Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Kate A. Markey"'
Autor:
Alex E. Wolfe, Kate A. Markey
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Allogenic hematopoietic stem-cell transplantation (allo-HCT) is a curative-intent immunotherapy for high-risk hematological malignancies and immune deficiencies. Allo-HCT carries a high risk of treatment-related mortality (TRM), largely due to infect
Externí odkaz:
https://doaj.org/article/d7e163ab01a34235883c92b0de6eb423
Publikováno v:
Haematologica, Vol 106, Iss 8 (2021)
Microbiota injury occurs in many patients undergoing allogeneic hematopoietic cell transplantation, likely as a consequence of conditioning regimens involving chemo- and radiotherapy, the widespread use of both prophylactic and therapeutic antibiotic
Externí odkaz:
https://doaj.org/article/794b3960907646bc8df05e72e0920dc4
Publikováno v:
Frontiers in Oncology, Vol 10 (2021)
Allogeneic hematopoietic cell transplantation (allo-HCT) is performed as curative-intent therapy for hematologic malignancies and non-malignant hematologic, immunological and metabolic disorders, however, its broader implementation is limited by high
Externí odkaz:
https://doaj.org/article/473b59fdb964473a8da400e883a5a5c5
Autor:
Roni Shouval, Nicholas R. Waters, Antonio L. C. Gomes, Corrado Zuanelli Brambilla, Teng Fei, Sean M. Devlin, Chi L. Nguyen, Kate A. Markey, Anqi Dai, John B. Slingerland, Annelie G. Clurman, Emily Fontana, Luigi A. Amoretti, Roberta J. Wright, Tobias M. Hohl, Ying Taur, Anthony D. Sung, Daniela Weber, Daigo Hashimoto, Takanori Teshima, Nelson J. Chao, Ernst Holler, Michael Scordo, Sergio A. Giralt, Miguel-Angel Perales, Jonathan U. Peled, Marcel R.M. van den Brink
Publikováno v:
Clin Cancer Res
Purpose: The gut microbiota is subject to multiple insults in allogeneic hematopoietic cell transplantation (allo-HCT) recipients. We hypothesized that preparative conditioning regimens contribute to microbiota perturbation in allo-HCT. Experimental
Autor:
Geoffrey R. Hill, Motoko Koyama, Mariapia A. Degli-Esposti, Joseph A. Trapani, Kelli P.A. MacDonald, Christian R. Engwerda, Mark J. Smyth, Glen M. Boyle, Kate A. Markey, Slavica Vuckovic, Antiopi Varelias, Greg Kelly, Vivien R. Sutton, Karshing Chang, Jose Paulo Martins, Christopher E. Andoniou, Rachel D. Kuns, Ping Zhang, Siok-Keen Tey, Jason S. Lee, Kate H. Gartlan, Melody Cheong
Supplementary Figure S1: GVHD survival of lethally-irradiated (day 0, 1000cGy split dose) B6.WT, B6.ASC-/- or B6.NLRP3-/- recipients transplanted with BALB/c BM (5x106) and T cells (5x106). The non-GVHD control group received TCD BM cells (5x106) onl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12c670406bdd6e90ec2d85cea9452ca1
https://doi.org/10.1158/2326-6066.22543108
https://doi.org/10.1158/2326-6066.22543108
Autor:
Geoffrey R. Hill, Motoko Koyama, Mariapia A. Degli-Esposti, Joseph A. Trapani, Kelli P.A. MacDonald, Christian R. Engwerda, Mark J. Smyth, Glen M. Boyle, Kate A. Markey, Slavica Vuckovic, Antiopi Varelias, Greg Kelly, Vivien R. Sutton, Karshing Chang, Jose Paulo Martins, Christopher E. Andoniou, Rachel D. Kuns, Ping Zhang, Siok-Keen Tey, Jason S. Lee, Kate H. Gartlan, Melody Cheong
The adaptor protein ASC (apoptosis-associated speck-like protein containing a CARD) is known to facilitate caspase-1 activation, which is essential for innate host immunity via the formation of the inflammasome complex, a multiprotein structure respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7145b9fd80a40cc0741b069c6d960d1
https://doi.org/10.1158/2326-6066.c.6550138.v1
https://doi.org/10.1158/2326-6066.c.6550138.v1
Autor:
Geoffrey R. Hill, Motoko Koyama, Mariapia A. Degli-Esposti, Joseph A. Trapani, Kelli P.A. MacDonald, Christian R. Engwerda, Mark J. Smyth, Glen M. Boyle, Kate A. Markey, Slavica Vuckovic, Antiopi Varelias, Greg Kelly, Vivien R. Sutton, Karshing Chang, Jose Paulo Martins, Christopher E. Andoniou, Rachel D. Kuns, Ping Zhang, Siok-Keen Tey, Jason S. Lee, Kate H. Gartlan, Melody Cheong
Supplementary Table S1 (related to Fig. 4A): (A) Ingenuity Pathway Analysis derived from the uncorrected dataset displaying top canonical signaling pathways involving differentially regulated genes in recipients as described in Fig.4A. (B) 10 selecte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b81f04af8f07416c8522368ebdbf6e4
https://doi.org/10.1158/2326-6066.22543105.v1
https://doi.org/10.1158/2326-6066.22543105.v1
Autor:
Mark J. Smyth, Nicola Waddell, Geoffrey R. Hill, Kazuyoshi Takeda, Stephen L. Nutt, Stephen Kazakoff, Jasmin Straube, Kate A. Markey, Amelia R. Aguilera, Eva M. Putz, Dipti Vijayan, Deepak Mittal
Supplementary Figure Legends S1-S10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37c4b095d5aa81a627aa12ed8a4471a2
https://doi.org/10.1158/2326-6066.22538504
https://doi.org/10.1158/2326-6066.22538504
Autor:
Mark J. Smyth, Nicola Waddell, Geoffrey R. Hill, Kazuyoshi Takeda, Stephen L. Nutt, Stephen Kazakoff, Jasmin Straube, Kate A. Markey, Amelia R. Aguilera, Eva M. Putz, Dipti Vijayan, Deepak Mittal
Several host factors may affect the spread of cancer to distant organs; however, the intrinsic role of dendritic cells (DC) in controlling metastasis is poorly described. Here, we show in several tumor models that although the growth of primary tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6fc04c531dc0cbd7aafdb247d17a393
https://doi.org/10.1158/2326-6066.c.6548801.v1
https://doi.org/10.1158/2326-6066.c.6548801.v1
Autor:
Marcel R.M. van den Brink, Jonathan U. Peled, Miguel-Angel Perales, Sergio A. Giralt, Michael Scordo, Ernst Holler, Nelson J. Chao, Takanori Teshima, Daigo Hashimoto, Daniela Weber, Anthony D. Sung, Ying Taur, Tobias M. Hohl, Roberta J. Wright, Luigi A. Amoretti, Emily Fontana, Annelie G. Clurman, John B. Slingerland, Anqi Dai, Kate A. Markey, Chi L. Nguyen, Sean M. Devlin, Teng Fei, Corrado Zuanelli Brambilla, Antonio L. C. Gomes, Nicholas R. Waters, Roni Shouval
Purpose:The gut microbiota is subject to multiple insults in allogeneic hematopoietic cell transplantation (allo-HCT) recipients. We hypothesized that preparative conditioning regimens contribute to microbiota perturbation in allo-HCT.Experimental De
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2afc7dae9340a4fc868502fb79e0bc6c
https://doi.org/10.1158/1078-0432.c.6532787.v1
https://doi.org/10.1158/1078-0432.c.6532787.v1