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Autor:
Julie Epikaridisová, Jana Brokešová, Jan Patera, Martin Kuentz, Michaela Slámová, Petr Zámostný, Kateřina Prausová
Publikováno v:
International Journal of Pharmaceutics. 597:120312
Co-milling of a drug with a co-former is an efficient technique to improve the solubility of drugs. Besides the particle size reduction, the co-milling process induces a structural disorder and the creation of amorphous regions. The extent of drug so