CHIKV) is a positive-sense, single-stranded RNA virus from the genus Alphavirus, family Togaviridae, which causes fever, rash and severe persistent polyarthralgia in humans. Since there are currently no FDA licensed
Externí odkaz:
https://doaj.org/article/bd01950fdf944de7be1a383c6be4f8b4
Autor:
Kathryn C Meier, Christina L Gardner, Mikhail V Khoretonenko, William B Klimstra, Kate D Ryman
Publikováno v:
PLoS Pathogens, Vol 5, Iss 10, p e1000614 (2009)
Mosquito-borne yellow fever virus (YFV) causes highly lethal, viscerotropic disease in humans and non-human primates. Despite the availability of efficacious live-attenuated vaccine strains, 17D-204 and 17DD, derived by serial passage of pathogenic Y
Externí odkaz:
https://doaj.org/article/e3344edea59c4fedadf8e03f6df650d5
Autor:
Christopher M. Weiss, Derek W. Trobaugh, Chengqun Sun, Tiffany M. Lucas, Michael S. Diamond, Kate D. Ryman, William B. Klimstra
Publikováno v:
mSphere, Vol 3, Iss 5 (2018)
ABSTRACT Type I interferon (IFN)-stimulated genes (ISGs) have critical roles in inhibiting virus replication and dissemination. Despite advances in understanding the molecular basis of ISG restriction, the antiviral mechanisms of many remain unclear.
Externí odkaz:
https://doaj.org/article/a2287e9b9d7344b2a42e47c800dea8d0
Autor:
Whitney C. Lane, Matthew D. Dunn, Christina L. Gardner, L. K. Metthew Lam, Alan M. Watson, Amy L. Hartman, Kate D. Ryman, William B. Klimstra
Publikováno v:
mBio, Vol 9, Iss 2 (2018)
ABSTRACT Interferon alpha/beta (IFN-α/β) is a critical mediator of protection against most viruses, with host survival frequently impossible in its absence. Many studies have investigated the pathways involved in the induction of IFN-α/β after vi
Externí odkaz:
https://doaj.org/article/3f78f74c9de64ce7adeb89adcf60c60b
Autor:
Kate D. Ryman, William B. Klimstra, Derek W. Trobaugh, Michael S. Diamond, Chengqun Sun, Christopher Weiss, Tiffany M. Lucas
Publikováno v:
mSphere, Vol 3, Iss 5 (2018)
mSphere, Vol 3, Iss 5, p e00209-18 (2018)
mSphere, Vol 3, Iss 5, p e00209-18 (2018)
Type I interferon (IFN)-stimulated genes (ISGs) have critical roles in inhibiting virus replication and dissemination. Despite advances in understanding the molecular basis of ISG restriction, the antiviral mechanisms of many remain unclear. The 20-k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c9c97ec0a23b510039d78ea0d3dcb79
https://pubmed.ncbi.nlm.nih.gov/30232164
https://pubmed.ncbi.nlm.nih.gov/30232164
Publikováno v:
npj Vaccines, Vol 3, Iss 1, Pp 1-10 (2018)
NPJ Vaccines
NPJ Vaccines
Live attenuated viruses are historically among the most effective viral vaccines. Development of a safe vaccine requires the virus to be less virulent, a phenotype that is historically arrived by empirical evaluation often leaving the mechanisms of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b15e8f32a2714bb4ce0fd08f163d77c
https://doi.org/10.1038/s41541-017-0039-z
https://doi.org/10.1038/s41541-017-0039-z
Autor:
Eddie Sullivan, Thomas C. Luke, William B. Klimstra, Jin-an Jiao, Hua Wu, Kate D. Ryman, Kanakatte Raviprakash, Chengqun Sun, Christina L. Gardner, Douglas S. Reed
Publikováno v:
Journal of Virology
Venezuelan equine encephalitis virus (VEEV) is a mosquito-borne RNA virus that causes low mortality but high morbidity rates in humans. In addition to natural outbreaks, there is the potential for exposure to VEEV via aerosolized virus particles. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65ab261f57dc3f8d246b4203c1a0122a
https://doi.org/10.1128/jvi.00226-17
https://doi.org/10.1128/jvi.00226-17
Autor:
Kate D. Ryman, Simon M. Barratt-Boyes, Simon C. Watkins, Parichat Duangkhae, Ernesto T. A. Marques, Louis D. Falo, Geza Erdos
Publikováno v:
The Journal of investigative dermatology. 138(3)
The skin is the site of dengue virus (DENV) transmission following the bite of an infected mosquito, but the contribution of individual cell types within skin to infection is unknown. We studied the dynamics of DENV infection in human skin explants u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0bb8aa34ff532b8534cd94d06500447
https://pubmed.ncbi.nlm.nih.gov/29106931
https://pubmed.ncbi.nlm.nih.gov/29106931
Publikováno v:
Journal of Virology. 88:2035-2046
Engineered alphavirus vectors expressing reporters of infection have been used for a number of years due to their relatively low costs for analysis of virus replication and the capacity to utilize imaging systems for longitudinal measurements of grow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8784ecfc5e7a8f44268563cbbbcb8a8f
https://doi.org/10.1128/jvi.02990-13
https://doi.org/10.1128/jvi.02990-13