Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Kate Choi"'
Autor:
Nina E. Weisser, Mario Sanches, Eric Escobar-Cabrera, Jason O’Toole, Elizabeth Whalen, Peter W. Y. Chan, Grant Wickman, Libin Abraham, Kate Choi, Bryant Harbourne, Antonios Samiotakis, Andrea Hernández Rojas, Gesa Volkers, Jodi Wong, Claire E. Atkinson, Jason Baardsnes, Liam J. Worrall, Duncan Browman, Emma E. Smith, Priya Baichoo, Chi Wing Cheng, Joy Guedia, Sohyeong Kang, Abhishek Mukhopadhyay, Lisa Newhook, Anders Ohrn, Prajwal Raghunatha, Matteo Zago-Schmitt, Joseph D. Schrag, Joel Smith, Patricia Zwierzchowski, Joshua M. Scurll, Vincent Fung, Sonia Black, Natalie C. J. Strynadka, Michael R. Gold, Leonard G. Presta, Gordon Ng, Surjit Dixit
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
The success of HER2-targeted cancer therapy is limited by treatment resistance. Here, the authors engineer an anti-HER2 biparatopic antibody with multiple mechanisms of action including induction of HER2 clustering to trigger complement dependent cyt
Externí odkaz:
https://doaj.org/article/8a871ad93e594eeba832492229b1329b
Autor:
Abhishek Bedi, Kate Choi, Connor Keane, Madison Bolger-Munro, Ashley R. Ambrose, Michael R. Gold
Publikováno v:
Cells, Vol 12, Iss 23, p 2704 (2023)
B cell antigen receptor (BCR) signaling induces actin cytoskeleton remodeling by stimulating actin severing, actin polymerization, and the nucleation of branched actin networks via the Arp2/3 complex. This enables B cells to spread on antigen-bearing
Externí odkaz:
https://doaj.org/article/44948d1e7c1244329765c77597acb64d
Publikováno v:
Demographic Research, Vol 48, p 18 (2023)
Background: Rising median age at marriage and increasing lifestyle differentials across occupations suggest that occupations increasingly offer important signals of the economic and cultural resources of potential spouses. Scant attention has been pa
Externí odkaz:
https://doaj.org/article/5b9f9b680413403da9c57293deebe004
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Signaling by the B cell antigen receptor (BCR) initiates actin remodeling. The assembly of branched actin networks that are nucleated by the Arp2/3 complex exert outward force on the plasma membrane, allowing B cells to form membrane protrusions that
Externí odkaz:
https://doaj.org/article/f2c8cf382449494bbfc4e48ce3da7c54
Autor:
Madison Bolger-Munro, Kate Choi, Faith Cheung, Yi Tian Liu, May Dang-Lawson, Nikola Deretic, Connor Keane, Michael R. Gold
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
When B cells encounter membrane-bound antigens, the formation and coalescence of B cell antigen receptor (BCR) microclusters amplifies BCR signaling. The ability of B cells to probe the surface of antigen-presenting cells (APCs) and respond to APC-bo
Externí odkaz:
https://doaj.org/article/e9004ca4e69f462481ed809a38b90124
Publikováno v:
Demographic Research, Vol 46, p 33 (2022)
Background: Barriers to intermarriage are more formidable than barriers to interracial cohabitation. Relative to same-race couples, a higher share of interracial couples cohabits with their nonmarital partners. This raises the question: Does the soci
Externí odkaz:
https://doaj.org/article/66b335eb7db741ecaea523e72d2442e9
Autor:
Madison Bolger-Munro, Kate Choi, Joshua M Scurll, Libin Abraham, Rhys S Chappell, Duke Sheen, May Dang-Lawson, Xufeng Wu, John J Priatel, Daniel Coombs, John A Hammer, Michael R Gold
Publikováno v:
eLife, Vol 8 (2019)
When B cells encounter antigens on the surface of an antigen-presenting cell (APC), B cell receptors (BCRs) are gathered into microclusters that recruit signaling enzymes. These microclusters then move centripetally and coalesce into the central supr
Externí odkaz:
https://doaj.org/article/495108e2d3d348008c7a1f7e3b66fd17
Autor:
Letitia Falk, May Dang-Lawson, José Luis Vega, Farnaz Pournia, Kate Choi, Caren Jang, Christian C. Naus, Linda Matsuuchi
Publikováno v:
Biology Open, Vol 3, Iss 3, Pp 185-194 (2014)
The gap junction (GJ) protein connexin 43 (Cx43) is both necessary and sufficient for B cell receptor (BCR)-mediated cell spreading. To address how Cx43 mediates this effect, we blocked its function genetically, by expressing mutants of Cx43, and pha
Externí odkaz:
https://doaj.org/article/2778ee5a82ec4efcb0058e444f58b02c
Autor:
Kate Choi, Nancy Reichman
Publikováno v:
Demographic Research, Vol 41, p 8 (2019)
Background: Over the past few decades, the United States has experienced a dramatic rise in the number of multiracial individuals. The health of this population is vastly understudied because most population-based health surveys do not adequately ide
Externí odkaz:
https://doaj.org/article/312c3925190f44649155232c3d0007e5
Autor:
Kate Choi, Erin R. Hamilton
Publikováno v:
Demographic Research, Vol 34, p 40 (2016)
Background: Non-marital fertility differs considerably by race, ethnicity, and nativity. These differences arise largely from racial and ethnic disparities in contraceptive practices. Empirical work has not assessed the relative importance of the var
Externí odkaz:
https://doaj.org/article/3d8db2485fd74ac8898fdee9c24ce290