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pro vyhledávání: '"Katarzyna Soczek"'
Autor:
Elizabeth C. Stahl, Jennifer K. Sabo, Min Hyung Kang, Ryan Allen, Elizabeth Applegate, Shin Eui Kim, Yoonjin Kwon, Anmol Seth, Nicholas Lemus, Viviana Salinas-Rios, Katarzyna Soczek, Marena Trinidad, Linda T. Vo, Chris Jeans, Anna Wozniak, Timothy Morris, Athen Kimberlin, Thomas Foti, David F. Savage, Jennifer A. Doudna
Transient delivery of CRISPR-Cas9 ribonucleoproteins (RNPs) into the central nervous system (CNS) for therapeutic genome editing could avoid limitations of viral vector-based delivery including cargo capacity, immunogenicity, and cost. Here we tested
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5f4275a42165337bdc6ac4459130f9b
https://doi.org/10.1101/2023.04.13.536294
https://doi.org/10.1101/2023.04.13.536294
Autor:
Nicholas O. Stevers, Carter Barger, Olivia Lenzo, Chibo Hong, Katarzyna Soczek, Samuel H. Wu, Andrew M. McKinney, Abigail Suwala, Jennifer A. Doudna, Joseph F. Costello
Publikováno v:
Cancer Research. 82:2302-2302
Ninety percent of human tumors reactivate telomerase reverse transcriptase (TERT) to achieve cellular immortality. The route to immortality found in over 50 cancer types is mutation of the TERT promoter (TERTp) mutations. Studies in glioblastoma have