Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Katarzyna E. Schewe"'
Autor:
Katarzyna E. Schewe, Shaun Cooper, Jonathan Crowe, Steffan Llewellyn, Lydia Ritter, Kathryn A. Ryan, Oliver Dibben
Publikováno v:
Vaccines, Vol 12, Iss 11, p 1275 (2024)
Between 2013 and 2016, the A/H1N1pdm09 component of the live attenuated influenza vaccine (LAIV) produced instances of lower-than-expected vaccine effectiveness. Standard pre-clinical ferret models, using a human-like vaccine dose and focusing on ant
Externí odkaz:
https://doaj.org/article/1b44cb6ef2714feeb86179b83a8f78ec
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-12 (2021)
Abstract In the 2013–14 and 2015–16 influenza seasons, reduced vaccine effectiveness (VE) was observed for the H1N1 component of the FluMist quadrivalent live attenuated influenza vaccine (QLAIV) in the USA, leading to loss of Advisory Committee
Externí odkaz:
https://doaj.org/article/f71a211b8c824cb3b3b14d74a8b7cf35
Autor:
Rachael Dempsey, Giulia Tamburrino, Katarzyna E Schewe, Jonathan Crowe, Annalisa Nuccitelli, Oliver Dibben
Publikováno v:
PLoS Pathogens, Vol 18, Iss 5, p e1010585 (2022)
During 2013-14 and 2015-16, A/H1N1pdm09 live attenuated influenza vaccine (LAIV) viruses replicated inefficiently in primary human nasal epithelial cells (hNEC). This led to reduced vaccine effectiveness (VE) in quadrivalent formulations, mediated by
Externí odkaz:
https://doaj.org/article/3b5e407ef67d48899c169b7697390879
Autor:
Kathryn A Ryan, Katarzyna E Schewe, Jonathan Crowe, Susan A Fotheringham, Yper Hall, Richard Humphreys, Anthony C Marriott, Jemma Paterson, Emma Rayner, Francisco J Salguero, Robert J Watson, Catherine J Whittaker, Miles W Carroll, Oliver Dibben
Publikováno v:
The Journal of Infectious Diseases. 225:404-412
Cocirculation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and influenza viruses could pose unpredictable risks to health systems globally, with recent studies suggesting more severe disease outcomes in coinfected patients. The ini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce29ba68b8706c4b49fad8ae732d41b5
https://doi.org/10.1093/infdis/jiab594
https://doi.org/10.1093/infdis/jiab594
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-12 (2021)
NPJ Vaccines
NPJ Vaccines
In the 2013–14 and 2015–16 influenza seasons, reduced vaccine effectiveness (VE) was observed for the H1N1 component of the FluMist quadrivalent live attenuated influenza vaccine (QLAIV) in the USA, leading to loss of Advisory Committee on Immuni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7388019d35c49da20d8a83304de1796e
https://doaj.org/article/f71a211b8c824cb3b3b14d74a8b7cf35
https://doaj.org/article/f71a211b8c824cb3b3b14d74a8b7cf35
Autor:
Kathryn A. Ryan, Jonathan Crowe, Katarzyna E Schewe, Robert J. Watson, Richard Humphreys, Catherine J. Whittaker, Jemma Paterson, Miles W. Carroll, Francisco J. Salguero, Yper Hall, Oliver Dibben, Emma Rayner, Anthony C. Marriott, Susan A. Fotheringham
Co-circulation of SARS-CoV-2 and influenza viruses could pose unpredictable risks to health systems globally, with recent studies suggesting more severe disease outcomes in co-infected patients. The lack of a readily available COVID-19 vaccine has re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95f5a8522d5d2a219d4fecf29f94301a
https://doi.org/10.1101/2021.02.01.429110
https://doi.org/10.1101/2021.02.01.429110
Publikováno v:
Journal of medicinal chemistry. 51(24)
Pyridine substituted naphthalenes (e.g., I-III) constitute a class of potent inhibitors of aldosterone synthase (CYP11B2). To overcome the unwanted inhibition of the hepatic enzyme CYP1A2, we aimed at reducing the number of aromatic carbons of these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65f8852c2b9a41edfac80286e3901f98
https://pubmed.ncbi.nlm.nih.gov/19049427
https://pubmed.ncbi.nlm.nih.gov/19049427
Autor:
Katarzyna E. Schewe, Ursula Müller-Vieira, Christina Ries, Matthias Negri, Rolf W. Hartmann, Cornelia M. Grombein, Simon Lucas, Barbara Birk, Ralf Heim
Publikováno v:
Journal of medicinal chemistry. 51(16)
Recently, we reported on the development of potent and selective inhibitors of aldosterone synthase (CYP11B2) for the treatment of congestive heart failure and myocardial fibrosis. A major drawback of these nonsteroidal compounds was a strong inhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59f3a4a782188b45cb68a3b92f880952
https://pubmed.ncbi.nlm.nih.gov/18672861
https://pubmed.ncbi.nlm.nih.gov/18672861
Autor:
Gianluca Sbardella, Rolf W. Hartmann, Antonia Caroli, Marisabella Santoriello, Katarzyna E. Schewe, Sabrina Castellano, Rino Ragno, Giorgio Stefancich
Several derivatives out of a series of antifungal agents exhibited a good inhibitory potency against aromatase as well as a fairly good selectivity toward CYP17, even if lacking H-bond accepting substituents. Their common structural feature is a flex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de7acceb5316889774d3c57172925d0a
http://hdl.handle.net/11573/120901
http://hdl.handle.net/11573/120901
Publikováno v:
Journal of Medicinal Chemistry; Dec2008, Vol. 51 Issue 24, p8077-8087, 11p