Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Katarzyna Lubelska"'
Autor:
Lidia Śliwka, Katarzyna Wiktorska, Piotr Suchocki, Małgorzata Milczarek, Szymon Mielczarek, Katarzyna Lubelska, Tomasz Cierpiał, Piotr Łyżwa, Piotr Kiełbasiński, Anna Jaromin, Anna Flis, Zdzisław Chilmonczyk
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0155772 (2016)
Multiple in vitro tests are widely applied to assess the anticancer activity of new compounds, including their combinations and interactions with other drugs. The MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide) assay is one of the
Externí odkaz:
https://doaj.org/article/a772b63798ca4280bfa8fef6ecd6e43c
Autor:
Małgorzata Milczarek, Lidia Mielczarek, Katarzyna Lubelska, Aleksandra Dąbrowska, Zdzisław Chilmonczyk, Dariusz Matosiuk, Katarzyna Wiktorska
Publikováno v:
Molecules, Vol 23, Iss 11, p 3040 (2018)
Isothiocyanates (R-NCS) are sulphur-containing phytochemicals. The main source are plants of the Brassicaceae family. The best known plant-derived isothiocyanate is sulforaphane that has exhibited anticancer activity in both in vivo and in vitro stud
Externí odkaz:
https://doaj.org/article/24bea7ab970d4efb92719fd5ec32ef1b
Autor:
Anna Szurpnicka, Anna Katarzyna Wrońska, Katarzyna Bus, Aleksandra Kozińska, Renata Jabłczyńska, Arkadiusz Szterk, Katarzyna Lubelska
Publikováno v:
Journal of Ethnopharmacology. 298:115604
Viscum album L. (European mistletoe), a member of the Santalaceae, is a hemiparasitic, evergreen shrub growing on deciduous and coniferous trees. In traditional and folk medicine, mistletoe was used for the treatment of central nervous system disorde
Autor:
Lech Kozerski, Jerzy Sitkowski, Wojciech Bocian, Katarzyna Wiktorska, Marcin Górecki, Katarzyna Lubelska, Elżbieta Bednarek, Beata Naumczuk, Małgorzata Milczarek, Magdalena Urbanowicz
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 46:128146
Derivatives of SN38 were synthesized that were either monosubstituted at C-5 or C-9 or disubstituted at both C-5 and C-9. Substitution to C-5 led to the generation of pairs of diastereomers (2c-2 h) in a one-pot reaction and was readily separable by
Autor:
Janina Drozd, Irena Bubko, Zdzisław Chilmonczyk, Elżbieta Anuszewska, Jadwiga Marczewska, Katarzyna Lubelska, Ewa Drozd, Magda Bielak, Jolanta Krzysztoń-Russjan, Katarzyna Wiktorska, Beata M. Gruber-Bzura
Publikováno v:
Biomedicine & Pharmacotherapy. 83:397-406
Doxorubicin (DOX), one of the most effective anticancer drugs, acts in a variety of ways including DNA damage, enzyme inhibition and generation of reactive oxygen species. Glutathione (GSH) and glutathione-related enzymes including: glutathione perox
Autor:
Ilona Zbroińska-Bregisz, Katarzyna Wiktorska, Lidia Mielczarek, Katarzyna Lubelska, Małgorzata Milczarek, Zdzisław Chilmonczyk
Publikováno v:
Nutrition and Cancer. 68:1338-1348
Sulforaphane (SFN), a naturally occurring chemopreventive and anticancer agent, is a nuclear factor, erythroid 2-like 2 (NFE2L2/Nrf2) inducer. Nrf2 plays a critical role in coordinating the cell defense system by initiating the transcription of cytop
Autor:
Anna Flis-Borsuk, Lidia Śliwka, Zofia Suchocka, Jakub Borsuk, Zbigniew Fijałek, Katarzyna Lubelska, Piotr Suchocki
Publikováno v:
Prospects in Pharmaceutical Sciences. 14:17-24
Selol jest mieszaniną seleninotriglicerydów, stanowiących unikalne związki zawierające selen na +4 stopniu utlenienia. Wyniki dotychczasowych badań in vitro i in vivo przedstawiają przemiany i zależności, kluczowe dla poznania mechanizmu dzi
Autor:
Katarzyna Wiktorska, Jerzy Sitkowski, Robert Kawęcki, Katarzyna Lubelska, Lech Kozerski, Elżbieta Bednarek, Zdzisław Chilmonczyk, Wojciech Bocian, Beata Naumczuk
Publikováno v:
New Journal of Chemistry. 40:7978-7985
9-Aminomethyl derivatives of 7-ethyl-10-hydroxycamptothecin were synthesized. Interaction with a natural DNA octamer was checked using 1H NMR, PFGSE NMR and MALDI-TOF experiments, which proved covalent binding. Compounds were tested against human can
Autor:
Katarzyna Lubelska, Tomasz Cierpiał, Piotr Łyżwa, Katarzyna Wiktorska, Aleksandra Dąbrowska, Piotr Kiełbasiński, Lidia Mielczarek, Zdzisław Chilmonczyk, Hanna Kruszewska, Małgorzata Kwiatkowska, Dominika Kuran
Publikováno v:
Bioorganic Chemistry. 94:103454
A series of new sulforaphane analogs bearing various (poly)fluoroaryl substituents bonded to the sulfinyl sulfur atom in place of the original methyl group and having different number of methylene groups in the central alkyl chain were synthesized an
Autor:
Dariusz Matosiuk, Katarzyna Wiktorska, Katarzyna Lubelska, Zdzisław Chilmonczyk, Aleksandra Dąbrowska, Lidia Mielczarek, Małgorzata Milczarek
Publikováno v:
Molecules
Volume 23
Issue 11
Molecules, Vol 23, Iss 11, p 3040 (2018)
Volume 23
Issue 11
Molecules, Vol 23, Iss 11, p 3040 (2018)
Isothiocyanates (R-NCS) are sulphur-containing phytochemicals. The main source are plants of the Brassicaceae family. The best known plant-derived isothiocyanate is sulforaphane that has exhibited anticancer activity in both in vivo and in vitro stud