Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Katarzyna M. Piekarz"'
Autor:
Shylesh Bhaskaran, Gaurav Kumar, Nidheesh Thadathil, Katarzyna M. Piekarz, Sabira Mohammed, Sergio Dominguez Lopez, Rizwan Qaisar, Dorothy Walton, Jacob L. Brown, Ashley Murphy, Nataliya Smith, Debra Saunders, Michael J. Beckstead, Scott Plafker, Tommy L. Lewis, Jr., Rheal Towner, Sathyaseelan S. Deepa, Arlan Richardson, Robert C. Axtell, Holly Van Remmen
Publikováno v:
Redox Biology, Vol 59, Iss , Pp 102550- (2023)
Neuronal oxidative stress has been implicated in aging and neurodegenerative disease. Here we investigated the impact of elevated oxidative stress induced in mouse spinal cord by deletion of Mn-Superoxide dismutase (MnSOD) using a neuron specific Cre
Externí odkaz:
https://doaj.org/article/81eb975c107342e8860817ab0704bc01
Autor:
Hongyang Xu, Shylesh Bhaskaran, Katarzyna M. Piekarz, Rojina Ranjit, Jan Bian, Parker Kneis, Aubrey Ellis, Suyesha Bhandari, Heather C. Rice, Holly Van Remmen
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Emerging evidence suggests that patients with Alzheimer’s disease (AD) may show accelerated sarcopenia phenotypes. To investigate whether pathological changes associated with neuronal death and cognitive dysfunction also occur in peripheral motor n
Externí odkaz:
https://doaj.org/article/33029d926d524910bcfb714ac428edef
Autor:
Bumsoo Ahn, Rojina Ranjit, Pavithra Premkumar, Gavin Pharaoh, Katarzyna M. Piekarz, Satoshi Matsuzaki, Dennis R. Claflin, Kaitlyn Riddle, Jennifer Judge, Shylesh Bhaskaran, Kavithalakshmi Satara Natarajan, Erika Barboza, Benjamin Wronowski, Michael Kinter, Kenneth M. Humphries, Timothy M. Griffin, Willard M. Freeman, Arlan Richardson, Susan V. Brooks, Holly Van Remmen
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 10, Iss 2, Pp 411-428 (2019)
Abstract Background Excess reactive oxygen species (ROS) and muscle weakness occur in parallel in multiple pathological conditions. However, the causative role of skeletal muscle mitochondrial ROS (mtROS) on neuromuscular junction (NMJ) morphology an
Externí odkaz:
https://doaj.org/article/bf068644f5f343948ea2be767d068283
Autor:
Christopher J Johnson, Florian Razy-Krajka, Fan Zeng, Katarzyna M Piekarz, Shweta Biliya, Ute Rothbächer, Alberto Stolfi
Publikováno v:
PLoS Biology, Vol 22, Iss 3, p e3002555 (2024)
The papillae of tunicate larvae contribute sensory, adhesive, and metamorphosis-regulating functions that are crucial for the biphasic lifestyle of these marine, non-vertebrate chordates. We have identified additional molecular markers for at least 5
Externí odkaz:
https://doaj.org/article/83992b07e2734c8d81e01ee0b87aaa23
Autor:
Christopher J. Johnson, Florian Razy-Krajka, Fan Zeng, Katarzyna M. Piekarz, Shweta Biliya, Ute Rothbächer, Alberto Stolfi
The papillae of tunicate larvae contribute sensory, adhesive, and metamorphosis-regulating functions that are crucial for the biphasic lifestyle of these marine, non-vertebrate chordates. We have identified additional molecular markers for at least f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d08765e7b123d4f8d6c5a07cf305d0ac
https://doi.org/10.1101/2023.05.02.539060
https://doi.org/10.1101/2023.05.02.539060
Autor:
Katarzyna M, Piekarz, Constantin, Georgescu, Jonathan D, Wren, Rheal A, Towner, Holly, Van Remmen
Publikováno v:
GeroScience
Aging is associated with molecular and functional declines in multiple physiologic systems. We have previously reported age-related changes in spinal cord that included a decline in α-motor neuron numbers, axonal loss, and demyelination associated w
Autor:
Shylesh Bhaskaran, Gaurav Kumar, Nidheesh Thadathil, Katarzyna M. Piekarz, Sabira Mohammed, Sergio Dominguez Lopez, Rizwan Qaisar, Dorothy Walton, Jacob L. Brown, Ashley Murphy, Nataliya Smith, Debra Saunders, Michael J. Beckstead, Scott Plafker, Tommy L. Lewis, Rheal Towner, Sathyaseelan S. Deepa, Arlan Richardson, Robert C. Axtell, Holly Van Remmen
Publikováno v:
Redox biology. 59
Neuronal oxidative stress has been implicated in aging and neurodegenerative disease. Here we investigated the impact of elevated oxidative stress induced in mouse spinal cord by deletion of Mn-Superoxide dismutase (MnSOD) using a neuron specific Cre
Autor:
Bumsoo Ahn, Parker Kneis, Arlan Richardson, Michael Kinter, Chase A. Brown, Benjamin F. Miller, Jacob L. Brown, Katarzyna M. Piekarz, Gavin Pharaoh, Rizwan Qaisar, Rojina Ranjit, Jan Bian, Holly Van Remmen, Fredrick F. Peelor, Marcus M. Lawrence
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle
Background Cancer is associated with muscle atrophy (cancer cachexia) that is linked to up to 40% of cancer‐related deaths. Oxidative stress is a critical player in the induction and progression of age‐related loss of muscle mass and weakness (sa
Autor:
Willard M. Freeman, Kaitlyn Street, Michael Kinter, Caroline S. Kinter, Jonathan D. Wren, Rojina Ranjit, Katarzyna M. Piekarz, Arlan Richardson, Holly Van Remmen, Constantin Georgescu, Jacob L. Brown, Gavin Pharaoh, Kavithalakshmi Sataranatarajan
Publikováno v:
GeroScience
Mice lacking the superoxide anion scavenger CuZn superoxide dismutase (Sod1(−/−) mice) develop a number of age-related phenotypes, including an early progression of muscle atrophy and weakness (sarcopenia) associated with loss of innervation. The
Autor:
Holly Van Remmen, Michelle Zalles, Debra Saunders, Jaime L. Laurin, Rheal A. Towner, Shadi Khademi, Shylesh Bhaskaran, Pavithra Premkumar, Rick Peelor, Katarzyna M. Piekarz, Benjamin F. Miller, Kavithalakshmi Sataranatarajan, Rafal Gulej, Kaitlyn Street
Publikováno v:
GeroScience
Age-related muscle weakness and loss of muscle mass (sarcopenia) is a universal problem in the elderly. Our previous studies indicate that alpha motor neurons (α-MNs) play a critical role in this process. The goal of the current study is to uncover