Výsledky vyhledávání - "Katarzyna Kopańska"

Synthesis of new analogs of benzotriazole, benzimidazole and phthalimide—potential inhibitors of human protein kinase CK2

Autor: Maja Łebska, Grażyna Muszyńska, Katarzyna Kopańska, Andrzej Orzeszko, Maria Bretner, Andzelika Najda-Bernatowicz, Ewa Krzywińska

Publikováno v: Bioorganic & Medicinal Chemistry. 17:1573-1578

New derivatives of 4,5,6,7-tetrabromo-1H-1,2,3-benzotriazole (TBBt), 4,5,6,7-tetrabromo-1H-benzimidazole (TBBi), and N-substituted tetrabromophthalimides were synthesized and their effect on the activity of human protein kinase CK2 was examined. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9f23aff9309e7c3c5f6bede56d12298
https://doi.org/10.1016/j.bmc.2008.12.071

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Searching for a new anti-HCV therapy: Synthesis and properties of tropolone derivatives

Autor: Andżelika Najda, Katarzyna Kopańska, Maria Bretner, Anna M. Boguszewska-Chachulska, Mariusz Krawczyk, Wlodzimierz Zagorski-Ostoja, Anna Stankiewicz-Drogoń

Publikováno v: Biochemical and Biophysical Research Communications. 341:641-647

Hepatitis C virus (HCV) is considered one of the most dangerous pathogens since about 3% of the world population is HCV-infected and the virus is a major cause of hepatitis, cirrhosis, and liver carcinoma. A need for a more efficient therapy prompted

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0a51dcba1d5992b81c8e2feb5dc0a8f
https://doi.org/10.1016/j.bbrc.2006.01.015

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Synthesis and Biological Activity of 1H-benzotriazole and 1H-benzimidazole Analogues — Inhibitors of the NTPase/Helicase of HCV and of Some Related Flaviviridae

Autor: Peter Borowski, Maria Bretner, Anna Schoof, Tadeusz Kulikowski, Andrzej Piasek, Andrea Baier, Katarzyna Kopańska, Andżelika Najda, Michael Reinholz, Andrzej Lipniacki

Publikováno v: Antiviral Chemistry and Chemotherapy. 16:315-326

To improve anti-helical activity of analogues of 1 H-benzotriazole and 1 H-benzimidazole their N-alkyl derivatives were synthesized and tested for anti-helicase activity against enzymes of selected Flaviviridae including hepatitis C virus (HCV), West

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1465b0b8df85f2b447f0faab66f727f8
https://doi.org/10.1177/095632020501600504

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Synthesis and activity of 1H-benzimidazole and 1H-benzotriazole derivatives as inhibitors of Acanthamoeba castellanii

Autor: Katarzyna Kopańska, Justyna Żebrowska, Andżelika Najda, Lidia Chomicz, Przemysław Myjak, Maria Bretner, J Piekarczyk

Publikováno v: Bioorganic & Medicinal Chemistry. 12:2617-2624

Chloro-, bromo- and methyl- analogues of 1H-benzimidazole and 1H-benzotriazole and their N-alkyl derivatives have been synthesized and tested in vitro against the protozoa Acanthamoeba castellanii. The results indicate that 5,6-dimethyl-1H-benzotriaz

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4b98a57426a3b4b7668001ba85de925
https://doi.org/10.1016/j.bmc.2004.03.022

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Corrigendum to 'Synthesis and activity of 1H-benzimidazole and 1H-benzotriazole derivatives as inhibitors of Acanthamoeba castellanii' [Bioorg. Med. Chem. 12 (2004) 2617]

Autor: Justyna Żebrowska, Maria Bretner, Przemysław Myjak, Lidia Chomicz, Andżelika Najda, Katarzyna Kopańska, J Piekarczyk

Publikováno v: Bioorganic & Medicinal Chemistry. 13:3601

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::695f8f12cdd7db0fbaf36836de0713f1
https://doi.org/10.1016/j.bmc.2005.02.048

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