Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Katarzyna Malenczyk"'
Autor:
Katarzyna Malenczyk, Edit Szodorai, Robert Schnell, Gert Lubec, Gábor Szabó, Tomas Hökfelt, Tibor Harkany
Publikováno v:
Molecular Metabolism, Vol 14, Iss , Pp 108-120 (2018)
Objective: Specification of endocrine cell lineages in the developing pancreas relies on extrinsic signals from non-pancreatic tissues, which initiate a cell-autonomous sequence of transcription factor activation and repression switches. The steps in
Externí odkaz:
https://doaj.org/article/9fd66cccfe64485eb10dc1f6a53af067
Publikováno v:
The EMBO Journal
Autor:
Jan Mulder, Tibor Harkany, Katarzyna Malenczyk, Tomas Hökfelt, Fatima Girach, Mathias Uhlén, Masahiko Watanabe, Lotta Borgius, Ming-Dong Zhang, Valentina Cinquina, Csaba Adori, Changgeng Peng, Peter Löw, Patrik Ernfors, Ole Kiehn, Jie Su, Nicholas Mitsios
Publikováno v:
Journal of Clinical Investigation
Pain signals are transmitted by multisynaptic glutamatergic pathways. Their first synapse between primary nociceptors and excitatory spinal interneurons gates the sensory load. In this pathway, glutamate release is orchestrated by Ca2+-sensor protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::215be8df6a9fa497bc110f3674c0ec09
https://europepmc.org/articles/PMC6118643/
https://europepmc.org/articles/PMC6118643/
Autor:
Tibor Harkany, Ilenia Severi, Roman A. Romanov, Günther Sperk, Tamas L. Horvath, Gloria Arque, János Hanics, Alán Alpár, Marco Benevento, Solomiia Korchynska, Zsófia Hevesi, Christian Pifl, Ramon O. Tasan, Gergely Zachar, Katarzyna Malenczyk, Jessica Perugini, Patrick Leitgeb, Andras G. Miklosi, Gábor Szabó, Ferenc Erdélyi, Zoltán Máté, Antonio Giordano, Tomas Hökfelt, Erik Keimpema, Evgenii O. Tretiakov, Gert Lubec, Joanne Bakker, Miklós Palkovits, Péter Zahola
Publikováno v:
The EMBO Journal
Stress-induced cortical alertness is maintained by a heightened excitability of noradrenergic neurons innervating, notably, the prefrontal cortex. However, neither the signaling axis linking hypothalamic activation to delayed and lasting noradrenergi
Autor:
Gert Lubec, Tibor Harkany, Edit Szodorai, Robert Schnell, Tomas Hökfelt, Katarzyna Malenczyk, Gábor Szabó
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 14, Iss, Pp 108-120 (2018)
Molecular Metabolism, Vol 14, Iss, Pp 108-120 (2018)
Objective Specification of endocrine cell lineages in the developing pancreas relies on extrinsic signals from non-pancreatic tissues, which initiate a cell-autonomous sequence of transcription factor activation and repression switches. The steps in
Autor:
Jan Mulder, Erzsébet Borók, Ludwig Wagner, Tibor Harkany, Roman A. Romanov, Edit Szodorai, Åsa Segerstolpe, Giuseppe Tortoriello, Gert Lubec, Robert Schnell, Stefan Kubicek, Petter Storm, Katarzyna Malenczyk, Gábor Szabó, Tomas Hökfelt, Leif Groop, Fatima Girach, Vincenzo Di Marzo, Fabiana Piscitelli, Rickard Sandberg
Publikováno v:
EMBO journal
36 (2017): 2107–2125. doi:10.15252/embj.201695347
info:cnr-pdr/source/autori:Malenczyk K.; Girach F.; Szodorai E.; Storm P.; Segerstolpe A.; Tortoriello G.; Schnell R.; Mulder J.; Romanov R.A.; Borok E.; Piscitelli F.; Di Marzo V.; Szabo G.; Sandberg R.; Kubicek S.; Lubec G.; Hokfelt T.; Wagner L.; Groop L.; Harkany T./titolo:A TRPV1-to-secretagogin regulatory axis controls pancreatic ?-cell survival by modulating protein turnover/doi:10.15252%2Fembj.201695347/rivista:EMBO journal (Print)/anno:2017/pagina_da:2107/pagina_a:2125/intervallo_pagine:2107–2125/volume:36
The EMBO Journal
36 (2017): 2107–2125. doi:10.15252/embj.201695347
info:cnr-pdr/source/autori:Malenczyk K.; Girach F.; Szodorai E.; Storm P.; Segerstolpe A.; Tortoriello G.; Schnell R.; Mulder J.; Romanov R.A.; Borok E.; Piscitelli F.; Di Marzo V.; Szabo G.; Sandberg R.; Kubicek S.; Lubec G.; Hokfelt T.; Wagner L.; Groop L.; Harkany T./titolo:A TRPV1-to-secretagogin regulatory axis controls pancreatic ?-cell survival by modulating protein turnover/doi:10.15252%2Fembj.201695347/rivista:EMBO journal (Print)/anno:2017/pagina_da:2107/pagina_a:2125/intervallo_pagine:2107–2125/volume:36
The EMBO Journal
Ca 2+ ‐sensor proteins are generally implicated in insulin release through SNARE interactions. Here, secretagogin, whose expression in human pancreatic islets correlates with their insulin content and the incidence of type 2 diabetes, is shown to o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b42c85dc8c370eae6dfc4d435d108e7
https://publications.cnr.it/doc/380829
https://publications.cnr.it/doc/380829
Autor:
Zsófia Hevesi, Giuseppe Tortoriello, Gert Lubec, János Hanics, Zita Puskár, Ludwig Wagner, Mirjam I. Lutz, Katarzyna Malenczyk, Gabor G. Kovacs, Tibor Harkany, Márk Kozsurek, Alán Alpár, Erik Keimpema, Zsuzsanna Tóth, Tomas Hökfelt, Edit Szodorai
Publikováno v:
Proceedings of the National Academy of Sciences
The rostral migratory stream (RMS) is viewed as a glia-enriched conduit of forward-migrating neuroblasts in which chemorepulsive signals control the pace of forward migration. Here we demonstrate the existence of a scaffold of neurons that receive sy
Autor:
Vincenzo Di Marzo, Justyna Janikiewicz, Katarzyna Malenczyk, Ken Mackie, Cristoforo Silvestri, Agnieszka Dobrzyn, Tibor Harkany, Maria Jolanta Redowicz, Magdalena Jazurek, Erik Keimpema
Publikováno v:
Journal of Biological Chemistry; Vol 288
Endocannabinoid signaling has been implicated in modulating insulin release from β cells of the endocrine pancreas. β Cells express CB1 cannabinoid receptors (CB1Rs), and the enzymatic machinery regulating anandamide and 2-arachidonoylglycerol bioa
Autor:
Daniela Calvigioni, Ken Mackie, Katarzyna Malenczyk, Tomas Hökfelt, Peyman Björklund, Erik Keimpema, Agnieszka Dobrzyn, Vincenzo Di Marzo, Fabiana Piscitelli, Tibor Harkany
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America 112 (2015): E6185–E6194. doi:10.1073/pnas.1519040112
info:cnr-pdr/source/autori:Malenczyk K.; Keimpema E.; Piscitelli F.; Calvigioni D.; Bjorklund P.; Mackie K.; Marzo V.D.; Hokfelt T.G.M.; Dobrzyn A.; Harkany T./titolo:Fetal endocannabinoids orchestrate the organization of pancreatic islet microarchitecture/doi:10.1073%2Fpnas.1519040112/rivista:Proceedings of the National Academy of Sciences of the United States of America/anno:2015/pagina_da:E6185/pagina_a:E6194/intervallo_pagine:E6185–E6194/volume:112
info:cnr-pdr/source/autori:Malenczyk K.; Keimpema E.; Piscitelli F.; Calvigioni D.; Bjorklund P.; Mackie K.; Marzo V.D.; Hokfelt T.G.M.; Dobrzyn A.; Harkany T./titolo:Fetal endocannabinoids orchestrate the organization of pancreatic islet microarchitecture/doi:10.1073%2Fpnas.1519040112/rivista:Proceedings of the National Academy of Sciences of the United States of America/anno:2015/pagina_da:E6185/pagina_a:E6194/intervallo_pagine:E6185–E6194/volume:112
Endocannabinoids are implicated in the control of glucose utilization and energy homeostasis by orchestrating pancreatic hormone release. Moreover, in some cell niches, endocannabinoids regulate cell proliferation, fate determination, and migration.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07acb9a5f04fabd296b84299fa8e75a4
http://www.cnr.it/prodotto/i/342410
http://www.cnr.it/prodotto/i/342410
Autor:
Carl Hobbs, Tibor Harkany, Kenji Sakimura, Yasmin L. Hurd, Masahiko Watanabe, Katarzyna Malenczyk, Masanobu Kano, Erik Keimpema, Fiona V. Howell, Alán Alpár, Patrick Doherty
Publikováno v:
Scientific Reports
Endocannabinoids are small signaling lipids, with 2-arachidonoylglycerol (2-AG) implicated in modulating axonal growth and synaptic plasticity. The concept of short-range extracellular signaling by endocannabinoids is supported by the lack of trans-s