Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Kate Crump"'
Autor:
Dapeng Zhang, Huiling Xiong, Jan A Mennigen, Jason T Popesku, Vicki L Marlatt, Christopher J Martyniuk, Kate Crump, Andrew R Cossins, Xuhua Xia, Vance L Trudeau
Publikováno v:
PLoS ONE, Vol 4, Iss 6, p e5816 (2009)
BACKGROUND:Many vertebrates, including the goldfish, exhibit seasonal reproductive rhythms, which are a result of interactions between external environmental stimuli and internal endocrine systems in the hypothalamo-pituitary-gonadal axis. While it i
Externí odkaz:
https://doaj.org/article/c35b8eb0fc334676b57e9dbd412ad3e2
Autor:
Jennifer Watt, Thomas W. Moon, Kate Crump, Susanna K. Atkinson, Linda Jewell, Vance L. Trudeau, Christopher J. Martyniuk, J.P. Sherry, Vicki L. Marlatt, Josh Lakoff, Jules M. Blais
Publikováno v:
Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology. 156:92-101
This research examined the gene expression profile of three goldfish estrogen receptor (ER) subtypes in multiple tissues in relation to mRNA levels of aromatase B and vitellogenin (VTG) following waterborne estrogen exposures. The protocol consisted
Autor:
Christopher J. Martyniuk, Vance L. Trudeau, Andrew R. Cossins, Huiling Xiong, Jason T. Popesku, Hymie Anisman, Xuhua Xia, Jan A. Mennigen, E Zhao, Kate Crump
Publikováno v:
Physiological Genomics. 35:273-282
We investigated the effects of fluoxetine, a selective serotonin reuptake inhibitor, on neuroendocrine function and the reproductive axis in female goldfish. Fish were given intraperitoneal injections of fluoxetine twice a week for 14 days, resulting
Publikováno v:
Pharmaceutical Biology. 46:72-81
The pharmacological activity of neuroactive phytochemicals on recombinant human glutamic acid decarboxylase 65 (hGAD65) was investigated. GAD catalyzes the conversion of glutamic acid to γ-aminobutyric acid (GABA), which acts as an important inhibit
Publikováno v:
General and Comparative Endocrinology. 146:100-107
Secretoneurin (SN) is a 33-34 amino acid neuropeptide derived by endoproteolysis of secretogranin-II (SgII), a chromogranin. A multi-antigenic strategy was used to generate a rabbit polyclonal goldfish SN antiserum that was characterized for Western
Autor:
Satomi Kohno, Caren C. Helbing, Louis J. Guillette, Yue Song, Dieldrich S. Bermudez, Teresa A. Bryan, Juan Ausió, Nik Veldhoen, Carmen M. Bailey, Kate Crump
Publikováno v:
Comparative biochemistry and physiology. Part B, Biochemistrymolecular biology. 146(2)
Inhibitor of growth 2 (ING2) belongs to a family of tumor suppressors that are important regulators of a wide range of cellular processes including proliferation, apoptosis, and DNA repair. ING family members are found in yeast, plants, invertebrates
Publikováno v:
General and comparative endocrinology. 154(1-3)
During metamorphosis, the tadpole neuroendocrine brain is a major target for the organisational effects of hormones acting via both endocrine feedback mechanisms and local hormone production. While the receptor-mediated actions of thyroid hormones in
Autor:
Xuhua Xia, Emily R. Gerrie, Vance L. Trudeau, Kate Crump, Suzanne Chiu, Ashlie Nadler, Christopher J. Martyniuk, Huiling Xiong, Ravinder Sardana
Publikováno v:
Physiological genomics. 27(3)
17-α Ethinylestradiol (EE2), a pharmaceutical estrogen, is detectable in water systems worldwide. Although studies report on the effects of xenoestrogens in tissues such as liver and gonad, few studies to date have investigated the effects of EE2 in
Autor:
Carmen M. Bailey, Louis J. Guillette, Kate Crump, Teresa A. Bryan, Dieldrich S. Bermudez, Nik Veldhoen, Satomi Kohno, Caren C. Helbing
Publikováno v:
General and comparative endocrinology. 149(2)
Thyroid hormones (THs) play key regulatory roles in growth, development and metabolism in vertebrates. Modulation of the cellular hormonal response is largely through the activity of two nuclear TH receptors, TRalpha and TRbeta, which act as transcri
Autor:
Vance L. Trudeau, Kate Crump
Publikováno v:
Environmental Toxicology and Chemistry. 28:895
Mercury is a potent neurotoxin, and increasing levels have led to concern for human and wildlife health in many regions of the world. During the past three decades, studies in fish have examined the effects of sublethal mercury exposure on a range of