Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Kateřina Dvořáčková"'
Autor:
Eliška Mašková, Jan Muselík, Kateřina Dvořáčková, Martina Kejdušová, David Vetchý, Petr Doležel
Publikováno v:
AAPS PharmSciTech. 14:1341-1348
The solubility of weakly basic drugs within passage though GI tract leads to pH-dependent or even incomplete release of these drugs from extended release formulations and consequently to lower drug absorption and bioavailability. The aim of the study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f79966a84b63693fa7c6c94697bd7fe
https://doi.org/10.1208/s12249-013-0019-1
https://doi.org/10.1208/s12249-013-0019-1
Autor:
Ludvík Beneš, Martina Kejdušová, Vratislav Košťál, Kateřina Dvořáčková, Jakub Vysloužil, Petr Doležel
Publikováno v:
Pharmaceutical development and technology. 21(2)
The aim of the study was to prepare PLGA microparticles for prolonged release of mirtazapine by o/w solvent evaporation method and to evaluate effects of PVA concentration and organic solvent choice on microparticles characteristics (encapsulation ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::366b8d05a46c959e1065d6183f9d0922
https://pubmed.ncbi.nlm.nih.gov/25495857
https://pubmed.ncbi.nlm.nih.gov/25495857
Autor:
Aleš, Franc, Kateřina, Dvořáčková, Jan, Muselík, Martina, Zvaková, Vladimíra, Slováková, David, Vetchý, Dana, Sabadková, David, Neumann, Roman, Goněc
Publikováno v:
Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti. 63(5)
Hypoglycemic episodes are a frequent and serious complication in both types of diabetes mellitus. The risk of hypoglycemic conditions can be managed by a coated pellet dosage form, which can release glucose in a delayed regime to achieve the maximum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2b65c12183cefc5d8b8616ce569865c2
https://pubmed.ncbi.nlm.nih.gov/25354740
https://pubmed.ncbi.nlm.nih.gov/25354740
Publikováno v:
Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti. 63(3)
The aim of this experimental study was to optimize a preparation of microspheres from high viscosity chitosan by external ion gelation and to evaluate selected aspects of their preparation. For drug-free microparticles, the concentration of chitosan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a1011d1f73c5d666680a8e40a3fa2756
https://pubmed.ncbi.nlm.nih.gov/25115666
https://pubmed.ncbi.nlm.nih.gov/25115666
Autor:
Petr Doležel, David Vetchý, Josef Mašek, Jakub Vysloužil, Kateřina Dvořáčková, Eliška Mašková, Róbert Lukáč, Martina Kejdušová, Vratislav Košťál
Publikováno v:
Acta Pharmaceutica, Vol 64, Iss 4, Pp 403-417 (2014)
The main objective of this study was to evaluate the influence of the formulation and process parameters on PLGA microparticles containing a practically insoluble model drug (ibuprofen) prepared by the o/w solvent evaporation method. Multivariate dat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba190a7e92b7e0f8b5deae350bf41f00
https://pubmed.ncbi.nlm.nih.gov/25531782
https://pubmed.ncbi.nlm.nih.gov/25531782
Publikováno v:
Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti. 63(2)
This study aimed to prepare high molecular weight chitosan blank and drug-loaded microparticles using 5-aminosalicylic acid (5-ASA) as the model active substance by an external ionic gelation. Formulation and process variables included the chitosan c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ce7df97ce6b1c240d5baf9d45caabdbe
https://pubmed.ncbi.nlm.nih.gov/24870552
https://pubmed.ncbi.nlm.nih.gov/24870552
Autor:
Jurga Bernatoniene, Jan Gajdziok, Jan Muselík, Rasa Kaledaite, Rimantas Pečiūra, Kateřina Dvořáčková, Ruta Masteiková
Publikováno v:
Pharmaceutical development and technology. 20(7)
The objective of this study was to prepare pellets of thyme (Thymus vulgaris L.), stinging nettle (Urtica dioica L.) and sage (Salvia officinalis L.) dry extracts by extrusion-spheronization technique to improve technological properties and investiga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06faf3e3127d3432af91fb116d0a23e7
https://pubmed.ncbi.nlm.nih.gov/24841190
https://pubmed.ncbi.nlm.nih.gov/24841190
Publikováno v:
Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti. 62(6)
Three cationic acrylic polymers, i. e. Eudragit® RL, Eudragit® RS and Eudragit® E 100, were evaluated for the purpose of microparticles preparation by the solvent evaporation method. The practically insoluble drug mirtazapine and the freely solubl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0e0cb5efd2b087e2752f46c4e1ee9a15
https://pubmed.ncbi.nlm.nih.gov/24393112
https://pubmed.ncbi.nlm.nih.gov/24393112
Publikováno v:
Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti. 62(6)
Orally administered drugs are passed through the gastrointestinal tract (GIT), which influences their next metabolism in the body. In the case of systemic administration, the drug is released from the dosage form, is dissolved and eventually absorbed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f4a31ed9e0f2b3930b848db0b8f43512
https://pubmed.ncbi.nlm.nih.gov/24393111
https://pubmed.ncbi.nlm.nih.gov/24393111
Autor:
Kateřina Dvořáčková, Karel Hauptman, Hana Landová, Jan Gajdziok, David Vetchý, Jan Muselík, Petr Doležel, Zdeněk Knotek, Vladimir Jekl
Publikováno v:
BioMed Research International, Vol 2014 (2014)
BioMed Research International
BioMed Research International
Oral mucosa is an attractive region for the local and systemic application of many drugs. Oral mucoadhesive films are preferred for their prolonged time of residence, the improved bioavailability of the drug they contain, their painless application,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edaac93eef65e96f4e06c3e773edd987
https://doaj.org/article/55f052cbe9b8484b8b152c83ecf377c0
https://doaj.org/article/55f052cbe9b8484b8b152c83ecf377c0