Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Katarzyna D. Bieganowska"'
Autor:
Katarzyna D. Bieganowska, Beatriz M. Carreno, David A. Hafler, David E. Anderson, Mary Collins, Amit Bar-Or, Enedina Maria Lobato de Oliveira
Publikováno v:
Nature Medicine. 6:211-214
T-cell co-stimulation delivered by the molecules B7-1 or B7-2 through CD28 has a positive effect on T-cell activation, whereas engagement of cytotoxic T-lymphocyte antigen 4 (CTLA-4) by these molecules inhibits activation. In vivo administration to m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::803505eb9c02ac6fb693883f868e4936
https://doi.org/10.1038/72323
https://doi.org/10.1038/72323
Direct Ex Vivo Analysis of Activated, Fas-sensitive Autoreactive T Cells in Human Autoimmune Disease
Autor:
Elissa Slovik, Katarzyna D. Bieganowska, Lara J. Ausubel, David A. Hafler, Yalda Modabber, Wells A. Messersmith
Publikováno v:
The Journal of Experimental Medicine
The frequency of clonally expanded and persistent T cells recognizing the immunodominant autoantigenic peptide of myelin basic protein (MBP)p85-99 was directly measured ex vivo in subjects with typical relapsing remitting multiple sclerosis (MS). T c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8ff5a21369901b8cbafa78186b7b4a2
https://doi.org/10.1084/jem.185.9.1585
https://doi.org/10.1084/jem.185.9.1585
Publikováno v:
Cellular immunology. 193(1)
We have determined that certain altered peptide ligands (APLs) can induce T-cells specific for the native peptide myelin basic protein (MBP) p85-99 to secrete Th2-type cytokines such as IL-4 and IL-5 in the absence of significant Th1-type cytokines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bacc6d3c6c66776bf3cfc23c50594be
https://pubmed.ncbi.nlm.nih.gov/10202117
https://pubmed.ncbi.nlm.nih.gov/10202117