Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Katarzyna Mercik"'
Autor:
Paulina Wyrembek, Jerzy W. Mozrzymas, Marcin Szczot, Katarzyna Szczuraszek, Katarzyna Mercik, Federica Pollastro, Giovanni Appendino, Katarzyna Lebida
Publikováno v:
British Journal of Pharmacology. 160:1302-1315
Background and purpose: Oenanthotoxin (OETX), a polyacetylenic alcohol from plants of the genus Oenanthe, has recently been identified as potent inhibitor of GABA-evoked currents. However, the effects of OETX on the inhibitory postsynaptic currents (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6469fa164deee66f4eacd3bcf3424993
https://doi.org/10.1111/j.1476-5381.2010.00644.x
https://doi.org/10.1111/j.1476-5381.2010.00644.x
Autor:
Paulina Wyrembek, Katarzyna Lebida, Katarzyna Mercik, Tomasz Wójtowicz, Michał Piast, Jerzy W. Mozrzymas
Publikováno v:
The Journal of Physiology. 585:29-46
Benzodiazepines (BDZs) are known to increase the amplitude and duration of IPSCs. Moreover, at low [GABA], BDZs strongly enhance GABAergic currents suggesting the up-regulation of agonist binding while their action on gating remains a matter of debat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::460198bdfb4869ff105289c9bb788bdb
https://doi.org/10.1113/jphysiol.2007.143602
https://doi.org/10.1113/jphysiol.2007.143602
Publikováno v:
NeuroReport. 18:781-785
Benzodiazepines are known to act by enhancing the effect of gamma-aminobutyric acid-A receptor agonists. Positive modulation by benzodiazepines is typically ascribed to upregulation of agonist binding affinity but their effect on gamma-aminobutyric a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c15f920830a01904f3f9b9a4585cee46
https://doi.org/10.1097/wnr.0b013e3280c1e2fb
https://doi.org/10.1097/wnr.0b013e3280c1e2fb
Publikováno v:
Neuropharmacology. 51:305-314
Recently, we have reported that extracellular protons allosterically modulated neuronal GABA(A) receptors [Mozrzymas, J.W., Zarnowska, E.D., Pytel, M., Mercik, K., 2003a. Modulation of GABA(A) receptors by hydrogen ions reveals synaptic GABA transien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7d9562f10784d978a7816a399083cf9
https://doi.org/10.1016/j.neuropharm.2006.03.023
https://doi.org/10.1016/j.neuropharm.2006.03.023
Publikováno v:
British Journal of Pharmacology. 148:413-422
Cyclodextrins (CDs) are nanostructures widely applied in biotechnology and chemistry. Owing to partially hydrophobic character, CDs interact with biological membranes. While the mechanisms of CDs interactions with lipids were widely studied, their ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75c31a572c240d3f7f44950027fefd77
https://doi.org/10.1038/sj.bjp.0706747
https://doi.org/10.1038/sj.bjp.0706747
Publikováno v:
Neuropharmacology. 50:143-153
The kinetics of GABAergic currents in neurons is known to be modulated by the membrane voltage but the underlying mechanisms have not been fully explored. In particular, the impact of membrane potential on the GABAA receptor gating has not been eluci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::140207f52678ac2b50943d7b01e5f627
https://doi.org/10.1016/j.neuropharm.2005.08.001
https://doi.org/10.1016/j.neuropharm.2005.08.001
Publikováno v:
NeuroReport. 16:1951-1954
Recent studies have indicated that changes in extracellular pH and in membrane voltage affect the gamma-amino-n-butyric acid type A receptor gating mainly by altering desensitization and binding. To test whether the effects of membrane potential and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10631fb7cb07fa24e279551b5b7b3d12
https://doi.org/10.1097/01.wnr.0000187631.83751.9b
https://doi.org/10.1097/01.wnr.0000187631.83751.9b
Publikováno v:
Neuroscience Letters. 352:195-198
Neuronal γ-aminobutyric acid (GABA)A receptors are extremely heterogeneous and therefore GABAergic currents represent responses of unknown mixture of receptor subtypes. Expression of recombinant receptors in foreign cells allows to investigate a def
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f5602c1326b43cb2c714d3d695befc4
https://doi.org/10.1016/j.neulet.2003.08.060
https://doi.org/10.1016/j.neulet.2003.08.060
Publikováno v:
European Journal of Neuroscience. 16:2253-2259
Current responses to ultrafast gamma-aminobutyric acid (GABA) applications were recorded from excised patches in rat hippocampal neurons to study the gating properties of GABA(A) receptors at GABA concentrations close to saturating ones and higher. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54294b45d427698ea7fd59ac492b2229
https://doi.org/10.1046/j.1460-9568.2002.02307.x
https://doi.org/10.1046/j.1460-9568.2002.02307.x
Autor:
Paulina Wyrembek, Marcin Wawrzyniak, Nikolay I. Medvedev, Leszek Kaczmarek, Grzegorz M. Wilczynski, Dominique Muller, Marcin Szczot, Jerzy W. Mozrzymas, Ewa Wilczek, Katarzyna Mercik, Mathias De Roo, Michael G. Stewart, Jakub Wlodarczyk, Przemyslaw Alot, Werner Zuschratter, Piotr Michaluk
Publikováno v:
Journal of Cell Science, Vol. 124, No Pt 19 (2011) pp. 3369-80
Journal of cell science
Journal of Cell Science; Vol 124
Journal of cell science
Journal of Cell Science; Vol 124
An increasing body of data has shown that matrix metalloproteinase-9 (MMP-9), an extracellularly acting, Zn2+-dependent endopeptidase, is important not only for pathologies of the central nervous system but also for neuronal plasticity. Here, we use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b15b6df20bdee0d90b3278c35c334769
https://archive-ouverte.unige.ch/unige:25597
https://archive-ouverte.unige.ch/unige:25597
