Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Kate, Huang"'
Autor:
Rui Zhao, Jiacheng Li, Bo Chen, Jungang Zhao, Leyin Hu, Kate Huang, Qiwen Chen, Jiangqiao Yao, Ganglian Lin, Lishimeng Bao, Mengmeng Lu, Yi Wang, Gang Chen, Fang Wu
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Backgrounds and aimsImmunotherapies have formed an entirely new treatment paradigm for hepatocellular carcinoma (HCC). Tertiary lymphoid structure (TLS) has been associated with good response to immunotherapy in most solid tumors. Nonetheless, the ro
Externí odkaz:
https://doaj.org/article/6efe1d583708410398160feafdc6a64e
Autor:
Yafei Zhang, Bingqian Yang, Chengwei Tu, Yifan Ping, Shuhong Chen, Tong Wu, Zheyu Zhao, Yixin Mao, Zhan Yang, Zelin Cao, Jianmin Li, Kate Huang, Xi Ding, Gang Wu, Peng Zou, Zhennan Deng, Xiaoyu Sun
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-17 (2023)
Abstract Background Oral squamous cell carcinoma (OSCC) is one of the most prevalent and fatal oral cancers. Mitochondria-targeting therapies represent promising strategies against various cancers, but their applications in treating OSCC are limited.
Externí odkaz:
https://doaj.org/article/93397a6b0bf942b6ac4c2b59107da2c4
Autor:
Jiali Fu, Jingjing Pan, Xiang Yang, Yan Zhang, Fanggui Shao, Jie Chen, Kate Huang, Yumin Wang
Publikováno v:
Cancer Cell International, Vol 21, Iss 1, Pp 1-17 (2021)
Abstract Aim This study aimed to explore the mechanism of LncRNA urothelial carcinoma-associated 1 (UCA1) promoting cisplatin resistance in lung adenocarcinoma (LUAD). Method The UCA1 expression level in LUAD cell lines was detected by reverse transc
Externí odkaz:
https://doaj.org/article/7293d7cc201e4d4086add170c56673eb
Autor:
Yongzhang Liu, Linhua Lan, Yujie Li, Jing Lu, Lipeng He, Yao Deng, Mingming Fei, Jun-Wan Lu, Fugen Shangguan, Ju-Ping Lu, Jiaxin Wang, Liang Wu, Kate Huang, Bin Lu
Publikováno v:
Redox Biology, Vol 54, Iss , Pp 102366- (2022)
Despite the evidences of elevated expression of Mer tyrosine kinase (MerTK) in multiple human cancers, mechanisms underlying the oncogenic roles of MerTK in hepatocellular carcinoma (HCC) remains undefined. We explored the functional effects of MerTK
Externí odkaz:
https://doaj.org/article/c1acce9994474d378a9ac6ae6e6cd5f3
Autor:
Kate Huang, Changjun Rao, Qun Li, Jianglong Lu, Zhangzhang Zhu, Chengde Wang, Ming Tu, Chaodong Shen, Shuizhi Zheng, Xiaofang Chen, Fangfang Lv
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
BackgroundGlioblastoma multiforme (GBM) is a common malignant brain tumor with high mortality. It is urgently necessary to develop a new treatment because traditional approaches have plateaued.PurposeHere, we identified an immune-related gene (IRG)-b
Externí odkaz:
https://doaj.org/article/4aff39075c2e407681edbf3f54d59e59
Autor:
Ahmed, Rashik, Mingyang Liang, Hudson, Rhea P., Rangadurai, Atul K., Shuya Kate Huang, Forman-Kay, Julie D., Kay, Lewis E.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 8/27/2024, Vol. 121 Issue 35, p1-12, 28p
Autor:
Shuya Kate Huang, Omar Almurad, Reizel J Pejana, Zachary A Morrison, Aditya Pandey, Louis-Philippe Picard, Mark Nitz, Adnan Sljoka, R Scott Prosser
Publikováno v:
eLife, Vol 11 (2022)
Cholesterol is a major component of the cell membrane and commonly regulates membrane protein function. Here, we investigate how cholesterol modulates the conformational equilibria and signaling of the adenosine A2A receptor (A2AR) in reconstituted p
Externí odkaz:
https://doaj.org/article/7e161692e49f49248619e079af5b4977
Autor:
Shuya Kate Huang, Louis-Philippe Picard, Rima S. M. Rahmatullah, Aditya Pandey, Ned Van Eps, Roger K. Sunahara, Oliver P. Ernst, Adnan Sljoka, R. Scott Prosser
Publikováno v:
Nature Structural & Molecular Biology. 30:502-511
Autor:
Xiaoying Huang, Peiliang Wu, Feifei Huang, Min Xu, Mayun Chen, Kate Huang, Guo-ping Li, Manhuan Xu, Dan Yao, Liangxing Wang
Publikováno v:
Journal of Biomedical Science, Vol 24, Iss 1, Pp 1-14 (2017)
Abstract Background Baicalin, an important flavonoid in Scutellaria baicalensis Georgi extracts, exerts a variety of pharmacological effects. In this study, we explored the effects of baicalin on chronic hypoxia-induced pulmonary arterial hypertensio
Externí odkaz:
https://doaj.org/article/1371dfe5b6344aa9af5b76d0b44502b5
Autor:
Tae Hun Kim, Michael L. Nosella, Nicolas Bolik-Coulon, Robert W. Harkness, Shuya Kate Huang, Lewis E. Kay
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Epigenetic modifications of chromatin play a critical role in regulating the fidelity of the genetic code and in controlling the translation of genetic information into the protein components of the cell. One key posttranslational modification is ace