Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Katarzyna Taylor"'
Autor:
Magdalena Derbis, Emre Kul, Daria Niewiadomska, Michał Sekrecki, Agnieszka Piasecka, Katarzyna Taylor, Renate K. Hukema, Oliver Stork, Krzysztof Sobczak
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Fragile X-associated tremor/ataxia syndrome is a neurodegenerative disease caused by toxic RNA containing expanded CGG repeats. Here, the authors show that synthetic oligonucleotides targeting the RNA repeats decrease the pleiotropic effect of this t
Externí odkaz:
https://doaj.org/article/c6498e46fb154abdbc4b08a40653c26d
Autor:
Łukasz J. Sznajder, Marina M. Scotti, Jihae Shin, Katarzyna Taylor, Franjo Ivankovic, Curtis A. Nutter, Faaiq N. Aslam, S. H. Subramony, Laura P. W. Ranum, Maurice S. Swanson
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
The activity of the RNA splicing factor MBNL1 is altered in myotonic dystrophy (DM) patients. Here the authors characterize the thymic phenotype of Mbnl1 knockout mice, including developmental defects, transcriptome changes, and RNA mis-splicing of t
Externí odkaz:
https://doaj.org/article/d633908c2a2e467aa55689a91243f33f
Autor:
Karol Czubak, Katarzyna Taylor, Agnieszka Piasecka, Krzysztof Sobczak, Katarzyna Kozlowska, Anna Philips, Saam Sedehizadeh, J. David Brook, Marzena Wojciechowska, Piotr Kozlowski
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Splicing aberrations induced as a consequence of the sequestration of muscleblind-like splicing factors on the dystrophia myotonica protein kinase transcript, which contains expanded CUG repeats, present a major pathomechanism of myotonic dystrophy t
Externí odkaz:
https://doaj.org/article/f9a23745cc8a47ba826633b93a12d216
Autor:
Katarzyna Taylor, Krzysztof Sobczak
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 14, p 5161 (2020)
Alternative splicing is a highly sophisticated process, playing a significant role in posttranscriptional gene expression and underlying the diversity and complexity of organisms. Its regulation is multilayered, including an intrinsic role of RNA str
Externí odkaz:
https://doaj.org/article/4227cf42ca56404894a93da509b44e3e
Autor:
Chikara Dohno, Daria Niewiadomska, Anna Baud, Katarzyna Taylor, Krzysztof Sobczak, Patryk Konieczny, Agnieszka Walczak, Ewa Stepniak-Konieczna, Sanjukta Mukherjee, Agnieszka Piasecka, Kazuhiko Nakatani
Publikováno v:
Nucleic Acids Research
Fragile X-associated tremor/ataxia syndrome (FXTAS) is a late-onset neurodegenerative disorder caused by a limited expansion of CGG repeats in the FMR1 gene. Degeneration of neurons in FXTAS cell models can be triggered by accumulation of polyglycine
Autor:
Jihae Shin, Curtis A. Nutter, Maurice S. Swanson, S. H. Subramony, Łukasz J. Sznajder, Franjo Ivankovic, Laura P.W. Ranum, Katarzyna Taylor, Marina M. Scotti, Faaiq N. Aslam
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Nature Communications
Nature Communications
The thymus is a primary lymphoid organ that plays an essential role in T lymphocyte maturation and selection during development of one arm of the mammalian adaptive immune response. Although transcriptional mechanisms have been well documented in thy
Autor:
Jinxing Li, Masayuki Nakamori, Jun Matsumoto, Katarzyna Taylor, Chikara Dohno, Agnieszka Kiliszek, Asako Murata, Kazuhiko Nakatani, Krzysztof Sobczak
Publikováno v:
Chemistry – A European Journal. 24:18115-18122
Expanded r(CUG) repeats are the cause of the neurological disorder myotonic dystrophy type 1 (DM1). The pathological features of DM1 include the formation of ribonuclear foci containing expanded r(CUG) repeats, which sequester the MBNL1 protein and l
Autor:
Agnieszka Piasecka, Magdalena Derbis, Oliver Stork, Katarzyna Taylor, Renate K. Hukema, Michał Sekrecki, Emre Kul, Daria Niewiadomska, Krzysztof Sobczak
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Nature Communications, 12(1):1265. Nature Publishing Group
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Nature Communications, 12(1):1265. Nature Publishing Group
Fragile X-associated tremor/ataxia syndrome (FXTAS) is an incurable neurodegenerative disorder caused by expansion of CGG repeats in the FMR1 5’UTR. The RNA containing expanded CGG repeats (rCGGexp) causes cell damage by interaction with complement
Autor:
Krzysztof Sobczak, Katarzyna Taylor
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 5161, p 5161 (2020)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Alternative splicing is a highly sophisticated process, playing a significant role in posttranscriptional gene expression and underlying the diversity and complexity of organisms. Its regulation is multilayered, including an intrinsic role of RNA str
Autor:
Julia E. Weigand, Sandra Fischer, Antonella Di Liddo, Jamina S. Gerhardus, Katarzyna Taylor, Kathi Zarnack, Krzysztof Sobczak
Publikováno v:
RNA
Hypoxia is a hallmark of solid cancers, supporting proliferation, angiogenesis, and escape from apoptosis. There is still limited understanding of how cancer cells adapt to hypoxic conditions and survive. We analyzed transcriptome changes of human lu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96124d568884302ffc3deacae58f002f
https://europepmc.org/articles/PMC7161353/
https://europepmc.org/articles/PMC7161353/