Zobrazeno 1 - 10 of 11 pro vyhledávání: '"Katashi Matsumoto"'
4
Metabolism of (14C)zonisamide in rats, dogs and monkeys
Autor: Koji Yoshida, Hideo Furukawa, Toshihiko Fujii, Masahisa Hashimoto, Hisashi Miyazaki, Katashi Matsumoto
Publikováno v: Drug Metabolism and Pharmacokinetics. 4:411-418
Metabolite composition in rat plasma, tissues, urine and bile was studied by TLC radiochromatography after oral administration of [14C]zonisamide at 20 mg/kg. Metabolites excreted with dog and monkey urine were analyzed by TLC-radiochromatography and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e9f1960c77c309a84e76163fdcf4639b
https://doi.org/10.2133/dmpk.4.411
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5
Identification of rat urinary metabolites of zonisamide by TLC/SIMS
Autor: Katashi Matsumoto, Satoshi Arakawa, Koji Yoshida, Hisashi Miyazaki, Akira Kagemoto
Publikováno v: Drug Metabolism and Pharmacokinetics. 4:403-409
A combined use of deuterium labelling and recently developed scanning thinlayer chromatography/matrix-assisted-secondary-ion mass spectrometry(TLC/SIMS) was applied for identification of metabolites of zonisamide in rat urine. Zonisamide with deuteri
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6ea88e5921713d45b08ae90c8390296a
https://doi.org/10.2133/dmpk.4.403
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6
Disposition of125I-labeled recombinant human tumor necrosis factor in the tumor-bearing mouse
Autor: Akira Kagemoto, Shigeru Kurooka, Yasunobu Sohmura, Naoko Mikuriya, Yukiharu Matsui, Hisashi Miyazaki, Keiko Nambu, Masashi Nakao, Yoshinori Oh-E, Katsuji Nakano, Masahisa Hashimoto, Hideki Amejima, Katashi Matsumoto, Toshihiko Fujii, Noriyuki Sunahara
Publikováno v: Biotherapy. 1:7-18
Disposition of [125I]rHu-TNF was elucidated in BALB/c mice bearing Meth A fibrosarcoma 7 days after transplantation. After i.v. administration, [125I]rHu-TNF measured by radioactivity and immunoreactivity biphasically decreased in plasma. Tumor level
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7cc28c5d44a2a8ed53b705fb223e202
https://doi.org/10.1007/bf02170131
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7
Binding of sulfonamides to erythrocyte proteins and possible drug-drug interaction
Autor: Hideo Furukawa, Hideki Amejima, Hisashi Miyazaki, Toshihiko Fujii, Katashi Matsumoto, Masahisa Hashimoto
Publikováno v: Chemical and Pharmaceutical Bulletin. 37:2807-2810
The mode of binding of sulfonamides to erythrocyte proteins and possible drug-drug interaction between those compounds in erythrocytes resulting in changes in tissue levels were studied in rats using zonisamide (a novel antiepileptic agent possessing
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24a0ff65d5672d4c3b50706cf1188e5f
https://doi.org/10.1248/cpb.37.2807
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9
Autoradiographic and biochemical studies of drug distribution in the liver II. [35S] chlorpromazine and [14C] imipramine
Autor: Hisashi Miyazaki, Toshihiko Fujii, Masahisa Hashimoto, Keiko Nambu, Katashi Matsumoto
Publikováno v: European Journal of Drug Metabolism and Pharmacokinetics. 9:247-255
Whole body autoradiography revealed that the distribution pattern of [35S]chlorpromazine and [14C]imipramine in the mouse and rat liver was heterogeneous (or reticular) shortly after intravenous administration of the labeled agents and then became ho
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ce98372bb46a1846ef8518940091a0d
https://doi.org/10.1007/bf03189648
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