Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Katarzyna M. Kedziora"'
Autor:
Sayan Ghosh, Ruchi Sharma, Sridhar Bammidi, Victoria Koontz, Mihir Nemani, Meysam Yazdankhah, Katarzyna M. Kedziora, Donna Beer Stolz, Callen T. Wallace, Cheng Yu-Wei, Jonathan Franks, Devika Bose, Peng Shang, Helena M. Ambrosino, James R. Dutton, Zhaohui Geng, Jair Montford, Jiwon Ryu, Dhivyaa Rajasundaram, Stacey Hose, José-Alain Sahel, Rosa Puertollano, Toren Finkel, J. Samuel Zigler, Yuri Sergeev, Simon C. Watkins, Eric S. Goetzman, Deborah A. Ferrington, Miguel Flores-Bellver, Kai Kaarniranta, Akrit Sodhi, Kapil Bharti, James T. Handa, Debasish Sinha
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Non-neovascular or dry age-related macular degeneration (AMD) is a multi-factorial disease with degeneration of the aging retinal-pigmented epithelium (RPE). Lysosomes play a crucial role in RPE health via phagocytosis and autophagy, which a
Externí odkaz:
https://doaj.org/article/9a768d2563fb4e4f839cd5a860fabad3
Autor:
Michael J. Cotton, Pablo Ariel, Kaiwen Chen, Vanessa A. Walcott, Michelle Dixit, Keith A. Breau, Caroline M. Hinesley, Katarzyna M. Kedziora, Cynthia Y. Tang, Anna Zheng, Scott T. Magness, Joseph Burclaff
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract The intestinal epithelium dynamically controls cell cycle, yet no experimental platform exists for directly analyzing cell cycle phases in non-immortalized human intestinal epithelial cells (IECs). Here, we present two reporters and a comple
Externí odkaz:
https://doaj.org/article/2166ab0898f7409294e33d7ee9771520
Autor:
Phillip G. Durham, Ashelyn E. Sidders, Jenna E. Beam, Katarzyna M. Kedziora, Paul A. Dayton, Brian P. Conlon, Virginie Papadopoulou, Sarah E. Rowe
Publikováno v:
Biofilm, Vol 3, Iss , Pp 100049- (2021)
Bacterial biofilms, often associated with chronic infections, respond poorly to antibiotic therapy and frequently require surgical intervention. Biofilms harbor persister cells, metabolically indolent cells, which are tolerant to most conventional an
Externí odkaz:
https://doaj.org/article/ed9cc9a73dc4482bb59e56b77037462b
Autor:
Kathryn M. Headley, Katarzyna M. Kedziora, Aidin Alejo, Elianna Zhi-Xiang Lai, Jeremy E. Purvis, Nathaniel A. Hathaway
Publikováno v:
Stem Cell Research, Vol 38, Iss , Pp - (2019)
Here we utilized the chromatin in vivo assay (CiA) mouse platform to directly examine the epigenetic barriers impeding the activation of the CiA:Oct4 allele in mouse embryonic fibroblasts (MEF)s when stimulated with a transcription factor. The CiA:Oc
Externí odkaz:
https://doaj.org/article/32351aaaf3894319a827aa5bbfe3b5ad
Autor:
Daniela Leyton-Puig, Katarzyna M. Kedziora, Tadamoto Isogai, Bram van den Broek, Kees Jalink, Metello Innocenti
Publikováno v:
Biology Open, Vol 5, Iss 7, Pp 1001-1009 (2016)
Super-resolution microscopy (SRM) allows precise localization of proteins in cellular organelles and structures, including the actin cytoskeleton. Yet sample preparation protocols for SRM are rather anecdotal and still being optimized. Thus, SRM-base
Externí odkaz:
https://doaj.org/article/8f3bdf4392c8494fb004c17914ee4257
AGS3 antagonizes LGN to balance oriented cell divisions and cell fate choices in mammalian epidermis
Autor:
Carlos Patiño Descovich, Kendall J. Lough, Akankshya Jena, Jessica J Wu, Jina Yom, Danielle C. Spitzer, Manuela Uppalapati, Katarzyna M. Kedziora, Scott E. Williams
Publikováno v:
eLife. 12
Oriented cell divisions balance self-renewal and differentiation in stratified epithelia such as the skin epidermis. During peak epidermal stratification, the distribution of division angles among basal keratinocyte progenitors is bimodal, with plana
Autor:
Gabrielle R Budziszewski, Yani Zhao, Cathy J Spangler, Katarzyna M Kedziora, Michael R Williams, Dalal N Azzam, Aleksandra Skrajna, Yuka Koyama, Andrew P Cesmat, Holly C Simmons, Eyla C Arteaga, Joshua D Strauss, Dmitri Kireev, Robert K McGinty
Publikováno v:
Nucleic Acids Research. 50:4355-4371
A key role of chromatin kinases is to phosphorylate histone tails during mitosis to spatiotemporally regulate cell division. Vaccinia-related kinase 1 (VRK1) is a serine–threonine kinase that phosphorylates histone H3 threonine 3 (H3T3) along with
Autor:
Carlos P Descovich, Kendall J Lough, Akankshya Jena, Jessica J Wu, Jina Yom, Danielle C Spitzer, Manuela Uppalapati, Katarzyna M Kedziora, Scott E Williams
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e691c847c33d38e4a3665a72061041a
https://doi.org/10.7554/elife.80403.sa2
https://doi.org/10.7554/elife.80403.sa2
Autor:
Ashelyn E Sidders, Katarzyna M Kedziora, Melina Arts, Jan-Martin Daniel, Stefania de Benedetti, Jenna E Beam, Duyen T Bui, Joshua B Parsons, Tanja Schneider, Sarah E Rowe, Brian P Conlon
Publikováno v:
eLife. 12
Antibiotic tolerance and antibiotic resistance are the two major obstacles to the efficient and reliable treatment of bacterial infections. Identifying antibiotic adjuvants that sensitize resistant and tolerant bacteria to antibiotic killing may lead
Publikováno v:
Nucleic Acids Research. 50:9601-9620
Eukaryotic chromosomes contain regions of varying accessibility, yet DNA replication factors must access all regions. The first replication step is loading MCM complexes to license replication origins during the G1 cell cycle phase. It is not yet kno