Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Katarzyna Supruniuk"'
Autor:
Iwona Radziejewska, Katarzyna Supruniuk, Katarzyna Jakimiuk, Michał Tomczyk, Anna Bielawska, Anna Galicka
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13036 (2023)
Specific changes in mucin-type O-glycosylation are common for many cancers, including gastric ones. The most typical alterations include incomplete synthesis of glycan structures, enhanced expression of truncated O-glycans (Tn, T antigens and their s
Externí odkaz:
https://doaj.org/article/dea45cdf8e3b499baebad529329b5e7a
Publikováno v:
Translational Oncology, Vol 18, Iss , Pp 101348- (2022)
The membrane-bound MUC1 mucin is overexpressed and aberrantly glycosylated in many epithelium origin cancers. One of the promising strategies in cancer therapy is combining monoclonal antibodies against cancer related antigens, like MUC1, with chemot
Externí odkaz:
https://doaj.org/article/9517b4d4367a4c07b3870fd51e706c5d
Autor:
Iwona Radziejewska, Katarzyna Supruniuk, Michał Tomczyk, Wiktoria Izdebska, Małgorzata Borzym-Kluczyk, Anna Bielawska, Krzysztof Bielawski, Anna Galicka
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 15, p 8602 (2022)
Abnormal glycosylation of cancer cells is considered a key factor of carcinogenesis related to growth, proliferation, migration and invasion of tumor cells. Many plant-based polyphenolic compounds reveal potential anti-cancer properties effecting cel
Externí odkaz:
https://doaj.org/article/fdfd6bf55f274765ab92146dadcabead
Publikováno v:
Pharmaceuticals, Vol 14, Iss 10, p 973 (2021)
Afzelin demonstrates anti-inflammatory and anti-cancer properties. Our purpose was to assess its influence on apoptosis, Bax, caspases, MUC1, cancer-related carbohydrate antigens, enzymes participating in their formation, and galectin-3 in AGS gastri
Externí odkaz:
https://doaj.org/article/a78b4a36786547c299432c15e37ddf8d
Publikováno v:
Pharmaceutics, Vol 13, Iss 7, p 968 (2021)
MUC1 mucin is a transmembrane glycoprotein aberrantly overexpressed and underglycosylated in most epithelium origin cancers. Combining chemotherapeutics with monoclonal antibodies toward cancer-related antigens is one of the new strategies in cancer
Externí odkaz:
https://doaj.org/article/c715c4b5794c4fdfb7fab7af5bedf2ca
Publikováno v:
Pharmaceuticals
Pharmaceuticals, Vol 14, Iss 973, p 973 (2021)
Volume 14
Issue 10
Pharmaceuticals, Vol 14, Iss 973, p 973 (2021)
Volume 14
Issue 10
Afzelin demonstrates anti-inflammatory and anti-cancer properties. Our purpose was to assess its influence on apoptosis, Bax, caspases, MUC1, cancer-related carbohydrate antigens, enzymes participating in their formation, and galectin-3 in AGS gastri
Publikováno v:
Pharmaceutics
Volume 13
Issue 7
Pharmaceutics, Vol 13, Iss 968, p 968 (2021)
Volume 13
Issue 7
Pharmaceutics, Vol 13, Iss 968, p 968 (2021)
MUC1 mucin is a transmembrane glycoprotein aberrantly overexpressed and underglycosylated in most epithelium origin cancers. Combining chemotherapeutics with monoclonal antibodies toward cancer-related antigens is one of the new strategies in cancer
Autor:
B. Popławska, Jolanta Nazaruk, A. Galicka, Iwona Radziejewska, Ewa Karna, Anna Bielawska, Katarzyna Supruniuk
Publikováno v:
Biomedicine & Pharmacotherapy. 107:397-407
Rosmarinic acid (RA) is a natural phenylpropanoid with numerous pharmacological activities. Because of limited studies of the effects of RA action in gastric cancer cells we examined how 100 and 200 μM acid influences MMPs, TIMPs, collagen, MUC1 and
Publikováno v:
International Journal of Oncology
Mucin 1 (MUC1) is a membrane‑bound, highly glycosylated protein that is overexpressed in all stages of malignant transformation. Overexpression of MUC1 together with loss of polarization and hypoglycosylation are associated with resistance to apopt
Publikováno v:
European Journal of Pharmacology. 902:174119
MUC1 seems to be promising target in cancer cells due to its abundant and specifically altered expression as well as differential distribution pattern relative to normal tissues. Rosmarinic acid (RA) is a natural, polyphenolic compound with pharmacol