Výsledky vyhledávání - "Katarzyna Piwoni"

Akademický článek

4-Week repeated dose rat GLP toxicity study of oncolytic ECHO-7 virus Rigvir administered intramuscularly with a 4-week recovery period

Autor: Katarzyna Piwoni, Gilta Jaeckel, Agnija Rasa, Pēteris Alberts

Publikováno v: Toxicology Reports, Vol 8, Iss , Pp 230-238 (2021)

The oncolytic ECHO-7 virus Rigvir was registered in Latvia in 2004 and later in Georgia, Armenia and Uzbekistan. No severe adverse events have been observed. During drug development good laboratory practice (GLP) pre-clinical toxicology studies are g

Externí odkaz: https://doaj.org/article/2093913a2eed4b468b9173a437acf750

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4-Week repeated dose rat GLP toxicity study of oncolytic ECHO-7 virus Rigvir administered intramuscularly with a 4-week recovery period

Autor: Pēteris Alberts, Katarzyna Piwoni, Agnija Rasa, Gilta Jaeckel

Publikováno v: Toxicology Reports
Toxicology Reports, Vol 8, Iss, Pp 230-238 (2021)

Highlights • 4-week repeated dose rat GLP toxicology study with the oncolytic ECHO-7 virus Rigvir. • No unscheduled deaths, adverse clinical signs, changes in body weight or food intake. • Rigvir was biodistributed to the spleen. • Rigvir was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d8ce92db34456e18a248c9a5d7390dd
https://pubmed.ncbi.nlm.nih.gov/33537211

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