Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Kate D, Meyer"'
Autor:
Matthew Tegowski, Kate D. Meyer
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
A major mechanism of post-transcriptional RNA regulation in cells is the addition of chemical modifications to RNA nucleosides, which contributes to nearly every aspect of the RNA life cycle. N6-methyladenosine (m6A) is a highly prevalent modificatio
Externí odkaz:
https://doaj.org/article/fcc658d03be14e6b9eaa26a8f4c905a5
Autor:
Sung-Min Lee, Bonsang Koo, Clément Carré, André Fischer, Chuan He, Ajeet Kumar, Kathy Liu, Kate D. Meyer, Guo-li Ming, Junmin Peng, Jean-Yves Roignant, Erik Storkebaum, Shuying Sun, Davide De Pietri Tonelli, Yinsheng Wang, Yi-Lan Weng, Luigi Pulvirenti, Yanhong Shi, Ki-Jun Yoon, Hongjun Song
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Increasing evidence reinforces the essential function of RNA modifications in development and diseases, especially in the nervous system. RNA modifications impact various processes in the brain, including neurodevelopment, neurogenesis, neuroplastici
Externí odkaz:
https://doaj.org/article/b324500bfd034a9b89490eedec6f532c
Autor:
Cassandra Catacalos, Alexander Krohannon, Sahiti Somalraju, Kate D Meyer, Sarath Chandra Janga, Kausik Chakrabarti
Publikováno v:
PLoS Pathogens, Vol 18, Iss 12, p e1010972 (2022)
"Epitranscriptomics" is the new RNA code that represents an ensemble of posttranscriptional RNA chemical modifications, which can precisely coordinate gene expression and biological processes. There are several RNA base modifications, such as N6-meth
Externí odkaz:
https://doaj.org/article/a37756c3a40345f0902866631a78261b
Autor:
Matthew Tegowski, Kate D. Meyer
Publikováno v:
STAR Protocols, Vol 3, Iss 3, Pp 101646- (2022)
Summary: Most techniques for mapping m6A-methylated RNAs transcriptome-wide require large amounts of RNA and have been limited to bulk cells and tissues. Here, we provide a detailed protocol for the identification of m6A sites in single HEK293T cells
Externí odkaz:
https://doaj.org/article/17f6131cef354fb8853d28ba38be0c29
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
N6-methyladenosine (m6A) is a critical regulator of gene expression and cellular function. Much of our knowledge of m6A has been enabled by the identification of m6A sites transcriptome-wide. However, global m6A profiling methods require high amounts
Externí odkaz:
https://doaj.org/article/0f81920c3e884532b86279f4778e9b0f
Autor:
Bei Liu, Dawn K. Merriman, Seung H. Choi, Maria A. Schumacher, Raphael Plangger, Christoph Kreutz, Stacy M. Horner, Kate D. Meyer, Hashim M. Al-Hashimi
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
N 6-Methyladenosine (m6A) is a post-transcriptional RNA modification that modulates RNA structure through a destabilization of m6A base pairing. Here the authors use NMR and UV melting experiments and show that m6A can also stabilize m6A–U base pai
Externí odkaz:
https://doaj.org/article/372622a59f9c424c8a4a6aac13ebbfc3
Publikováno v:
Annual Review of Biochemistry. 92
Over the past decade, mRNA modifications have emerged as important regulators of gene expression control in cells. Fueled in large part by the development of tools for detecting RNA modifications transcriptome wide, researchers have uncovered a diver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c48460030ed1fc0f1972abb18711cc69
https://doi.org/10.1146/annurev-biochem-052521-035330
https://doi.org/10.1146/annurev-biochem-052521-035330
Autor:
Mark A. Rubin, Samie R. Jaffrey, Salvatore Piscuoglio, Kate D. Meyer, Philip Rubin, Nadine Uebersax, John Gallon, Kellie A. Cotter
Supplementary Data 1. Number of m6A sites identified by miCLIP in LNCaP cells Supplementary Data 2. Number of m6A sites identified by miCLIP in RWPE cells Supplementary Data 3. Differentially expressed proteins (adjusted P-value < 0.05) with METTL3 k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a98f68d170c0123639d82f699dd60599
https://doi.org/10.1158/1541-7786.22526247
https://doi.org/10.1158/1541-7786.22526247
Autor:
Mark A. Rubin, Samie R. Jaffrey, Salvatore Piscuoglio, Kate D. Meyer, Philip Rubin, Nadine Uebersax, John Gallon, Kellie A. Cotter
Supplementary Figure 1. Association between m6A "writer", "eraser", and "reader" proteins and markers of advanced-stage disease. Supplementary Figure 2. Relation of miCLIP results to transcript length and expression. Supplementary Figure 3. Reversibl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::259de0a6d46daa1ce5492158e7098c43
https://doi.org/10.1158/1541-7786.22526244
https://doi.org/10.1158/1541-7786.22526244
Autor:
Mark A. Rubin, Samie R. Jaffrey, Salvatore Piscuoglio, Kate D. Meyer, Philip Rubin, Nadine Uebersax, John Gallon, Kellie A. Cotter
Recent evidence has highlighted the role of N6-methyladenosine (m6A) in the regulation of mRNA expression, stability, and translation, supporting a potential role for posttranscriptional regulation mediated by m6A in cancer. Here, we explore prostate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29cc332d56fb25c9af976d3e89833394
https://doi.org/10.1158/1541-7786.c.6545040.v1
https://doi.org/10.1158/1541-7786.c.6545040.v1