Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Katarzyna Modzelewska"'
Autor:
Katarzyna Modzelewska, Elena F. Boer, Timothy L. Mosbruger, Daniel Picard, Daniela Anderson, Rodney R. Miles, Mitchell Kroll, William Oslund, Theodore J. Pysher, Joshua D. Schiffman, Randy Jensen, Cicely A. Jette, Annie Huang, Rodney A. Stewart
Publikováno v:
Cell Reports, Vol 17, Iss 5, Pp 1255-1264 (2016)
Summary: Malignant brain tumors are the leading cause of cancer-related deaths in children. Primitive neuroectodermal tumors of the CNS (CNS-PNETs) are particularly aggressive embryonal tumors of unknown cellular origin. Recent genomic studies have c
Externí odkaz:
https://doaj.org/article/d49d49aa85484923af1ac852839c57c6
Autor:
Katarzyna Modzelewska, Amara Lauritzen, Stefan Hasenoeder, Louise Brown, John Georgiou, Nadeem Moghal
Publikováno v:
PLoS Biology, Vol 11, Iss 1, p e1001465 (2013)
Metazoans display remarkable conservation of gene families, including growth factors, yet somehow these genes are used in different ways to generate tremendous morphological diversity. While variations in the magnitude and spatio-temporal aspects of
Externí odkaz:
https://doaj.org/article/cbfa47c7c74a41f78b11327e7d2db219
Autor:
Trudy G. Oliver, Ralph J. DeBerardinis, John S. Bomalaski, Sabina C. Cosulich, David H. Lum, Jason Gertz, Nicholas T. Ingolia, Guoying Wang, Katarzyna Modzelewska, Marek Kudla, Zeping Hu, Jeffery M. Vahrenkamp, Kristofer C. Berrett, Matthew R. Guthrie, Sophia S. Schuman, Younjee Lee, Anandaroop Mukhopadhyay, Abbie S. Ireland, Fang Huang, Sarah J. Wait, Milind D. Chalishazar
Purpose:Small-cell lung cancer (SCLC) has been treated clinically as a homogeneous disease, but recent discoveries suggest that SCLC is heterogeneous. Whether metabolic differences exist among SCLC subtypes is largely unexplored. In this study, we ai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ba64efad98c180164a0021364264b4f
https://doi.org/10.1158/1078-0432.c.6528816.v1
https://doi.org/10.1158/1078-0432.c.6528816.v1
Autor:
Trudy G. Oliver, Ralph J. DeBerardinis, John S. Bomalaski, Sabina C. Cosulich, David H. Lum, Jason Gertz, Nicholas T. Ingolia, Guoying Wang, Katarzyna Modzelewska, Marek Kudla, Zeping Hu, Jeffery M. Vahrenkamp, Kristofer C. Berrett, Matthew R. Guthrie, Sophia S. Schuman, Younjee Lee, Anandaroop Mukhopadhyay, Abbie S. Ireland, Fang Huang, Sarah J. Wait, Milind D. Chalishazar
Supplemental Figures 1-6 and Supplemental Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4d10b0d076fe169e9776a93090a74b5
https://doi.org/10.1158/1078-0432.22474530.v1
https://doi.org/10.1158/1078-0432.22474530.v1
Autor:
Zannel Blanchard, Spencer Arnesen, Jeffery M. Vahrenkamp, Adriana C. Rodriguez, Elke A. Jarboe, Callie Brown, Katarzyna Modzelewska, David H. Lum, Jason Gertz
Activating estrogen receptor alpha (ER) mutations are present in primary endometrial and metastatic breast cancers, promoting estrogen-independent activation of the receptor. Functional characterizations in breast cancer have established unique molec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::902e72d462966d7748afb6e23f2e1021
https://doi.org/10.1101/2022.06.13.495977
https://doi.org/10.1101/2022.06.13.495977
Publikováno v:
Development (Cambridge, England). 147(14)
Long-term survival of an animal species depends on development being robust to environmental variations and climate changes. We used C. elegans to study how mechanisms that sense environmental changes trigger adaptive responses that ensure animals de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe90c7f9ae0bfdacc7026af1992e5fac
https://pubmed.ncbi.nlm.nih.gov/32586974
https://pubmed.ncbi.nlm.nih.gov/32586974
Autor:
Fang Huang, John S. Bomalaski, Guoying Wang, Marek Kudla, Milind D. Chalishazar, Younjee Lee, Matthew R. Guthrie, Sarah J. Wait, Nicholas T. Ingolia, Katarzyna Modzelewska, Kristofer C. Berrett, Sabina Cosulich, Abbie S. Ireland, Trudy G. Oliver, Jeffery M. Vahrenkamp, David H. Lum, Anandaroop Mukhopadhyay, Ralph J. DeBerardinis, Zeping Hu, Sophia S. Schuman, Jason Gertz
Purpose: Small-cell lung cancer (SCLC) has been treated clinically as a homogeneous disease, but recent discoveries suggest that SCLC is heterogeneous. Whether metabolic differences exist among SCLC subtypes is largely unexplored. In this study, we a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fa0a19a03c6c7493d3666b9b8108cce
https://europepmc.org/articles/PMC6697617/
https://europepmc.org/articles/PMC6697617/
Autor:
Elena F. Boer, Douglas Grossman, Mattie J. Casey, Laura Jimenez, Daniela Anderson, Katarzyna Modzelewska, James R. Goodman, Rodney A. Stewart
Publikováno v:
Journal of Visualized Experiments : JoVE
Tumor cell transplantation is an important technique to define the mechanisms controlling cancer cell growth, migration, and host response, as well as to assess potential patient response to therapy. Current methods largely depend on using syngeneic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb051f78dedff09adeb316503903d548
https://doi.org/10.3791/55712-v
https://doi.org/10.3791/55712-v
Autor:
Tong Liu, Nadeem Moghal, Douglas Grossman, Daniel V. LaBarbera, Katarzyna Modzelewska, Manjinder Kaur, Mary Kay Harper, Chris M. Ireland, Amanda I. Glazar, Scott K. Kuwada, Phillip D. Gray
Publikováno v:
Anticancer Drugs
Apoptosis is important for normal development and removal of damaged cells. Evasion of apoptosis by cancer cells is one of the key characteristics of many tumor types. Thus, discovering agents that promote apoptosis in tumor cells could have great th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcde6cc85aec2c0f6a8890156b2d3803
https://europepmc.org/articles/PMC7992254/
https://europepmc.org/articles/PMC7992254/
Autor:
Annie Huang, Elena F. Boer, Randy L. Jensen, Katarzyna Modzelewska, Rodney A. Stewart, Theodore Pysher, Rodney R. Miles, Joshua D. Schiffman, Cicely A. Jette, Daniel Picard
Publikováno v:
Neuro-Oncology. 17:iii33-iii33
Modeling cancer in zebrafish is a rapidly growing area of research due to unique imaging and drug screening attributes of the system, as well as cost. While over 20 different zebrafish cancer models have been established, no genetically engineered mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9332fead59e2f7dc0b544b853daa1433
https://doi.org/10.1093/neuonc/nov061.134
https://doi.org/10.1093/neuonc/nov061.134