Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Kate, Megquier"'
Autor:
Lucas Rodrigues, Joshua Watson, Yuan Feng, Benjamin Lewis, Garrett Harvey, Gerald Post, Kate Megquier, Michelle E. White, Lindsay Lambert, Aubrey Miller, Christina Lopes, Shaying Zhao
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Naturally occurring canine cancers have remarkable similarities to their human counterparts. To better understand these similarities, we investigated 671 client-owned dogs from 96 breeds with 23 common tumor types, including those whose muta
Externí odkaz:
https://doaj.org/article/c998cd0c12a6457ab3eb8c99d28fbd9f
Autor:
Kate Megquier, Jason Turner-Maier, Kathleen Morrill, Xue Li, Jeremy Johnson, Elinor K Karlsson, Cheryl A London, Heather L Gardner
Publikováno v:
PLoS ONE, Vol 17, Iss 9, p e0274383 (2022)
The characterization of immortalized canine osteosarcoma (OS) cell lines used for research has historically been based on phenotypic features such as cellular morphology and expression of bone specific markers. With the increasing use of these cell l
Externí odkaz:
https://doaj.org/article/141e55c5532a44ba85cdda09c7b40708
Autor:
Kerstin Lindblad-Toh, Ingegerd Elvers, Jaime F. Modiano, Matthew Breen, Elinor K. Karlsson, Rachael Thomas, Corrie Painter, Jessica Alfoldi, Noriko Tonomura, Luke Borst, Ashley J. Schulte, Milcah C. Scott, Mitzi Lewellen, Michele Koltookian, Jeremy Johnson, Sharadha Sakthikumar, Chao Wang, Aaron L. Sarver, Jong-Hyuk Kim, Ross Swofford, Jason Turner-Maier, Kate Megquier
Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c32caa37ff058953d7c8963ec184eda
https://doi.org/10.1158/1541-7786.22515477.v1
https://doi.org/10.1158/1541-7786.22515477.v1
Autor:
Kerstin Lindblad-Toh, Ingegerd Elvers, Jaime F. Modiano, Matthew Breen, Elinor K. Karlsson, Rachael Thomas, Corrie Painter, Jessica Alfoldi, Noriko Tonomura, Luke Borst, Ashley J. Schulte, Milcah C. Scott, Mitzi Lewellen, Michele Koltookian, Jeremy Johnson, Sharadha Sakthikumar, Chao Wang, Aaron L. Sarver, Jong-Hyuk Kim, Ross Swofford, Jason Turner-Maier, Kate Megquier
Table S1. Canine cohort metadata Table S2. Canine library preparation, amplification, and complexity Table S3. COSMIC Cancer Gene Census genes Table S4. Summary of canine RNA-seq data Table S5. RNA-seq validation Table S6. RNA-seq survey Table S7. En
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e8e0170833c99fa01b267c8b24042e9
https://doi.org/10.1158/1541-7786.22515474.v1
https://doi.org/10.1158/1541-7786.22515474.v1
Autor:
Kerstin Lindblad-Toh, Ingegerd Elvers, Jaime F. Modiano, Matthew Breen, Elinor K. Karlsson, Rachael Thomas, Corrie Painter, Jessica Alfoldi, Noriko Tonomura, Luke Borst, Ashley J. Schulte, Milcah C. Scott, Mitzi Lewellen, Michele Koltookian, Jeremy Johnson, Sharadha Sakthikumar, Chao Wang, Aaron L. Sarver, Jong-Hyuk Kim, Ross Swofford, Jason Turner-Maier, Kate Megquier
Supplemental Table 7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03fdd0526168cadefc71269476da7449
https://doi.org/10.1158/1541-7786.22515480.v1
https://doi.org/10.1158/1541-7786.22515480.v1
Autor:
Jaime F. Modiano, Kerstin Lindblad-Toh, Matthew Breen, Elinor K. Karlsson, Jason Turner-Maier, Ross Swofford, Ingegerd Elvers, Colleen L. Forster, LeAnn Oseth, Paari Murugan, Michael A. Linden, Ashley J. Schulte, Nuojin Cheng, Yoon Tae Kim, Jung Min Song, Aaron L. Sarver, Rachael Thomas, Kate Megquier, Jong Hyuk Kim
Table S1. Demographic and pathological features of human patients with angiosarcoma Table S2. Demographic and pathological features of dogs with HSA Table S3. Primary antibodies for immunohistochemical evaluation Table S4. Gene ontology and biologica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35ab93e5f9c6d85ffd7e05a785309457
https://doi.org/10.1158/1541-7786.22526675
https://doi.org/10.1158/1541-7786.22526675
Autor:
Kerstin Lindblad-Toh, Ingegerd Elvers, Jaime F. Modiano, Matthew Breen, Elinor K. Karlsson, Rachael Thomas, Corrie Painter, Jessica Alfoldi, Noriko Tonomura, Luke Borst, Ashley J. Schulte, Milcah C. Scott, Mitzi Lewellen, Michele Koltookian, Jeremy Johnson, Sharadha Sakthikumar, Chao Wang, Aaron L. Sarver, Jong-Hyuk Kim, Ross Swofford, Jason Turner-Maier, Kate Megquier
Angiosarcoma is a highly aggressive cancer of blood vessel–forming cells with few effective treatment options and high patient mortality. It is both rare and heterogenous, making large, well-powered genomic studies nearly impossible. Dogs commonly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0229b663319dc1dc3ceeea0bd2c1725
https://doi.org/10.1158/1541-7786.c.6541095
https://doi.org/10.1158/1541-7786.c.6541095
Autor:
Jaime F. Modiano, Kerstin Lindblad-Toh, Matthew Breen, Elinor K. Karlsson, Jason Turner-Maier, Ross Swofford, Ingegerd Elvers, Colleen L. Forster, LeAnn Oseth, Paari Murugan, Michael A. Linden, Ashley J. Schulte, Nuojin Cheng, Yoon Tae Kim, Jung Min Song, Aaron L. Sarver, Rachael Thomas, Kate Megquier, Jong Hyuk Kim
Sporadic angiosarcomas are aggressive vascular sarcomas whose rarity and genomic complexity present significant obstacles in deciphering the pathogenic significance of individual genetic alterations. Numerous fusion genes have been identified across
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6edc6274e8dfd5447cb0fc32d0ba578
https://doi.org/10.1158/1541-7786.c.6545168.v1
https://doi.org/10.1158/1541-7786.c.6545168.v1
Autor:
Jaime F. Modiano, Kerstin Lindblad-Toh, Matthew Breen, Elinor K. Karlsson, Jason Turner-Maier, Ross Swofford, Ingegerd Elvers, Colleen L. Forster, LeAnn Oseth, Paari Murugan, Michael A. Linden, Ashley J. Schulte, Nuojin Cheng, Yoon Tae Kim, Jung Min Song, Aaron L. Sarver, Rachael Thomas, Kate Megquier, Jong Hyuk Kim
S1. Representative putative inter-chromosomal fusion transcripts in human AS and canine HSA. SCLT1-NIPBL fusion in human angiosarcoma. S2. Fusion genes and their association with tumor content and sequencing depth in canine HSA tissues. S3. A, Primer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61e7422334c171c938bb4047db66745d
https://doi.org/10.1158/1541-7786.22526678.v1
https://doi.org/10.1158/1541-7786.22526678.v1
Autor:
Michelle E. White, Marta Castelhano, Stephen Schwartz, Silvan Urfer, Kate Megquier, Virginia Fajt
Publikováno v:
Vet Comp Oncol
Although cancer is widely regarded as a major contributor to canine morbidity and mortality, its frequency in companion dogs has only infrequently been characterised. We analysed cross-sectional data from the baseline survey of owners of 27 541 livin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::decff4ae14d233b5632aaebae2a2cc90
https://doi.org/10.1111/vco.12839
https://doi.org/10.1111/vco.12839