Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Kate Beebe"'
Autor:
Michael A. Jacobs, Kate Beebe, Rajinder Kaul, Christina Gooch, Grant D. Trobridge, David R. Dickerson, Daniel G. Miller, Tulin Okbinoglu, Hans-Peter Kiem, James Fletcher, Brian C. Beard
Publikováno v:
Molecular Therapy. 15:1356-1365
The potential for leukemia caused by retroviral vector integration has become a significant concern for hematopoietic stem cell gene therapy. We analyzed the distribution of vector integrants in pigtailed macaque and baboon repopulating cells for the
Autor:
Hans-Peter Kiem, David R. Dickerson, Kate Beebe, Brian C. Beard, Christina Gooch, Julia C. Piasecki
Publikováno v:
Blood. 108:3270-3270
In vivo selection strategies that convey a survival advantage to genetically modified cells carrying mutant forms of methylguanine methyltransferase (MGMT-P140K) have the potential to improve autologous and allogeneic stem cell gene therapy and trans
Publikováno v:
Blood. 104:2103-2103
Recent studies in the NOD/SCID model have shown improved engraftment of SCID-repopulating cells and higher levels of engraftment in the secondary transplantation when cells were administered by intramarrow (IM) versus intravenous (IV) injection sugge