Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Katarzyna W. Janczak"'
Autor:
Michael N. Saunders, Claudia M. Rival, Mahua Mandal, Kayla Cramton, Laila M. Rad, Katarzyna W. Janczak, Laura A. Williams, Amogh R. Angadi, Jessica J. O’Konek, Lonnie D. Shea, Loren D. Erickson
Publikováno v:
Frontiers in Allergy, Vol 5 (2024)
IgE antibodies against the mammalian oligosaccharide allergen galactose-α-1,3-galactose (αGal) can result in a severe allergic disease known as alpha-gal syndrome (AGS). This syndrome, acquired by tick bites that cause αGal sensitization, leads to
Externí odkaz:
https://doaj.org/article/bbac7c05e8a044a5add0d3cf5958ff43
Autor:
Sonia Jangra, Jeffrey J. Landers, Gabriel Laghlali, Raveen Rathnasinghe, Prajakta Warang, Seok-Chan Park, Jessica. J. O’Konek, Gagandeep Singh, Katarzyna W. Janczak, Adolfo García-Sastre, Nandini Arya, Dilara Karadag, James R. Baker, Michael Schotsaert, Pamela T. Wong
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-18 (2023)
Abstract Multiple FDA-approved SARS-CoV-2 vaccines currently provide excellent protection against severe disease. Despite this, immunity can wane relatively fast, particularly in the elderly and novel viral variants capable of evading infection- and
Externí odkaz:
https://doaj.org/article/e0f2e171cb6d49a6bff9be7e335d5f23
Autor:
Kevin R. Hughes, Michael N. Saunders, Jeffrey J. Landers, Katarzyna W. Janczak, Hamza Turkistani, Laila M. Rad, Stephen D. Miller, Joseph R. Podojil, Lonnie D. Shea, Jessica J. O'Konek
Publikováno v:
Frontiers in Allergy, Vol 3 (2022)
Food allergy is a growing health concern worldwide. Current allergen-specific immunotherapy (AIT) approaches require frequent dosing over extended periods of time and may induce anaphylaxis due to allergen-effector cell interactions. A critical need
Externí odkaz:
https://doaj.org/article/3c967ed4fa074b00a0660420dcd3c09b
Autor:
Sonia Jangra, Jeffrey J. Landers, Raveen Rathnasinghe, Jessica J. O’Konek, Katarzyna W. Janczak, Marilia Cascalho, Andrew A. Kennedy, Andrew W. Tai, James R. Baker, Michael Schotsaert, Pamela T. Wong
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Several SARS-CoV-2 vaccines have received EUAs, but many issues remain unresolved, including duration of conferred immunity and breadth of cross-protection. Adjuvants that enhance and shape adaptive immune responses that confer broad protection again
Externí odkaz:
https://doaj.org/article/02e1fb5d10c442a983749ef606a66613
Autor:
Mohammad Farazuddin, Jeffrey J. Landers, Katarzyna W. Janczak, Hayley K. Lindsey, Fred D. Finkelman, James R. Baker, Jessica J. O’Konek
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
We have demonstrated that intranasal immunotherapy with allergens formulated in a nanoemulsion (NE) mucosal adjuvant suppresses Th2/IgE-mediated allergic responses and protects from allergen challenge in murine food allergy models. Protection conferr
Externí odkaz:
https://doaj.org/article/cd077d7e2db64de48475073d268ae5d2
Autor:
Pamela T. Wong, Megan E. Ermler, Jessica J. O’Konek, Rachel Sun, Peter H. Goff, Jeffrey J. Landers, Matthew J. Ruge, Alyssa Sebring, Katarzyna W. Janczak, Weina Sun, James R. Baker
Publikováno v:
Molecular Pharmaceutics. 18:679-698
Current influenza virus vaccines are focused on humoral immunity and are limited by the short duration of protection, narrow cross-strain efficacy, and suboptimal immunogenicity. Here, we combined two chemically and biologically distinct adjuvants, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e56a6312ebbe4cb8428a6ecee2e15fb0
https://doi.org/10.1021/acs.molpharmaceut.0c00315
https://doi.org/10.1021/acs.molpharmaceut.0c00315
Autor:
Jeffrey J Landers, Katarzyna W Janczak, Akhilesh Kumar Shakya, Vladimir Zarnitsyn, Samirkumar R Patel, James R Baker, Harvinder Singh Gill, Jessica J O'Konek
Publikováno v:
Immunotherapy
Aim: Epicutaneous immunotherapy (EPIT) with peanut has been demonstrated to be safe but efficacy may be limited by allergen uptake through the skin barrier. To enhance allergen uptake into the skin, the authors used peanut-coated microneedles and com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31d5a42fac84b3ab7dc22be7fc8a9310
https://europepmc.org/articles/PMC9043875/
https://europepmc.org/articles/PMC9043875/
Autor:
Pamela T Wong, Pascale R Leroueil, Douglas M Smith, Susan Ciotti, Anna U Bielinska, Katarzyna W Janczak, Catherine H Mullen, Jeffrey V Groom, Erin M Taylor, Crystal Passmore, Paul E Makidon, Jessica J O'Konek, Andrzej Myc, Tarek Hamouda, James R Baker
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126120 (2015)
Vaccine adjuvants have been reported to induce both mucosal and systemic immunity when applied to mucosal surfaces and this dual response appears important for protection against certain pathogens. Despite the potential advantages, however, no mucosa
Externí odkaz:
https://doaj.org/article/4084c3c916ea48baa41149fcafb14c47
Autor:
Katarzyna W. Janczak, Andrew J. Rasky, James R. Baker, Jeffrey J. Landers, Nicholas W. Lukacs, Jessica J. O’Konek, Tiffanie D. Totten
Publikováno v:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical ImmunologyREFERENCES. 51(10)
Background Atopic diseases are an increasing problem that involve both immediate hypersensitivity reactions mediated by IgE and unique cellular inflammation. Many forms of specific immunotherapy involve the administration of allergen to suppress alle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5e59aa65b117f723084133bc85ced74
https://pubmed.ncbi.nlm.nih.gov/33999457
https://pubmed.ncbi.nlm.nih.gov/33999457
Autor:
Jessica J. O’Konek, Hayley K. Lindsey, Mohammad Farazuddin, Fred D. Finkelman, Jeffrey J. Landers, Katarzyna W. Janczak, James R. Baker
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology
We have demonstrated that intranasal immunotherapy with allergens formulated in a nanoemulsion (NE) mucosal adjuvant suppresses Th2/IgE-mediated allergic responses and protects from allergen challenge in murine food allergy models. Protection conferr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd6a714e83110345f0ea2370ab2e406f
https://doi.org/10.3389/fimmu.2021.599296
https://doi.org/10.3389/fimmu.2021.599296