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pro vyhledávání: '"Katarzyna Krzykowska-Petitjean"'
Autor:
Anna Bentke, Piotr Laidler, Katarzyna Krzykowska-Petitjean, Barbara Ostrowska, Jędrzej Małecki
Publikováno v:
Cancer Investigation. 31:545-549
Many anticancer strategies rely on efficient induction of apoptosis. The need for development of drug combinations with a strong pro-apoptotic activity is of particular interest in melanoma resistant to currently available chemotherapeutic regimes. W
Autor:
Jędrzej Małecki, Barbara Ostrowska, Piotr Laidler, Anna Bentke, Katarzyna Krzykowska-Petitjean
Publikováno v:
Journal of Cancer Research and Clinical Oncology
Background Farnesyltransferase inhibitor tipifarnib (R115777) has been used for treatment of hematological malignancies; however, its observed anticancer effect was limited. This prompted us to search for inhibitors that would show synergic, proapopt