Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Kateřina, Bogdanová"'
Delivery of N-heterocyclic drugs, acids, phenols, and thiols via Tailor−made Self−immolative linkers
Autor:
Vahid Barati, Anna Hruzíková, Eliška Procházková, Martin Zavřel, Jaroslav Kozák, Jana Trylčová, Dominik Rejman, Jan Weber, Kateřina Bogdanová, Milan Kolář, Ondřej Baszczyňski
Publikováno v:
European Journal of Medicinal Chemistry Reports, Vol 12, Iss , Pp 100216- (2024)
Heterocyclic drugs display diverse pharmacological activities and metabolic stability. However, their poor solubility and pharmacokinetic properties often compromise bioavailability and clinical outcomes. Nevertheless, the prodrug approach provides a
Externí odkaz:
https://doaj.org/article/02da55a35360455dbc11c50a0c3d790f
Autor:
Klára Látrová, Noemi Havlová, Renata Večeřová, Dominik Pinkas, Kateřina Bogdanová, Milan Kolář, Radovan Fišer, Ivo Konopásek, Duy Dinh Do Pham, Dominik Rejman, Gabriela Mikušová
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract Lipophosphonoxins (LPPOs) are small modular synthetic antibacterial compounds that target the cytoplasmic membrane. First-generation LPPOs (LPPO I) exhibit an antimicrobial activity against Gram-positive bacteria; however they do not exhibit
Externí odkaz:
https://doaj.org/article/2c8af9111366446e9e22f3b263b30b4d
Autor:
Eva Zborníková, Jiří Gallo, Renata Večeřová, Kateřina Bogdanová, Milan Kolář, Dragana Vítovská, Duy Dinh Do Pham, Ondřej Pačes, Viktor Mojr, Hana Šanderová, Jitka Ulrichová, Adéla Galandáková, Drahomír Čadek, Zdeněk Hrdlička, Libor Krásný, Dominik Rejman
Publikováno v:
ACS Omega, Vol 5, Iss 7, Pp 3165-3171 (2020)
Externí odkaz:
https://doaj.org/article/e64a31f187e142679597e8e7a2d6590d
Autor:
Matej Rosa, Yuliya Morozova, Roman Moštěk, Pavel Holík, Lucia Somolová, Barbora Novotná, Soňa Zábojníková, Kateřina Bogdanová, Kateřina Langová, Iva Voborná, Lenka Pospíšilová, Josef Paul Kovařík
Publikováno v:
Life, Vol 12, Iss 2, p 158 (2022)
(1) Background: Microorganisms originating from the microflora of the oral cavity are the main cause of the inflammatory diseases of the dental pulp and periapical periodontium, as well as the failure of endodontic treatment. The subsequent root cana
Externí odkaz:
https://doaj.org/article/64ad8be5d91f484aaa46179870636d49
Autor:
Yuliya Morozova, Iva Voborná, Radovan Žižka, Kateřina Bogdanová, Renata Večeřová, Dominik Rejman, Milan Kolář, Duy Dinh Do Pham, Pavel Holík, Roman Moštěk, Matej Rosa, Lenka Pospíšilová
Publikováno v:
Life, Vol 12, Iss 1, p 129 (2022)
(1) Background: The root canal system has complex anatomical and histological features that make it impossible to completely remove all bacteria by mechanical means only; they must be supplemented with disinfectant irrigation. Current disinfectants a
Externí odkaz:
https://doaj.org/article/2058d3cffc85477798569286090774ab
Autor:
Kateřina Bogdanová, Lenka Doubravská, Iva Vágnerová, Kristýna Hricová, Vendula Pudová, Magdaléna Röderová, Jan Papajk, Radovan Uvízl, Kateřina Langová, Milan Kolář
Publikováno v:
Life, Vol 11, Iss 11, p 1127 (2021)
Broad-spectrum antibiotics administered to patients with severe COVID-19 pneumonia pose a risk of infection caused by Clostridioides difficile. This risk is reduced mainly by strict hygiene measures and early de-escalation of antibiotic therapy. Rece
Externí odkaz:
https://doaj.org/article/d70a4399caf749338b4fdd4b797431ff
Autor:
Duy Dinh Do Pham, Viktor Mojr, Michaela Helusová, Gabriela Mikušová, Radek Pohl, Eva Dávidová, Hana Šanderová, Dragana Vítovská, Kateřina Bogdanová, Renata Večeřová, Miroslava Htoutou Sedláková, Radovan Fišer, Petra Sudzinová, Jiří Pospíšil, Oldřich Benada, Tomáš Křížek, Adéla Galandáková, Milan Kolář, Libor Krásný, Dominik Rejman
Publikováno v:
Journal of Medicinal Chemistry. 65:10045-10078
The alarming rise of bacterial antibiotic resistance requires the development of new compounds. Such compounds, lipophosphonoxins (LPPOs), were previously reported to be active against numerous bacterial species, but serum albumins abolished their ac
Autor:
Zdeněk Hrdlička, Eva Zborníková, Milan Kolář, Ondřej Pačes, Dominik Rejman, Dragana Vítovská, Libor Krásný, Jitka Ulrichová, Duy Dinh Do Pham, Drahomír Čadek, Hana Šanderová, Viktor Mojr, Kateřina Bogdanová, J. Gallo, Adéla Galandáková, Renata Večeřová
Publikováno v:
ACS Omega
ACS Omega, Vol 5, Iss 7, Pp 3165-3171 (2020)
ACS Omega, Vol 5, Iss 7, Pp 3165-3171 (2020)
Successful surgeries involving orthopedic implants depend on the avoidance of biofilm development on the implant surface during the early postoperative period. Here, we investigate the potential of novel antibacterial compounds-second-generation lipo
Autor:
Matej, Rosa, Yuliya, Morozova, Roman, Moštěk, Pavel, Holík, Lucia, Somolová, Barbora, Novotná, Soňa, Zábojníková, Kateřina, Bogdanová, Kateřina, Langová, Iva, Voborná, Lenka, Pospíšilová, Josef Paul, Kovařík
Publikováno v:
Life (Basel, Switzerland). 12(2)
(1) Background: Microorganisms originating from the microflora of the oral cavity are the main cause of the inflammatory diseases of the dental pulp and periapical periodontium, as well as the failure of endodontic treatment. The subsequent root cana
Autor:
Yuliya, Morozova, Iva, Voborná, Radovan, Žižka, Kateřina, Bogdanová, Renata, Večeřová, Dominik, Rejman, Milan, Kolář, Duy Dinh, Do Pham, Pavel, Holík, Roman, Moštěk, Matej, Rosa, Lenka, Pospíšilová
Publikováno v:
Life
(1) Background: The root canal system has complex anatomical and histological features that make it impossible to completely remove all bacteria by mechanical means only; they must be supplemented with disinfectant irrigation. Current disinfectants a