Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Katarzyna Klich"'
Autor:
Paulina Pecyna, Marzena Gajecka, Marietta Blecha, Piotr Przybylski, Anna Janas, Krystian Pyta, Katarzyna Klich
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 26:4322-4326
Synthetic limitations in the copper-catalyzed azide alkyne cycloaddition (CuAAC) on gossypol's skeleton functionalized with alkyne (2) or azide (3) groups have been indicated. Modified approach to the synthesis of new gossypol-triazole conjugates yie
Autor:
Krystian Pyta, Marzena Gajecka, Piotr Przybylski, Lech Celewicz, Piotr Ruszkowski, Katarzyna Klich, Marcelina M. Kubicka
Publikováno v:
Journal of Medicinal Chemistry. 59:7963-7973
Huisgen cycloaddition allowed obtaining of novel triazole-bridged antibiotics (6-16) with the reconstructed C(5) arm of spiramycin. (1)H-(1)H NOESY couplings indicated the structure of novel derivatives in solution and demonstrated that the rebuilt C
Autor:
Bohdan Kamieński, A. Szady-Chełmieniecka, Katarzyna Klich, B. Kołodziej, Eugeniusz Grech, Bogumil Brzezinski, Krystian Pyta, Wojciech Schilf, Piotr Przybylski
Publikováno v:
Structural Chemistry. 25:1733-1746
Structures of the main resonance and tautomeric forms of three Schiff bases of 2-hydroxy-1-naphthaldehyde (1OXA), 5-bromosalicylaldehyde (2OXA) and 5-nitrosalicylaldehyde (3OXA) with 1,8-diamine-3,6-dioxaoctane, before and after protonation and compl
Publikováno v:
Magnetic Resonance in Chemistry. 52:10-21
13C, 15N CP/MAS, including 1H–13C and 1H–15N short contact time CP/MAS experiments, and FTIR methods were applied for detailed structural characterization of ansa-macrolides as 3-formylrifamycin SV (1) and its derivatives (2–6) in crystal and i
Publikováno v:
The Journal of organic chemistry. 80(14)
Functionalization of 16-membered aglycone of spiramycin with the use of intramolecular cascade strategy yielded access to novel types of diastereopure bicyclic spiramycin derivatives containing tetrahydrofuran ring. Experimental results shows that a
Publikováno v:
European journal of medicinal chemistry. 84
Thirty four novel derivatives of 3-formylrifamycin SV were synthesized via reductive alkylation and copper(I)-catalysed azide-alkyne cycloaddition. According to the obtained results, 'click chemistry' can be successfully applied for modification of s
Publikováno v:
Magnetic resonance in chemistry : MRC. 52(1-2)
(13)C, (15)N CP/MAS, including (1)H-(13)C and (1)H-(15)N short contact time CP/MAS experiments, and FTIR methods were applied for detailed structural characterization of ansa-macrolides as 3-formylrifamycin SV (1) and its derivatives (2-6) in crystal
Publikováno v:
Organic & Biomolecular Chemistry. 10:8283
Seven new benzyl (3-9) and four new phenethyl (10-13) amino analogues of ansa-macrolide rifampicin (1) were synthesized using the optimised method of reductive amination. Structures of 3-13 in solution were determined by 1D and 2D NMR and FT-IR metho