Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Kateřina, Levová"'
Autor:
Marta Kalousová, Sylvie Dusilová-Sulková, Aleš A. Kuběna, Oskar Zakiyanov, Kateřina Levová, Markéta Bocková, Erika Gedeonová, Xue Chadtová Song, Maria Laura Ermini, Tomáš Špringer, Jiří Homola, Vladimír Tesař, Tomáš Zima
Publikováno v:
Kidney & Blood Pressure Research, Vol 42, Iss 3, Pp 509-518 (2017)
Background: Pregnancy-associated plasma protein A (PAPP-A) is associated with adverse outcome of long-term hemodialysis patients (HD). The aim of the study was to test whether its homolog pregnancy-associated plasma protein A2 (PAPP-A2) can be detect
Externí odkaz:
https://doaj.org/article/4ea41681e28049b6a35b0d887e438131
Autor:
Ranjani Ganapathy S., Kateřina Levová, Lenka Kotačková, Jiří Trnka, David Zogala, Jan Rusz, Tomáš Zima, David Devos, Karel Šonka, Evžen Růžička, Marta Kalousová, Petr Dušek
Publikováno v:
Movement Disorders. 37:983-992
Sialic acid-protein interactions are involved in regulating central nervous system immunity; therefore, derangements in sialylation could be involved in neurodegeneration.We evaluate the differences in serum transferrin sialylation in prodromal and e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52b82e24694dfd8fcba499d4a30315c8
https://doi.org/10.1002/mds.28942
https://doi.org/10.1002/mds.28942
Autor:
Tomáš Hanuš, Roman Sobotka, Kateřina Levová, Tomáš Zima, Marta Kalousová, L Vavrova, Michael Pešl, Viktor Soukup, Otakar Čapoun
Publikováno v:
Neoplasma. 66(6)
Aim of the study is to define the diagnostic accuracy of selected urinary protein biomarkers in the non-invasive detection of primary and recurrent urothelial carcinoma of the urinary bladder. The urinary levels of calprotectin, CD147, APOA4 and prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ce9f3bf67ea2f2215edc0dcec0be6c0
https://pubmed.ncbi.nlm.nih.gov/31607136
https://pubmed.ncbi.nlm.nih.gov/31607136
Autor:
Tomáš Zima, Marta Kalousová, Kateřina Levová, Erika Gedeonová, Xue Chadtová Song, Jiří Homola, Markéta Bocková
Publikováno v:
Analytical and Bioanalytical Chemistry. 408:7265-7269
Pregnancy associated plasma protein A2 (PAPP-A2) is a metalloproteinase that plays multiple roles in fetal development and post-natal growth. Here we present a novel surface plasmon resonance (SPR) biosensor for the rapid and quantitative detection o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ad51bc86b001294cf6a6a22e28d0c8f
https://doi.org/10.1007/s00216-016-9664-z
https://doi.org/10.1007/s00216-016-9664-z
Autor:
Volker M. Arlt, Heinz H. Schmeiser, Kateřina Levová, Marie Stiborová, František Bárta, Petr Hodek, Václav Martínek
Publikováno v:
International Journal of Molecular Sciences; Volume 16; Issue 11; Pages: 27561-27575
Stiborová, M, Bárta, F, Levová, K, Hodek, P, Schmeiser, H H, Arlt, V M & Martínek, V 2015, ' A mechanism of O-demethylation of aristolochic acid I by cytochromes P450 and their contributions to this reaction in human and rat livers : Experimental and theoretical approaches ', International Journal of Molecular Sciences, vol. 16, no. 11, pp. 27561-27575 . https://doi.org/10.3390/ijms161126047
International Journal of Molecular Sciences, Vol 16, Iss 11, Pp 27561-27575 (2015)
International Journal of Molecular Sciences
Stiborová, M, Bárta, F, Levová, K, Hodek, P, Schmeiser, H H, Arlt, V M & Martínek, V 2015, ' A mechanism of O-demethylation of aristolochic acid I by cytochromes P450 and their contributions to this reaction in human and rat livers : Experimental and theoretical approaches ', International Journal of Molecular Sciences, vol. 16, no. 11, pp. 27561-27575 . https://doi.org/10.3390/ijms161126047
International Journal of Molecular Sciences, Vol 16, Iss 11, Pp 27561-27575 (2015)
International Journal of Molecular Sciences
Aristolochic acid I (AAI) is a plant alkaloid causing aristolochic acid nephropathy, Balkan endemic nephropathy and their associated urothelial malignancies. AAI is detoxified by cytochrome P450 (CYP)-mediated O-demethylation to 8-hydroxyaristolochic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a533317c104ec1d2c59504d0d51095ef
https://doi.org/10.3390/ijms161126047
https://doi.org/10.3390/ijms161126047
Autor:
Marie Stiborová, Volker M. Arlt, Kateřina Levová, Heinz H. Schmeiser, Miroslav Sulc, František Bárta, Eva Frei
Publikováno v:
Stiborová, M, Levová, K, Bárta, F, Sulc, M, Frei, E, Arlt, V M & Schmeiser, H H 2014, ' The influence of dicoumarol on the bioactivation of the carcinogen aristolochic acid I in rats ', Mutagenesis, vol. 29, no. 3, pp. 189-200 . https://doi.org/10.1093/mutage/geu004
UNLABELLED Aristolochic acid I (AAI) is the major toxic component of the plant extract AA, which leads to the development of nephropathy and urothelial cancer in human. Individual susceptibility to AAI-induced disease might reflect variability in enz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::190680c65fe06871e8306a8259ebd0cf
https://doi.org/10.1093/mutage/geu004
https://doi.org/10.1093/mutage/geu004
Publikováno v:
Studia sportiva. 6:107-111
The objective of paper is to compare the exercise intensity during playing the active video game PlayDance on dancing pads with playing on crosses marked on the ground. All respondents were student of university, 21-26 years old, with minimum previou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e9ed7c8be35ad84711a981536ea9bc1
https://doi.org/10.5817/sts2012-2-13
https://doi.org/10.5817/sts2012-2-13
Autor:
Eva Frei, David H. Phillips, Daniel W. Nebert, František Bárta, Kateřina Levová, Volker M. Arlt, Zhanquan Shi, Heinz H. Schmeiser, James D. Evans, Marie Stiborová
Publikováno v:
Chemical Research in Toxicology. 24:1710-1719
Exposure to aristolochic acid I (AAI) is associated with aristolochic acid nephropathy, Balkan endemic nephropathy, and urothelial cancer. Individual differences in xenobiotic-metabolizing enzyme activities are likely to be a reason for interindividu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa35ba827ceb0f87957513fa0decb720
https://doi.org/10.1021/tx200259y
https://doi.org/10.1021/tx200259y
Autor:
David H. Phillips, Marie Stiborová, Věra Kotrbová, Heinz H. Schmeiser, J. Mareš, Colin J. Henderson, C. Roland Wolf, Michaela Moserová, Eva Frei, Kateřina Levová, Volker M. Arlt, Miroslav Šulc
Publikováno v:
Levova, K, Moserova, M, Kotrbova, V, Sulc, M, Henderson, C J, Wolf, C R, Phillips, D H, Frei, E, Schmeiser, H H, Mares, J, Arlt, V M & Stiborova, M 2011, ' Role of Cytochromes P450 1A1/2 in detoxication and activation of carcinogenic aristolochic acid I : studies with the Hepatic NADPH:Cytochrome P450 Reductase Null (HRN) mouse model ', Toxicological Sciences, vol. 121, no. 1, pp. 43-56 . https://doi.org/10.1093/toxsci/kfr050
Aristolochic acid (AA) causes aristolochic acid nephropathy, Balkan endemic nephropathy, and their urothelial malignancies. To identify enzymes involved in the metabolism of aristolochic acid I (AAI), the major toxic component of AA we used HRN (hepa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4a0d093b542d601502797a53bb6a159
https://doi.org/10.1093/toxsci/kfr050
https://doi.org/10.1093/toxsci/kfr050
Autor:
Helena, Dračínská, František, Bárta, Kateřina, Levová, Alena, Hudecová, Michaela, Moserová, Heinz H, Schmeiser, Klaus, Kopka, Eva, Frei, Volker M, Arlt, Marie, Stiborová
Publikováno v:
Toxicology
Highlights • Oxidation and reduction of aristolochic acid I (AAI) dictate its (geno)toxicity in vivo. • Cytochrome P450 (CYP) 1A1 and 1A2 are induced in rats treated with Sudan I and AAI. • Induced CYP1A enzyme activity resulted in decreased AA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e265a367b0fb046d1d0c438d776989f5
https://pubmed.ncbi.nlm.nih.gov/26845733
https://pubmed.ncbi.nlm.nih.gov/26845733