Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Kateřina, Kubáčková"'
Autor:
Tereza Kunická, Radka Václavíková, Viktor Hlaváč, David Vrána, Václav Pecha, Karel Rauš, Markéta Trnková, Kateřina Kubáčková, Miloslav Ambruš, Ludmila Vodičková, Pavel Vodička, Pavel Souček
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101740 (2014)
ATP-Binding Cassette (ABC) transporters may cause treatment failure by transporting of anticancer drugs outside of the tumor cells. Multidrug resistance-associated protein 1 coded by the ABCC1 gene has recently been suggested as a potential prognosti
Externí odkaz:
https://doaj.org/article/c590e3ce1b594a8fa828886f85ceb0e3
Autor:
Karel Rauš, Roman Kodet, David Vrána, Radka Vaclavikova, Marie Bendová, Pavel Soucek, Kateřina Kubáčková, Veronika Brynychova, Jiří Gatěk, Marcela Mrhalova
Publikováno v:
Klinicka onkologie. 29:445-453
Background Caspase-8 and caspase-9 (encoded by CASP8 and CASP9) are executive caspases of programmed cell death (apoptosis). Dysregulation of apoptosis plays an important role in cancer development, progression, and resistance to anticancer therapy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::410783372ed99c2c0755061eeace2d30
https://doi.org/10.14735/amko2016445
https://doi.org/10.14735/amko2016445
Autor:
Jozef Mardiak, R. A. Popescu, Tanja Cufer, Galia Kurteva, Kateřina Kubáčková, Semir Beslija, Vladimir Todorovic, Robert Pirker, Snezhana Smichkoska, György Bodoky, Eduard Vrdoljak, Žarko Bajić, Alexandru Eniu, Branimir I. Sikic, Zorica Tomasevic, Agim Sallaku, Jacek Jassem
Publikováno v:
The Oncologist. 21:1183-1190
The incidence of many cancers is higher in Western European (WE) countries, but mortality is frequently higher in Central and Eastern European (CEE) countries. A panel of oncology leaders from CEE countries participating in the South Eastern European
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee4109f9cecb9b959378f02cd3db4ec7
https://doi.org/10.1634/theoncologist.2016-0137
https://doi.org/10.1634/theoncologist.2016-0137
Autor:
Petra Pokorná, Kateřina Kubáčková, Rostislav Vyzula, Zdeněk Linke, Tomáš Pikus, Jana Prausová, Zbyněk Bortlíček
Publikováno v:
Future Oncology. 11:225-232
ABSTRACT Aim: This retrospective analysis investigated the effectiveness of combination therapy with bevacizumab and chemotherapy in the first-line treatment of patients with KRAS wild-type metastatic colorectal cancer. Patients & methods: Patients w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6b7757e165dadfefdaabdd2375b2dbf
https://doi.org/10.2217/fon.14.240
https://doi.org/10.2217/fon.14.240
Autor:
Jan Pirk, T. Gazdic, Josef Kautzner, Kateřina Kamarádová, Kateřina Kubáčková, Jan Vydra, Renata Virtová, Radka Kockova, Otakar Bělohlávek, Dana Kautznerová
Publikováno v:
Cor et Vasa. 56(3):e274-e278
Liposarcomas are malignant tumors of the soft tissue. Myxoid liposarcoma is the second most common subtype of these tumors in adults. It accounts for approximately 20% of all malignant soft tissue tumors [1] , [2] . Peak of its incidence occurs betwe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65f2d6b194c8a25c79d75f199aa4a010
Autor:
Pavel Soucek, Tomáš Pikus, Jan Kovář, Viktor Hlavac, Veronika Brynychova, Marcela Mrhalova, Radka Vaclavikova, Roman Kodet, Kateřina Kubáčková, Marie Ehrlichová, Marketa Trnkova, Martin Wald, Vaclav Pecha
Publikováno v:
Future Oncology. 9:427-438
Aim: A role of caspase-2 in chemotherapy-induced apoptosis has been suggested. Our study aimed to evaluate the prognostic and predictive importance of caspase-2 isoforms in breast cancer patients. Materials & methods: Caspase-2L and -2S transcript le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d5f14504039d50ef4cb4913d39dcb00
https://doi.org/10.2217/fon.12.200
https://doi.org/10.2217/fon.12.200
Autor:
Kateřina Kubáčková
Publikováno v:
Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti. 28
In recent years, thanks to new advances in tumor immunology, immunotherapy became a part of intensive research as a novel strategy in cancer treatment. Sipuleucel T is the first and only medicinal product approved by the regulatory agencies in the US
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bb0468c76ef888c867931400396bcb4
https://pubmed.ncbi.nlm.nih.gov/26647892
https://pubmed.ncbi.nlm.nih.gov/26647892
Autor:
Iveta, Mrízová, Michaela, Moserová, Jan, Milichovský, Miroslav, Šulc, René, Kizek, Kateřina, Kubáčková, Volker M, Arlt, Marie, Stiborová
Publikováno v:
Monatshefte Fur Chemie
Cytochrome P450 (CYP) 2S1 is “orphan” CYP that is overexpressed in several epithelial tissues and many human tumors. The pure enzyme is required for better understanding of its biological functions. Therefore, human CYP2S1 was considered to be pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::129b4fcd01f6a9c0c4a6ff94b4b42bc0
https://pubmed.ncbi.nlm.nih.gov/27110039
https://pubmed.ncbi.nlm.nih.gov/27110039
Autor:
Marie, Stiborová, Michaela, Moserová, Iveta, Mrízová, Helena, Dračínská, Václav, Martínek, Radek, Indra, Eva, Frei, Vojtěch, Adam, René, Kizek, Heinz H, Schmeiser, Kateřina, Kubáčková, Volker M, Arlt
Publikováno v:
Monatshefte Fur Chemie
The microsomal protein cytochrome b 5, which is located in the membrane of the endoplasmic reticulum, has been shown to modulate many reactions catalyzed by cytochrome P450 (CYP) enzymes. We investigated the influence of exposure to the anticancer dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1951ebbd9af6a8b2a26cc4c870f6a07d
https://pubmed.ncbi.nlm.nih.gov/27110040
https://pubmed.ncbi.nlm.nih.gov/27110040
Autor:
Marketa Trnkova, Pavel Soucek, Marie Ehrlichová, Jiří Gatěk, Radka Vaclavikova, Veronika Brynychova, Roman Kodet, David Vrána, Kateřina Kubáčková, Viktor Hlavac, Vaclav Pecha, Petr Vážan, Marcela Mrhalova
Publikováno v:
Medicine
Medicine (United States)
Medicine (United States)
Metabolism of anticancer drugs affects their antitumor effects. This study has investigated the associations of gene expression of enzymes metabolizing anticancer drugs with therapy response and survival of breast carcinoma patients.Gene expression o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18b303d18e2fef4243052999bd3a92f3
http://europepmc.org/articles/PMC4603110
http://europepmc.org/articles/PMC4603110