Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Katarzyna Popiolek-Barczyk"'
Autor:
Marco Oggioni, Domenico Mercurio, Denise Minuta, Stefano Fumagalli, Katarzyna Popiolek-Barczyk, Marina Sironi, Agata Ciechanowska, Stefania Ippati, Daiana De Blasio, Carlo Perego, Joanna Mika, Cecilia Garlanda, Maria-Grazia De Simoni
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Long pentraxin PTX3, a pattern recognition molecule involved in innate immune responses, is upregulated by pro-inflammatory stimuli, contributors to secondary damage in traumatic brain injury (TBI). We analyzed PTX3 involvement in mice subje
Externí odkaz:
https://doaj.org/article/ab84c6e775b8498fa19cd39f64b559e4
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 7 (2017)
Botulinum neurotoxin type A (BoNT/A) and minocycline are potent drugs used in clinical therapies. The primary molecular mechanism of BoNT/A is the cleavage of SNARE proteins, which prevents cells from releasing neurotransmitters from vesicles, while
Externí odkaz:
https://doaj.org/article/63082e04ea25480c84f08d1727b6f23f
Publikováno v:
Neural Plasticity, Vol 2017 (2017)
Neuropathic pain is relatively less responsive to opioids than other types of pain, which is possibly due to a disrupted opioid system partially caused by the profound microglial cell activation that underlines neuroinflammation. We demonstrated that
Externí odkaz:
https://doaj.org/article/c0648833d6194d9c894d78109791b584
Publikováno v:
Toxins, Vol 10, Iss 4, p 145 (2018)
Neuropathic pain represents a significant clinical problem because it is a chronic condition often refractory to available therapy. Therefore, there is still a strong need for new analgesics. Botulinum neurotoxin A (BoNT/A) is used to treat a variety
Externí odkaz:
https://doaj.org/article/243e3b31301e47c9b08e05c4d3ee6064
Autor:
Natalia Malek, Katarzyna Popiolek-Barczyk, Joanna Mika, Barbara Przewlocka, Katarzyna Starowicz
Publikováno v:
Neural Plasticity, Vol 2015 (2015)
Microglial activation is a polarized process divided into potentially neuroprotective phenotype M2 and neurotoxic phenotype M1, predominant during chronic neuroinflammation. Endocannabinoid system provides an attractive target to control the balance
Externí odkaz:
https://doaj.org/article/39ed4730cf9c4f2c8d8ded9d8601db30
Autor:
Ewelina Rojewska, Katarzyna Popiolek-Barczyk, Natalia Kolosowska, Anna Piotrowska, Magdalena Zychowska, Wioletta Makuch, Barbara Przewlocka, Joanna Mika
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0138583 (2015)
Neuropathic pain treatment remains challenging due to ineffective therapy and resistance to opioid analgesia. Mitogen-activated protein kinase kinase (MAPKK) have been identified as the crucial regulators of pro- and antinociceptive factors. We used
Externí odkaz:
https://doaj.org/article/8192a8cd33564c4f9ca66d530c18b6b6
Autor:
Katarzyna Popiolek-Barczyk, Natalia Kolosowska, Anna Piotrowska, Wioletta Makuch, Ewelina Rojewska, Agnieszka M. Jurga, Dominika Pilat, Joanna Mika
Publikováno v:
Neural Plasticity, Vol 2015 (2015)
Neuropathic pain treatment remains a challenge because pathomechanism is not fully understood. It is believed that glial activation and increased spinal nociceptive factors are crucial for neuropathy. We investigated the effect of parthenolide (PTL)
Externí odkaz:
https://doaj.org/article/5bf83e6484d94706aac5775f91f384fe
Autor:
Joanna Mika, Katarzyna Popiolek-Barczyk, Ewelina Rojewska, Wioletta Makuch, Katarzyna Starowicz, Barbara Przewlocka
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104420 (2014)
The analgesic effect of delta-opioid receptor (DOR) ligands in neuropathic pain is not diminished in contrast to other opioid receptor ligands, which lose their effectiveness as analgesics. In this study, we examine whether this effect is related to
Externí odkaz:
https://doaj.org/article/40f9a48929dc4a749c23b846615a1931
Autor:
Cecilia Garlanda, Stefano Fumagalli, Agata Ciechanowska, Marco Oggioni, Carlo Perego, Maria Grazia De Simoni, Daiana De Blasio, Stefania Ippati, Denise Minuta, Marina Sironi, Katarzyna Popiolek-Barczyk, Joanna Mika, Domenico Mercurio
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Scientific Reports
Scientific Reports
Long pentraxin PTX3, a pattern recognition molecule involved in innate immune responses, is upregulated by pro-inflammatory stimuli, contributors to secondary damage in traumatic brain injury (TBI). We analyzed PTX3 involvement in mice subjected to c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5031c64a8c05f9eafb54ff982c664b5
https://doaj.org/article/ab84c6e775b8498fa19cd39f64b559e4
https://doaj.org/article/ab84c6e775b8498fa19cd39f64b559e4
Autor:
Maria Grazia De Simoni, Katarzyna Popiolek-Barczyk, Marco Oggioni, Joanna Mika, Domenico Mercurio, Katarzyna Pawlik, Agata Ciechanowska, Katarzyna Ciapała
Publikováno v:
Pharmacological Reports
Background Every year, millions of people suffer from various forms of traumatic brain injury (TBI), and new approaches with therapeutic potential are required. Although chemokines are known to be involved in brain injury, the importance of X-C motif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::537914962950dc89283e1f786e92b39b
http://europepmc.org/articles/PMC7704520
http://europepmc.org/articles/PMC7704520